Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Julio C Barredo"'
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e74420 (2013)
The outcome of patients with resistant phenotypes of acute lymphoblastic leukemia (ALL) or those who relapse remains poor. We investigated the mechanism of cell death induced by metformin in Bp- and T-ALL cell models and primary cells, and show that
Externí odkaz:
https://doaj.org/article/fb5938589d304fcdb719320ab64fac0f
Autor:
Julio C. Barredo, Theodore J. Lampidis, Guy J. Leclerc, Gilles M. Leclerc, Jianfeng Du, Jeffim N. Kuznetsov, Joanna DeSalvo
The ability to pair the regulation of metabolism and cellular energetics with oncogenes and tumor suppressor genes provides cancer cells with a growth and survival advantage over normal cells. We investigated the mechanism of cell death induced by 2-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b11bc58bb06a7b0721f066cad99407c0
https://doi.org/10.1158/1541-7786.c.6541816
https://doi.org/10.1158/1541-7786.c.6541816
Autor:
Julio C. Barredo, Ramin Shiekhattar, Felipe Beckedorff, Bin Li, Guy J. Leclerc, Anna Shvab, Guangyan Sun
Acute lymphoblastic leukemia (ALL) is a leading cause of cancer-related death in children and adolescents, and cure rates for relapsed/refractory ALL remain dismal, highlighting the need for novel targeted therapies. To identify genome-wide metabolic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38f573030d9f98595553a0c672688131
https://doi.org/10.1158/1541-7786.c.6544916
https://doi.org/10.1158/1541-7786.c.6544916
Autor:
Julio C. Barredo, Theodore J. Lampidis, Guy J. Leclerc, Gilles M. Leclerc, Jianfeng Du, Jeffim N. Kuznetsov, Joanna DeSalvo
PDF file - 114K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ad631281931f07e0561b902b3c819f1
https://doi.org/10.1158/1541-7786.22517752
https://doi.org/10.1158/1541-7786.22517752
Autor:
Julio C. Barredo, Theodore J. Lampidis, Guy J. Leclerc, Gilles M. Leclerc, Jianfeng Du, Jeffim N. Kuznetsov, Joanna DeSalvo
PDF file - 707K, Salubrinal does not protect ALL from apoptosis induced by the inhibitors of N-linked glycosylation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30a86d1592439a9cc3edad0eb49baa9e
https://doi.org/10.1158/1541-7786.22517761
https://doi.org/10.1158/1541-7786.22517761
Autor:
Julio C. Barredo, Theodore J. Lampidis, Guy J. Leclerc, Gilles M. Leclerc, Jianfeng Du, Jeffim N. Kuznetsov, Joanna DeSalvo
PDF file - 240K, Effects of D-mannose on ALL cytotoxicity induced by equimolar concentrations of 2-DG and 2-FDG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6068ab1d7f5a70648f9c7776c2e84381
https://doi.org/10.1158/1541-7786.22517755
https://doi.org/10.1158/1541-7786.22517755
Autor:
Julio C. Barredo, Theodore J. Lampidis, Guy J. Leclerc, Gilles M. Leclerc, Jianfeng Du, Jeffim N. Kuznetsov, Joanna DeSalvo
PDF file - 415K, Inhibition of mTOR with CCI-779 does not protect ALL cells from 2-DG-cytotoxicity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03fb21591c4afc8c7f1cd1cd659f8a08
https://doi.org/10.1158/1541-7786.22517767
https://doi.org/10.1158/1541-7786.22517767
Autor:
Julio C. Barredo, Theodore J. Lampidis, Guy J. Leclerc, Gilles M. Leclerc, Jianfeng Du, Jeffim N. Kuznetsov, Joanna DeSalvo
PDF file - 385K, The AMP analogue AICAr does not significantly affect 2-DG-induced cytotoxicity in ALL cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a6223cb2427579dd699cbf6bf9ddbd5
https://doi.org/10.1158/1541-7786.22517764
https://doi.org/10.1158/1541-7786.22517764
Autor:
Guy Jacques LeClerc, Helena Gomes Dos Santos, Guangyan Sun, Ramin Shiekhattar, Julio C Barredo
Publikováno v:
Blood. 140:8770-8771
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7d41a894695f9b08a875a896641eaad
https://doi.org/10.1182/blood-2022-167271
https://doi.org/10.1182/blood-2022-167271
Autor:
Jessica A. Pollard, Victor M. Aquino, Leigh Marcus, Weili Sun, Blythe Thomson, Naomi J. Winick, Phoenix A. Ho, Anupam Verma, Julio C. Barredo, Rajen Mody, Michael J. Burke, Theodore W. Laetsch, John Goldberg, Rebecca Gardner, Wendy Tcheng, Cecilia Fu, Thomas Manley, Paul S. Gaynon, Richard Sposto, Julie Park, Yoav H. Messinger, Sima Jeha, Julia Glade Bender, Maria Luisa Sulis, Nobuko Hijiya
Publikováno v:
Pediatric Hematology and Oncology. 37:465-474
Background: Panobinostat demonstrates activity against pediatric cancers in vitro. A phase I trial in children with refractory hematologic malignancies was conducted. Study design: The trial evalua...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::691e55398c8122c94fd4d7e88ce5ca1d
https://doi.org/10.1080/08880018.2020.1752869
https://doi.org/10.1080/08880018.2020.1752869