Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Julieta Gradinaru"'
Autor:
Thomas R. Ward, Jérôme Collot, Julieta Gradinaru, Andreas Loosli, Myriem Skander, Christophe Letondor, Edith Joseph, Gérard Klein
Publikováno v:
CHIMIA, Vol 57, Iss 10 (2003)
With the aim of exploring the role of the second coordination sphere in enantioselective catalysis, achiral organometallic catalyst precursors are anchored in proteins via non-covalent interactions. A chemogenetic procedure allows the activity and th
Externí odkaz:
https://doaj.org/article/74c836b2c92641868d4c4a204efa3b1a
Autor:
Pierre-Alain Carrupt, Laurent Geiser, Julieta Gradinaru, Dany Spaggiari, Stéphanie Anne Romand, Serge Rudaz
Publikováno v:
European Journal of Pharmaceutical Sciences, Vol. 71 (2015) pp. 35-45
A rapid method for the simultaneous determination of the in vitro activity of the 10 major human liver UDP-glucuronosyltransferase (UGT) enzymes was developed based on the cocktail approach. Specific substrates were first selected for each UGT: etopo
Autor:
Therese Wohlschlager, Alessia Sardo, Tilman Schirmer, Tillmann Heinisch, Claudia Massa, Jeremy M. Zimbron, Julieta Gradinaru, Thomas R. Ward, Marc Creus
Publikováno v:
Chemistry
The mode of action of precious metal anticancer metallodrugs is generally believed to involve DNA as a target. However, the poor specificity of such drugs often requires high doses and leads to undesirable side-effects. With the aim of improving the
Autor:
Anita Ivanova, Thomas R. Ward, Marc Creus, Julien Pierron, Julieta Gradinaru, Ines Hafner, Christophe Malan, Alessia Sardo
Publikováno v:
Angewandte Chemie International Edition. 47:701-705
Palladium in the active site: The incorporation of a biotinylated palladium diphosphine within streptavidin yielded an artificial metalloenzyme for the title reaction (see scheme). Chemogenetic optimization of the catalyst by the introduction of a sp
Publikováno v:
Polyhedron. 25:3417-3426
Three new coordination compounds, [Co3(DH)6] · 24H2O (I), [Co(DH)2Tu2]CF3SO3 (II) and [Co(DH)2Py2]CF3SO3 (III) (where DH− = monoanion of dimethylglyoxime, Py = pyridine, Tu = thiourea), were synthesized starting from Co(CF3SO3)2 · 6H2O as a subst
Autor:
Julieta Gradinaru, Thomas R. Ward, Anita Ivanova, Gérard Klein, François Gilardoni, Untung E. Rusbandi, Nicolas Humbert
Publikováno v:
Angewandte Chemie. 117:7942-7945
The combination of chemical- with genetic-optimization strategies (i.e. chemogenetic) allows the production of artificial hydrogenases based on the biotin–avidin technology. In the spirit of enzymes, second-coordination-sphere interactions between
Publikováno v:
Crystallography Reports. 50:217-223
The asymmetric complex [Ni(HL)]I (where H2 L is pyridine-2,6-dicarbaldehyde-bis(S-methylisothiosemicarbazone)) is synthesized by the [2 + 1] template condensation of S-methylisothiosemicarbazide hydroiodide with pyridine-2,6-dicarbaldehyde in the pre
Autor:
Thomas R. Ward, Andreas Loosli, Julieta Gradinaru, Myriem Skander, Andrea Zocchi, Gérard Klein, Jerome Collot, Jerome Sauser, Nicolas Humbert, François Gilardoni
Publikováno v:
Journal of the American Chemical Society. 126:14411-14418
We report on the generation of artificial metalloenzymes based on the noncovalent incorporation of biotinylated rhodium−diphosphine complexes in (strept)avidin as host proteins. A chemogenetic optimization procedure allows one to optimize the enant
Autor:
Maria A Popovici, Alessandra Forni, David E. Fenton, Julieta Gradinaru, Maria Gdaniec, Yurii A. Simonov, Sandro Zecchin
Publikováno v:
Inorganica Chimica Acta (Testo stamp.) 357 (2004): 2728–2736. doi:10.1016/j.ica.2004.03.008
info:cnr-pdr/source/autori:Gradinaru J., Forni A., Simonov Y., Popovici M., Zecchin S., Gdaniec M., Fenton D.E./titolo:Mononuclear nickel(II) and copper(II) complexes with Schiff base ligands derived from 2,6-diformyl-4-methylphenol and S-methylisothiosemicarbazones/doi:10.1016%2Fj.ica.2004.03.008/rivista:Inorganica Chimica Acta (Testo stamp.)/anno:2004/pagina_da:2728/pagina_a:2736/intervallo_pagine:2728–2736/volume:357
info:cnr-pdr/source/autori:Gradinaru J., Forni A., Simonov Y., Popovici M., Zecchin S., Gdaniec M., Fenton D.E./titolo:Mononuclear nickel(II) and copper(II) complexes with Schiff base ligands derived from 2,6-diformyl-4-methylphenol and S-methylisothiosemicarbazones/doi:10.1016%2Fj.ica.2004.03.008/rivista:Inorganica Chimica Acta (Testo stamp.)/anno:2004/pagina_da:2728/pagina_a:2736/intervallo_pagine:2728–2736/volume:357
Four new square-planar Ni(II) and Cu(II) complexes with [N2O2] binding system were synthesized by metal-directed condensation of 2,6-diformyl-4-methylphenol with benzoyl or acetylacetone mono-S-methylisothiosemicarbazone. Only mononuclear “one-arme
Autor:
Vladimir B. Arion, Julieta Gradinaru, Olivier Mentré, Yuri A. Simonov, Victor Ch. Kravtsov, Hervé Vezin, Janusz Lipkowski, Nicolai V. Gerbeleu, Jean-Pierre Wignacourt
Publikováno v:
Inorganica Chimica Acta. 328:123-133
The macrocyclisation reaction of 3,3′-(3,6-dioxaoctane-1,8-diyldioxy)-bis(2-hydroxybenzaldehyde) (1) with S-methylisothiosemicarbazide hydroiodide (H2NNC(SCH3)NH2·HI) in the presence of potassium triflate, followed by addition of M(CH3COO)2·nH2O,