Zobrazeno 1 - 10
of 251
pro vyhledávání: '"Juliette, Hukin"'
Autor:
Craig Erker, Magimairajan Issai Vanan, Valérie Larouche, Liana Nobre, Chantel Cacciotti, Stéphanie Vairy, Shayna Zelcer, Adam Fleming, Eric Bouffet, Nada Jabado, Geneviève Legault, Samuele Renzi, Tara McKeown, Bruce Crooks, Nirav Thacker, Vijay Ramaswamy, Hallie Coltin, Lucie Lafay-Cousin, Sylvia Cheng, Juliette Hukin, Seth Andrew Climans, Mary Jane Lim-Fat, Sarah McKillop, Sarah Lapointe, Mélanie Alves, Julie Bennett, Uri Tabori, Sébastien Perreault
Publikováno v:
Current Oncology, Vol 31, Iss 7, Pp 4022-4029 (2024)
Background: The treatment of BRAF V600E gliomas with BRAF inhibitors (BRAFis) and MEK inhibitors (MEKis) has been increasingly integrated into clinical practice for pediatric low-grade gliomas (PLGGs) and pediatric high-grade gliomas (HGGs). However,
Externí odkaz:
https://doaj.org/article/18a6d0e5930647838048e65c909b0585
Autor:
Rebecca Ronsley, Celine D. Hounjet, Sylvia Cheng, Shahrad Rod Rassekh, Walter J. Duncan, Christopher Dunham, Jane Gardiner, Arvindera Ghag, Jeffrey P. Ludemann, David Wensley, Wingfield Rehmus, Michael A. Sargent, Juliette Hukin
Publikováno v:
Cancer Medicine, Vol 10, Iss 11, Pp 3556-3564 (2021)
Abstract Purpose To describe a series of children with extensive PNF or treatment refractory PLGG treated on a compassionate basis with trametinib. Methods We report on six patients with NF‐1 treated with trametinib on a compassionate basis at Brit
Externí odkaz:
https://doaj.org/article/778056853ba44d84ae5379fbb35ac161
Autor:
Sébastien Perreault, Valérie Larouche, Uri Tabori, Cynthia Hawkin, Sarah Lippé, Benjamin Ellezam, Jean-Claude Décarie, Yves Théoret, Marie-Élaine Métras, Serge Sultan, Édith Cantin, Marie-Ève Routhier, Maxime Caru, Geneviève Legault, Éric Bouffet, Lucie Lafay-Cousin, Juliette Hukin, Craig Erker, Nada Jabado
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-9 (2019)
Abstract Background Pediatric low-grade gliomas (PLGG) are the most frequent brain tumors in children. Up to 50% will be refractory to conventional chemotherapy. It is now known that the majority of PLGG have activation of the MAPK/ERK pathway. The s
Externí odkaz:
https://doaj.org/article/e66eabef1a354091978ff8f6087684a2
Autor:
Julie Bennett, Craig Erker, Lucie Lafay-Cousin, Vijay Ramaswamy, Juliette Hukin, Magimairajan I. Vanan, Sylvia Cheng, Hallie Coltin, Adriana Fonseca, Donna Johnston, Andrea Lo, Shayna Zelcer, Saima Alvi, Lynette Bowes, Josée Brossard, Janie Charlebois, David Eisenstat, Kathleen Felton, Adam Fleming, Nada Jabado, Valérie Larouche, Geneviève Legault, Chris Mpofu, Sébastien Perreault, Mariana Silva, Roona Sinha, Doug Strother, Derek S. Tsang, Beverly Wilson, Bruce Crooks, Ute Bartels
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Primary CNS tumors are the leading cause of cancer-related death in pediatrics. It is essential to understand treatment trends to interpret national survival data. In Canada, children with CNS tumors are treated at one of 16 tertiary care centers. We
Externí odkaz:
https://doaj.org/article/5122a983a5fa4125af8bc53e72e2cfc2
Autor:
Marita Partanen, Eric Bouffet, Suzanne Laughlin, Douglas Strother, Juliette Hukin, Jovanka Skocic, Kamila Szulc-Lerch, Donald J. Mabbott
Publikováno v:
NeuroImage: Clinical, Vol 20, Iss , Pp 697-704 (2018)
Purpose: Prospective and longitudinal neuroimaging studies of posterior fossa tumors are scarce. Here we evaluate the early changes in white matter and intellectual outcome up to 3 years after diagnosis. Patients and methods: Twenty-two children with
Externí odkaz:
https://doaj.org/article/3e3d11dc93b24ae59b74a8dd182d0941
Autor:
Sandra E. Dunn, Christopher Dunham, Sheila K. Singh, Paul Northcott, Stephen Yip, Rod Rassekh, Juliette Hukin, Ash Singhal, Michael D. Taylor, Eric Bouffet, Vijay Ramaswamy, Cynthia Hawkins, Aru Narendran, Katrina O'Halloran, Chitra Venugopal, Abbas Fotovati, Rachel Berns, Mary Rose Pambid, Branavan Manoranjan, Colleen Foster, Cathy Lee, Joanna Triscott
