JMJD6 regulates ERα methylation on arginine.

Autor: Coralie Poulard, Juliette Rambaud, Nader Hussein, Laura Corbo, Muriel Le Romancer

Publikováno v: PLoS ONE, Vol 9, Iss 2, p e87982 (2014)

ERα functions are tightly controlled by numerous post-translational modifications including arginine methylation, which is required to mediate the extranuclear functions of the receptor. We report that upon oestrogenic stimulation, JMJD6, the only a

Externí odkaz: https://doaj.org/article/c93275f210f244afbb1176eb82b361df

TIF1β/KAP-1 Is a Coactivator of the Orphan Nuclear Receptor NGFI-B/Nur77

Autor: Juliette Rambaud, Jacques Drouin, Aurelio Balsalobre, Julien Desroches

Publikováno v: Journal of Biological Chemistry. 284:14147-14156

In efforts to define mechanisms of transcriptional activation by the orphan nuclear receptor NGFI-B (Nur77), we identified TIF1beta by mass spectrometry within a nuclear protein complex containing NGFI-B. TIF1beta, also known as KAP-1 (KRAB domain-as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a68fa129055065bc0ee11b8379cee92
https://doi.org/10.1074/jbc.m809023200

LKB1 when associated with methylatedERα is a marker of bad prognosis in breast cancer

Autor: Sylvie Mader, Muriel Le Romancer, Emilie Lavergne, Laura Corbo, Thomas Bachelot, Guila Dayan, Coralie Poulard, Katia Bouchekioua-Bouzaghou, Marc Billaud, Nader Hussein, Isabelle Treilleux, Juliette Rambaud, Sylvie Chabaud

Publikováno v: International Journal of Cancer.

Although the presence of nuclear estrogen receptor is widely used to guide breast cancer therapy, less attention has been paid to the receptor cytoplasmic signaling. Recently, we have shown that this pathway is operative in vivo and is activated in a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e5479e74a588d311e4dc7f1c194d83c9
https://doi.org/10.1002/ijc.28781

JMJD6 regulates ERα methylation on arginine

Autor: Coralie Poulard, Nader Hussein, Laura Corbo, Muriel Le Romancer, Juliette Rambaud

Publikováno v: PLoS ONE
PLoS ONE, Vol 9, Iss 2, p e87982 (2014)

ERα functions are tightly controlled by numerous post-translational modifications including arginine methylation, which is required to mediate the extranuclear functions of the receptor. We report that upon oestrogenic stimulation, JMJD6, the only a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59c42a96a4256f1776fc3228760e07d6
https://pubmed.ncbi.nlm.nih.gov/24498420

Expression levels of estrogen receptor β are modulated by components of the molecular clock

Autor: Juliette Rambaud, Ingemar Pongratz, Ingrid Masse, Jan-Ake Gustafsson, Wen Cai, Michèle Teboul, Vincent Laudet, Franck Delaunay, Gérard Benoit

Publikováno v: Molecular and Cellular Biology
Molecular and Cellular Biology, American Society for Microbiology, 2008, 28 (2), pp.784-793. ⟨10.1128/MCB.00233-07⟩
Molecular and Cellular Biology, 2008, 28 (2), pp.784-793. ⟨10.1128/MCB.00233-07⟩

International audience; Circadian regulation of gene expression plays a major role in health and disease. The precise role of the circadian system remains to be clarified, but it. is known that circadian proteins generate physiological rhythms in org

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20dedb56cb675c47368feb7da8531a18
https://hal.inrae.fr/hal-02668584