Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Juliette D. Godin"'
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
Heterogeneous nuclear ribonucleoproteins (hnRNPs) constitute a family of multifunctional RNA-binding proteins able to process nuclear pre-mRNAs into mature mRNAs and regulate gene expression in multiple ways. They comprise at least 20 different membe
Externí odkaz:
https://doaj.org/article/98b9dedf7c4647f3a06f4e77d04f4e29
Autor:
José Rivera Alvarez, Laure Asselin, Peggy Tilly, Roxane Benoit, Claire Batisse, Ludovic Richert, Julien Batisse, Bastien Morlet, Florian Levet, Noémie Schwaller, Yves Mély, Marc Ruff, Anne-Cécile Reymann, Juliette D. Godin
Publikováno v:
Cell Reports, Vol 42, Iss 7, Pp 112744- (2023)
Summary: Completion of neuronal migration is critical for brain development. Kif21b is a plus-end-directed kinesin motor protein that promotes intracellular transport and controls microtubule dynamics in neurons. Here we report a physiological functi
Externí odkaz:
https://doaj.org/article/b4ba44d3e5c544848a643fbb11dedca7
Autor:
Laure Asselin, José Rivera Alvarez, Solveig Heide, Camille S. Bonnet, Peggy Tilly, Hélène Vitet, Chantal Weber, Carlos A. Bacino, Kristin Baranaño, Anna Chassevent, Amy Dameron, Laurence Faivre, Neil A. Hanchard, Sonal Mahida, Kirsty McWalter, Cyril Mignot, Caroline Nava, Agnès Rastetter, Haley Streff, Christel Thauvin-Robinet, Marjan M. Weiss, Gladys Zapata, Petra J. G. Zwijnenburg, Frédéric Saudou, Christel Depienne, Christelle Golzio, Delphine Héron, Juliette D. Godin
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Kinesins regulate intracellular transport and microtubule dynamics. Here, the authors show that KIF21B variants in humans associate with corpus callosum agenesis and microcephaly. Using mice and zebrafish, they showed the cellular mechanisms altered
Externí odkaz:
https://doaj.org/article/85fa7763d73b4163bd09f2ee5a5c74a8
Autor:
Ekaterina L. Ivanova, Johan G. Gilet, Vadym Sulimenko, Arnaud Duchon, Gabrielle Rudolf, Karen Runge, Stephan C. Collins, Laure Asselin, Loic Broix, Nathalie Drouot, Peggy Tilly, Patrick Nusbaum, Alexandre Vincent, William Magnant, Valerie Skory, Marie-Christine Birling, Guillaume Pavlovic, Juliette D. Godin, Binnaz Yalcin, Yann Hérault, Pavel Dráber, Jamel Chelly, Maria-Victoria Hinckelmann
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-18 (2019)
New mutations and genes associated with malformations of cortical development keep being identified, yet there is little known about the underlying cellular mechanisms controlling these impairments. Here, authors generate and characterize a heterozyg
Externí odkaz:
https://doaj.org/article/70b73ea35c47483e83ff67156a41b716
Autor:
Giovanni Morelli, Aviel Even, Ivan Gladwyn-Ng, Romain Le Bail, Michal Shilian, Juliette D. Godin, Elise Peyre, Bassem A. Hassan, Arnaud Besson, Jean-Michel Rigo, Miguel Weil, Bert Brône, Laurent Nguyen
Publikováno v:
Cell Reports, Vol 23, Iss 8, Pp 2429-2442 (2018)
Summary: The protein p27Kip1 plays roles that extend beyond cell-cycle regulation during cerebral cortex development, such as the regulation of neuronal migration and neurite branching via signaling pathways that converge on the actin and microtubule
Externí odkaz:
https://doaj.org/article/378b315858594c00bfd8aedf11284e49
Autor:
Marie-Laure Volvert, Pierre-Paul Prévot, Pierre Close, Sophie Laguesse, Sophie Pirotte, James Hemphill, Florence Rogister, Nathalie Kruzy, Rosalie Sacheli, Gustave Moonen, Alexander Deiters, Matthias Merkenschlager, Alain Chariot, Brigitte Malgrange, Juliette D. Godin, Laurent Nguyen
Publikováno v:
Cell Reports, Vol 7, Iss 4, Pp 1168-1183 (2014)
The migration of cortical projection neurons is a multistep process characterized by dynamic cell shape remodeling. The molecular basis of these changes remains elusive, and the present work describes how microRNAs (miRNAs) control neuronal polarizat
Externí odkaz:
https://doaj.org/article/f95d433ec4004531bfdcaf3c545b234e
Autor:
Dhanya Lakshmi Narayanan, José Rivera Alvarez, Peggy Tilly, Michelle C. do Rosario, Vivekananda Bhat, Juliette D. Godin, Anju Shukla
Publikováno v:
Journal of Human Genetics. 67:729-733
Kinesin Family Member 21B (KIF21B) encoded by KIF21B (MIM*608322), belongs to the Kinesin superfamily proteins, which play a key role in microtubule organisation in neuronal dendrites and axons. Recently, heterozygous variants in KIF21B were implicat
Autor:
Jordi Del-Pozo-Rodríguez, Christophe Romier, Peggy Tilly, Elizabeth Ramos-Morales, Thalia Salinas-Giegé, Eric Ennifar, Efil Bayam, Edouard Troesch, Martin Marek, Philippe Wolff, Juliette D. Godin, Laurence Drouard
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2021, 49 (11), pp.6529-6548. ⟨10.1093/nar/gkab436⟩
Nucleic Acids Research, 2021, 49 (11), pp.6529-6548. ⟨10.1093/nar/gkab436⟩
Nucleic acids research
Nucleic Acids Research, Oxford University Press, 2021, 49 (11), pp.6529-6548. ⟨10.1093/nar/gkab436⟩
Nucleic Acids Research, 2021, 49 (11), pp.6529-6548. ⟨10.1093/nar/gkab436⟩
Nucleic acids research
Post-transcriptional modification of tRNA wobble adenosine into inosine is crucial for decoding multiple mRNA codons by a single tRNA. The eukaryotic wobble adenosine-to-inosine modification is catalysed by the ADAT (ADAT2/ADAT3) complex that modifie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3049956f50a214bd85cb77744940af2f
https://hal.archives-ouvertes.fr/hal-03282247/document
https://hal.archives-ouvertes.fr/hal-03282247/document
Autor:
Petra J. G. Zwijnenburg, Kirsty McWalter, Sonal Mahida, Delphine Héron, Frédéric Saudou, Hélène Vitet, Anna Chassevent, José Rivera Alvarez, Carlos A. Bacino, Juliette D. Godin, Christel Thauvin-Robinet, Chantal Weber, Laure Asselin, Caroline Nava, Christelle Golzio, Neil A. Hanchard, Christel Depienne, Peggy Tilly, Camille S. Bonnet, Cyril Mignot, Gladys Zapata, Amy Dameron, Marjan M. Weiss, Solveig Heide, Laurence Faivre, Haley Streff, Agnès Rastetter, Kristin W. Barañano
Publikováno v:
Nature Communications
Nature Communications, Nature Publishing Group, 2020, 11 (1), ⟨10.1038/s41467-020-16294-6⟩
Nature Communications, 11, 1, pp. 1-18
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Nature Communications, 11, 1-18
Asselin, L, Rivera Alvarez, J, Heide, S, Bonnet, C S, Tilly, P, Vitet, H, Weber, C, Bacino, C A, Baranaño, K, Chassevent, A, Dameron, A, Faivre, L, Hanchard, N A, Mahida, S, McWalter, K, Mignot, C, Nava, C, Rastetter, A, Streff, H, Thauvin-Robinet, C, Weiss, M M, Zapata, G, Zwijnenburg, P J G, Saudou, F, Depienne, C, Golzio, C, Héron, D & Godin, J D 2020, ' Mutations in the KIF21B kinesin gene cause neurodevelopmental disorders through imbalanced canonical motor activity ', Nature Communications, vol. 11, no. 1, 2441 . https://doi.org/10.1038/s41467-020-16294-6
Nature Communications, Nature Publishing Group, 2020, 11 (1), ⟨10.1038/s41467-020-16294-6⟩
Nature Communications, 11, 1, pp. 1-18
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Nature Communications, 11, 1-18
Asselin, L, Rivera Alvarez, J, Heide, S, Bonnet, C S, Tilly, P, Vitet, H, Weber, C, Bacino, C A, Baranaño, K, Chassevent, A, Dameron, A, Faivre, L, Hanchard, N A, Mahida, S, McWalter, K, Mignot, C, Nava, C, Rastetter, A, Streff, H, Thauvin-Robinet, C, Weiss, M M, Zapata, G, Zwijnenburg, P J G, Saudou, F, Depienne, C, Golzio, C, Héron, D & Godin, J D 2020, ' Mutations in the KIF21B kinesin gene cause neurodevelopmental disorders through imbalanced canonical motor activity ', Nature Communications, vol. 11, no. 1, 2441 . https://doi.org/10.1038/s41467-020-16294-6
KIF21B is a kinesin protein that promotes intracellular transport and controls microtubule dynamics. We report three missense variants and one duplication in KIF21B in individuals with neurodevelopmental disorders associated with brain malformations,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2280cfa8349226d6a47d71980798ba85
https://hal.archives-ouvertes.fr/hal-03373809
https://hal.archives-ouvertes.fr/hal-03373809
Autor:
Nathalie Drouot, Patrick Nusbaum, William Magnant, Binnaz Yalcin, Arnaud Duchon, Loic Broix, Jamel Chelly, Valerie Skory, Stephan C. Collins, Maria-Victoria Hinckelmann, Vadym Sulimenko, Yann Herault, Marie-Christine Birling, Juliette D. Godin, Guillaume Pavlovic, Pavel Dráber, Karen Runge, Laure Asselin, Ekaterina L. Ivanova, Gabrielle Rudolf, Peggy Tilly, Alexandre Vincent, Johan G. Gilet
Publikováno v:
Nature Communications
Nature Communications, Nature Publishing Group, 2019, 10 (1), ⟨10.1038/s41467-019-10081-8⟩
Nature Communications, Vol 10, Iss 1, Pp 1-18 (2019)
Nature Communications, 2019, 10 (1), pp.100-110. ⟨10.1038/s41467-019-10081-8⟩
Nature Communications, Nature Publishing Group, 2019, 10 (1), ⟨10.1038/s41467-019-10081-8⟩
Nature Communications, Vol 10, Iss 1, Pp 1-18 (2019)
Nature Communications, 2019, 10 (1), pp.100-110. ⟨10.1038/s41467-019-10081-8⟩
De novo heterozygous missense variants in the γ-tubulin gene TUBG1 have been linked to human malformations of cortical development associated with intellectual disability and epilepsy. Here, we investigated through in-utero electroporation and in-vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7593bcb4ef7889f22fe4f4a6a5b20310
https://hal.archives-ouvertes.fr/hal-02388602
https://hal.archives-ouvertes.fr/hal-02388602