Medulloblastoma is the most common malignant brain tumor in children. This disease is heterogeneous and is composed of four subtypes of medulloblastoma [WNT, Sonic Hedgehog (SHH), Group 3, and Group 4]. An immediate goal is to identify novel molecula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2676c0f11180d32a7b8ade9835657025
https://doi.org/10.1158/0008-5472.c.6505601
https://doi.org/10.1158/0008-5472.c.6505601
Autor:
Sandra E. Dunn, Christopher Dunham, Sheila K. Singh, Paul Northcott, Stephen Yip, Rod Rassekh, Juliette Hukin, Ash Singhal, Michael D. Taylor, Eric Bouffet, Vijay Ramaswamy, Cynthia Hawkins, Aru Narendran, Katrina O'Halloran, Chitra Venugopal, Abbas Fotovati, Rachel Berns, Mary Rose Pambid, Branavan Manoranjan, Colleen Foster, Cathy Lee, Joanna Triscott
PDF file - 80K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1105923776f2fa6159acbf1c2f1d4367
https://doi.org/10.1158/0008-5472.22400492.v1
https://doi.org/10.1158/0008-5472.22400492.v1
Autor:
Sandra E. Dunn, Christopher Dunham, Sheila K. Singh, Paul Northcott, Stephen Yip, Rod Rassekh, Juliette Hukin, Ash Singhal, Michael D. Taylor, Eric Bouffet, Vijay Ramaswamy, Cynthia Hawkins, Aru Narendran, Katrina O'Halloran, Chitra Venugopal, Abbas Fotovati, Rachel Berns, Mary Rose Pambid, Branavan Manoranjan, Colleen Foster, Cathy Lee, Joanna Triscott
PDF file - 685K, Supplementary Table S1. Summary of the pediatric MB patients included in the study Discovery cohort. Supplementary Table S2. Summary of the pediatric MB patients included in the study Validation cohort. Supplementary Table S3. PAM cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a19d6b4ff4989b69f799a74f683b628
https://doi.org/10.1158/0008-5472.22400489
https://doi.org/10.1158/0008-5472.22400489
Autor:
Craig Erker, Martin Mynarek, Simon Bailey, Claire M. Mazewski, Lorena Baroni, Maura Massimino, Juliette Hukin, Dolly Aguilera, Andrea M. Cappellano, Vijay Ramaswamy, Alvaro Lassaletta, Sébastien Perreault, Cassie N. Kline, Revathi Rajagopal, George Michaiel, Michal Zapotocky, Vicente Santa-Maria Lopez, Andres Morales La Madrid, Chantel Cacciotti, Eric S. Sandler, Lindsey M. Hoffman, Darren Klawinski, Sara Khan, Ralph Salloum, Anna L. Hoppmann, Valérie Larouche, Kathleen Dorris, Helen Toledano, Stephen W. Gilheeney, Mohamed S. Abdelbaki, Beverly Wilson, Derek S. Tsang, Jeffrey Knipstein, Michal Yalon Oren, Shafqat Shah, Jeffrey C. Murray, Kevin F. Ginn, Zhihong J. Wang, Gudrun Fleischhack, Denise Obrecht, Svenja Tonn, Virginia L. Harrod, Kara Matheson, Bruce Crooks, Douglas R. Strother, Kenneth J. Cohen, Jordan R. Hansford, Sabine Mueller, Ashley Margol, Amar Gajjar, Girish Dhall, Jonathan L. Finlay, Paul A. Northcott, Stefan Rutkowski, Steven C. Clifford, Giles Robinson, Eric Bouffet, Lucie Lafay-Cousin
PURPOSE Infant and young childhood medulloblastoma (iMB) is usually treated without craniospinal irradiation (CSI) to avoid neurocognitive late effects. Unfortunately, many children relapse. The purpose of this study was to assess salvage strategies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e1c84196b9b4ebe9f95cd02adcf4b70
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85151312540
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85151312540
Autor:
Wingfield Rehmus, Walter J. Duncan, Rebecca Ronsley, Shahrad Rod Rassekh, Arvindera Ghag, Jane Gardiner, Celine D Hounjet, Juliette Hukin, Michael A. Sargent, Sylvia Cheng, Christopher Dunham, Jeffrey P. Ludemann, David Wensley
Publikováno v:
Cancer Medicine, Vol 10, Iss 11, Pp 3556-3564 (2021)
Cancer Medicine
Cancer Medicine
Purpose To describe a series of children with extensive PNF or treatment refractory PLGG treated on a compassionate basis with trametinib. Methods We report on six patients with NF‐1 treated with trametinib on a compassionate basis at British Colum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d333357b921c7aa583670e75af6fc69
https://doaj.org/article/778056853ba44d84ae5379fbb35ac161
https://doaj.org/article/778056853ba44d84ae5379fbb35ac161