Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Juliette Léon"'
FoxP3+CD4+ regulatory T cells (Tregs), essential for immunologic and organismal homeostasis, have diverse functions and corresponding gene expression programs. How the many controlling transcription factors (TFs) organize to determine Treg identity a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf0c93f52cdfe3ba809598be942029c2
https://doi.org/10.1101/2023.05.18.541358
https://doi.org/10.1101/2023.05.18.541358
Autor:
Nathalie Chavarot, Michael Padden, Lucile Amrouche, Stéphanie Malard, Anne Scemla, Rebecca Sberro-Soussan, Juliette Léon, Christophe Legendre, Jean Paul Duong, Julien Zuber, Dany Anglicheau, Marion Rabant, Pierre Isnard
Publikováno v:
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant SurgeonsREFERENCES. 22(12)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cd621c9893cb9506605a7582232c7ab
https://pubmed.ncbi.nlm.nih.gov/35959598
https://pubmed.ncbi.nlm.nih.gov/35959598
Autor:
Juliette Leon, Kaitavjeet Chowdhary, Wenxiang Zhang, Ricardo N. Ramirez, Isabelle André, Sun Hur, Diane Mathis, Christophe Benoist
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 113018- (2023)
Summary: Mutations of the transcription factor FoxP3 in patients with “IPEX” (immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome) disrupt regulatory T cells (Treg), causing an array of multiorgan autoimmunity. To understand
Externí odkaz:
https://doaj.org/article/f923e572644745f8abd0faaa4e0297aa
Autor:
Baptiste Lamarthée, Armance Marchal, Soëli Charbonnier, Tifanie Blein, Juliette Leon, Emmanuel Martin, Lucas Rabaux, Katrin Vogt, Matthias Titeux, Marianne Delville, Hélène Vinçon, Emmanuelle Six, Nicolas Pallet, David Michonneau, Dany Anglicheau, Christophe Legendre, Jean-Luc Taupin, Ivan Nemazanyy, Birgit Sawitzki, Sylvain Latour, Marina Cavazzana, Isabelle André, Julien Zuber
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Chimeric antigen receptor engineering in T cells has been shown to be of great potential therapeutic benefit in a range of immune pathologies, although the functionality of such cell therapies can be limited due to tonic signalling and the induction
Externí odkaz:
https://doaj.org/article/ff953c0676e145dc93bb84de2244c04f
Autor:
Judith Olejnik, Juliette Leon, Daniel Michelson, Kaitavjeet Chowdhary, Silvia Galvan-Pena, Christophe Benoist, Elke Mühlberger, Adam J. Hume
Publikováno v:
Pathogens, Vol 12, Iss 2, p 342 (2023)
Technologies that facilitate the bulk sequencing of small numbers of cells as well as single-cell RNA sequencing (scRNA-seq) have aided greatly in the study of viruses as these analyses can be used to differentiate responses from infected versus byst
Externí odkaz:
https://doaj.org/article/be575cbc19404d78a405131374231769
Autor:
María José Pérez-Sáez, Audrey Uffing, Juliette Leon, Naoka Murakami, Andreia Watanabe, Thiago J. Borges, Venkata S. Sabbisetti, Pamela Cureton, Victoria Kenyon, Leigh Keating, Karen Yee, Carla Aline Fernandes Satiro, Gloria Serena, Friedhelm Hildebrandt, Cristian V. Riella, Towia A. Libermann, Minxian Wang, Julio Pascual, Joseph V. Bonventre, Paolo Cravedi, Alessio Fasano, Leonardo V. Riella
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/410fb119815f4d7681fd9c1e61368be0
Autor:
María José Pérez-Sáez, Audrey Uffing, Juliette Leon, Naoka Murakami, Andreia Watanabe, Thiago J. Borges, Venkata S. Sabbisetti, Pamela Cureton, Victoria Kenyon, Leigh Keating, Karen Yee, Carla Aline Fernandes Satiro, Gloria Serena, Friedhelm Hildebrandt, Cristian V. Riella, Towia A. Libermann, Minxian Wang, Julio Pascual, Joseph V. Bonventre, Paolo Cravedi, Alessio Fasano, Leonardo V. Riella
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Kidney disease affects 10% of the world population and is associated with increased mortality. Steroid-resistant nephrotic syndrome (SRNS) is a leading cause of end-stage kidney disease in children, often failing standard immunosuppression. Here, we
Externí odkaz:
https://doaj.org/article/c2cf763eb57f4a9db8902dcef71c6e24
Autor:
Nicolas S. Merle, Juliette Leon, Victoria Poillerat, Anne Grunenwald, Idris Boudhabhay, Samantha Knockaert, Tania Robe-Rybkine, Carine Torset, Matthew C. Pickering, Sophie Chauvet, Veronique Fremeaux-Bacchi, Lubka T. Roumenina
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Intravascular hemolysis of any cause can induce acute kidney injury (AKI). Hemolysis-derived product heme activates the innate immune complement system and contributes to renal damage. Therefore, we explored the role of the master complement regulato
Externí odkaz:
https://doaj.org/article/46b034fe48a84de9a00b0c1dc8408830
Autor:
Victoria Poillerat, Thomas Gentinetta, Juliette Leon, Andreas Wassmer, Monika Edler, Carine Torset, Dandan Luo, Gerald Tuffin, Lubka T. Roumenina
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Hemopexin is the main plasmatic scavenger of cell-free heme, released in the context of intravascular hemolysis or major cell injury. Heme is indispensable for the oxygen transport by hemoglobin but when released outside of the erythrocytes it become
Externí odkaz:
https://doaj.org/article/5db3b057425947cf92197b11d0d2704a
Autor:
Juliette Leon, María José Pérez-Sáez, Audrey Uffing, Naoka Murakami, Andreia Watanabe, Pamela Cureton, Victoria Kenyon, Leigh Keating, Karen Yee, Carla Aline Fernandes Satiro, Bryant Yu, Joseph V. Bonventre, Alessio Fasano, Leonardo V. Riella
Publikováno v:
Kidney International Reports, Vol 3, Iss 4, Pp 851-860 (2018)
Introduction: Steroid-resistant nephrotic syndrome (SRNS) affects both children and adults and has a high rate of progression to end-stage renal disease. Although a subset of patients have well-characterized genetic mutation(s), in the majority of ca
Externí odkaz:
https://doaj.org/article/e07b2c35d1d641efaa4258c6f9e0db35