Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Juliette J. Kahle"'
Autor:
Juliette J Kahle, George P Souroullas, Peng Yu, Fabian Zohren, Yoontae Lee, Chad A Shaw, Huda Y Zoghbi, Margaret A Goodell
Publikováno v:
PLoS Genetics, Vol 9, Iss 3, p e1003359 (2013)
Hematopoietic stem cells (HSCs) are rare quiescent cells that continuously replenish the cellular components of the peripheral blood. Observing that the ataxia-associated gene Ataxin-1-like (Atxn1L) was highly expressed in HSCs, we examined its role
Externí odkaz:
https://doaj.org/article/29ae8d66add846f0880c2c6451b2ae28
Publikováno v:
Toxicological Sciences. 152:264-272
Biomarker measurements that reliably correlate with tissue injury and that can be measured within accessible biofluids offer benefits in terms of cost, time, and convenience when assessing chemical and drug-induced toxicity in model systems or human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec74051ffae9f696ab9916879d395473
https://doi.org/10.1093/toxsci/kfw090
https://doi.org/10.1093/toxsci/kfw090
Publikováno v:
ISEE Conference Abstracts. 2018
While changes in lung function (LF) due to ozone (OZ) exposure are well-documented in healthy populations, potential sources of response heterogeneity, like stress, remain uncharacterized. Though e...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46f054e39560a1d5fae819e4fb34cfe9
https://doi.org/10.1289/isesisee.2018.o01.03.64
https://doi.org/10.1289/isesisee.2018.o01.03.64
Autor:
Milton J. Finegold, Huda Y. Zoghbi, John D. Fryer, Juan Crespo-Barreto, Harry T. Orr, Aaron B. Bowman, Jeong Soo Hong, Farrah Kheradmand, Juliette J. Kahle, Hyojin Kang, Yoontae Lee, Yan Gao
Publikováno v:
Developmental Cell. 21:746-757
Summary Although expansion of CAG repeats in ATAXIN1 ( ATXN1 ) causes Spinocerebellar ataxia type 1, the functions of ATXN1 and ATAXIN1-Like (ATXN1L) remain poorly understood. To investigate the function of these proteins, we generated and characteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87256c63cad9dff5878c9fe20afa5219
https://doi.org/10.1016/j.devcel.2011.08.017
https://doi.org/10.1016/j.devcel.2011.08.017
Autor:
Lucas M. Neas, Michael C. Madden, Martin Case, Robert B. Devlin, Juliette J. Kahle, Michael T. Schmitt, David Diaz-Sanchez
Publikováno v:
Environmental Health Perspectives
Background: Trends in climate suggest that extreme weather events such as heat waves will become more common. High levels of the gaseous pollutant ozone are associated with elevated temperatures. Ozone has been associated with respiratory diseases as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93fba31d53b10b7a090e41f43d2af8c7
https://pubmed.ncbi.nlm.nih.gov/25514459
https://pubmed.ncbi.nlm.nih.gov/25514459
Autor:
Harry T. Orr, Karthik Chirala, Hyoungseok Ju, Hiroshi Kokubu, Ronald Richman, Juliette J. Kahle, Janghoo Lim, Tiffany W. Todd, Soeun Kim, Huda Y. Zoghbi
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 33(22)
Polyglutamine diseases are dominantly inherited neurodegenerative diseases caused by an expansion of a CAG trinucleotide repeat encoding a glutamine tract in the respective disease-causing proteins. Extensive studies have been performed to unravel di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f842b0e18ba99551d8af45e02b06845
https://pubmed.ncbi.nlm.nih.gov/23719801
https://pubmed.ncbi.nlm.nih.gov/23719801
Autor:
Margaret A. Goodell, Juliette J. Kahle, Huda Y. Zoghbi, Chad A. Shaw, Peng Yu, George P. Souroullas, Yoontae Lee, Fabian Zohren
Publikováno v:
PLoS Genetics, Vol 9, Iss 3, p e1003359 (2013)
PLoS Genetics
PLoS Genetics
Hematopoietic stem cells (HSCs) are rare quiescent cells that continuously replenish the cellular components of the peripheral blood. Observing that the ataxia-associated gene Ataxin-1-like (Atxn1L) was highly expressed in HSCs, we examined its role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3d616827752755161f20ae09b410c33
http://europepmc.org/articles/PMC3610904?pdf=render
http://europepmc.org/articles/PMC3610904?pdf=render
Autor:
Anna Fisher, Juliette J. Kahle, David Diaz-Sanchez, Kelly E. Duncan, Michael T. Schmitt, Beena Vallanat, Robert B. Devlin
Publikováno v:
B110. GENOMICS, METABOLOMICS, AND EPIGENETICS IN LUNG DISEASE: LATE BREAKING ABSTRACTS.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17b0a236377fe3f9341611ece4d6172c
https://doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a6834
https://doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a6834
Autor:
Yung C. Lam, Harry T. Orr, Juliette J. Kahle, Paymaan Jafar-Nejad, Huda Y. Zoghbi, Hung Kai Chen, Ronald Richman, Aaron B. Bowman, Rodney C. Samaco, John D. Fryer
Publikováno v:
Nature genetics. 39(3)
Spinocerebellar ataxia type 1 (SCA1) is a dominantly inherited neurodegenerative disease caused by expansion of a glutamine tract in ataxin-1 (ATXN1). SCA1 pathogenesis studies support a model in which the expanded glutamine tract causes toxicity by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9903c725d18b614b83f426b40e0a2666
https://pubmed.ncbi.nlm.nih.gov/17322884
https://pubmed.ncbi.nlm.nih.gov/17322884