Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Julieta Celeste Imperiale"'
Publikováno v:
Journal of Controlled Release. 285:106-141
Despite the wide range of diseases affecting the eye, ocular bioavailability remains a challenge in ophthalmic drug delivery. Nowadays an extensive variety of polymers are being explored to develop colloidal drug carriers which show better performanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::749abbb86570427f1c70ff7e23805aa4
https://doi.org/10.1016/j.jconrel.2018.06.031
https://doi.org/10.1016/j.jconrel.2018.06.031
Autor:
Inbar Schlachet, Mirna Marcela Biglione, Alejandro Sosnik, Marianela Lewicki, Julieta Celeste Imperiale
Publikováno v:
Polymers
Volume 11
Issue 11
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Polymers, Vol 11, Iss 11, p 1862 (2019)
Volume 11
Issue 11
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Polymers, Vol 11, Iss 11, p 1862 (2019)
Interferon alpha (IFN&alpha
) is a protein drug used to treat viral infections and cancer diseases. Due to its poor stability in the gastrointestinal tract, only parenteral administration ensures bioavailability, which is associated with severe
) is a protein drug used to treat viral infections and cancer diseases. Due to its poor stability in the gastrointestinal tract, only parenteral administration ensures bioavailability, which is associated with severe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0475d9689644f09a0669c237df63bfc4
https://pubmed.ncbi.nlm.nih.gov/31718060
https://pubmed.ncbi.nlm.nih.gov/31718060
Autor:
Luciana Gualco, Julieta Celeste Imperiale, Roxana Oberkersch, Alejandro Sosnik, Rita Yanina Rasente, Juan Manuel Lázaro-Martínez, Graciela C. Calabrese
Publikováno v:
Carbohydrate Polymers. 144:362-370
Cardiovascular disease is the largest single cause of morbid-mortality in the world. However, there is still no pharmaceutical treatment that directly targets the blood vessel wall instead of just controlling the risk factors. Here, we produced polye
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c95f07cfb95dc8576bd09a85502a33f8
https://doi.org/10.1016/j.carbpol.2016.02.046
https://doi.org/10.1016/j.carbpol.2016.02.046
Autor:
Maya Menaker Raskin, Guillermina Burillo, Gerardo Cedillo, Alejandro Sosnik, Franklin Muñoz-Muñoz, Julieta Celeste Imperiale, Brenda Vázquez-González, Emilio Bucio
Publikováno v:
Colloids and Surfaces B: Biointerfaces. 136:900-907
Thermo-sensitive graft copolymer amphiphiles of chitosan (CS) and poly(N-isopropylacrylamide) (PNiPAAm), CS-g-PNIPAAm, were successfully synthesized by a catalyst-less one-pot gamma (γ)-radiation-assisted free radical polymerization at three differe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6220b7ecdc99c4e14c1586f44fbbdfa
https://doi.org/10.1016/j.colsurfb.2015.10.036
https://doi.org/10.1016/j.colsurfb.2015.10.036
Autor:
Alejandro Sosnik, Pablo Nejamkin, María J. Del Sole, Julieta Celeste Imperiale, Carlos Edmundo Lanusse
Publikováno v:
Biomaterials. 37:383-394
With the advent of the Highly Active Antiretroviral Therapy, the morbidity and the mortality associated to HIV have been considerably reduced. However, 35-40 million people bear the infection worldwide. One of the main causes of therapeutic failure i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc13013a0cbd5d179c84b8c0834bc81e
https://doi.org/10.1016/j.biomaterials.2014.10.026
https://doi.org/10.1016/j.biomaterials.2014.10.026
Autor:
Carolina Andrea Berini, Marianela Lewicki, Julieta Celeste Imperiale, Alejandro Sosnik, Mirna Marcela Biglione, Camila Cánepa
Publikováno v:
Biomacromolecules. 18(10)
Despite the good clinical efficacy of interferon-alpha (IFNα) to treat some types of cancer and viral infections, this biological drug is underused given its severe adverse effects and high dosing parenteral regimens. Aiming to achieve a breakthroug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::105509a9487dfce15af3cb6fd9bfe43d
https://pubmed.ncbi.nlm.nih.gov/28837330
https://pubmed.ncbi.nlm.nih.gov/28837330
Autor:
Alejandro Sosnik, Gabriela Bevilacqua, Paulo de Tarso Vieira e Rosa, Julieta Celeste Imperiale
Publikováno v:
Drug Development and Industrial Pharmacy. 40:1607-1615
This work investigated the production of pure indinavir free base nanoparticles by a supercritical anti-solvent method to improve the drug dissolution in intestine-like medium.To increase the dissolution of the drug by means of a supercritical fluid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36368933e8858c88d28c36ac6fba5fb8
https://doi.org/10.3109/03639045.2013.838581
https://doi.org/10.3109/03639045.2013.838581
Publikováno v:
Expert Opinion on Drug Delivery. 9:303-323
INTRODUCTION: Due to a lack of approved drugs and formulations, children represent the most vulnerable patients. Magistral, unlicensed formulations obtained by the manipulation of solid forms should undergo clinical evaluation to ensure bioequivalenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e079539cc4db0bf9b5942700c4207f7a
https://doi.org/10.1517/17425247.2012.655268
https://doi.org/10.1517/17425247.2012.655268
Publikováno v:
Nanomedicine (London, England). 10(10)
Infectious diseases are a heterogeneous group of maladies that represent a serious burden to healthcare systems worldwide. Most of the available antimicrobial drugs display poor biopharmaceutical properties that compromise their effectiveness. Cyclod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53a5c450830c206f10f8b75c135080dd
https://pubmed.ncbi.nlm.nih.gov/26008196
https://pubmed.ncbi.nlm.nih.gov/26008196
Microparticles (MPs) and nanoparticles (NPs) have received considerable attention for the design of drug delivery systems (DDS) with unique properties owing to the increased surface area and the ability to fine tune the release process. More recently
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8641f039c1e61d38c4670f86ab4aa48
http://www.ingentaconnect.com/content/asp/jbte/2013/00000003/00000001/art00003
http://www.ingentaconnect.com/content/asp/jbte/2013/00000003/00000001/art00003
