Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Juliet O. Obi"'
Autor:
Juliet O. Obi, Mulu Y. Lubula, Gabriel Cornilescu, Amy Henrickson, Kara McGuire, Chiara M. Evans, Margaret Phillips, Samuel P. Boyson, Borries Demeler, John L. Markley, Karen C. Glass
Publikováno v:
Current Research in Structural Biology, Vol 2, Iss , Pp 104-115 (2020)
Bromodomain-containing proteins are often part of chromatin-modifying complexes, and their activity can lead to altered expression of genes that drive cancer, inflammation and neurological disorders in humans. Bromodomain-PHD finger protein 1 (BRPF1)
Externí odkaz:
https://doaj.org/article/373be060f02e4b3cb3c3da481b1aace9
Publikováno v:
Tropical Medicine and Infectious Disease, Vol 6, Iss 4, p 180 (2021)
Dengue is the most prevalent arthropod-borne viral disease worldwide and affects approximately 2.5 billion people living in over 100 countries. Increasing geographic expansion of Aedes aegypti mosquitoes (which transmit the virus) has made dengue a g
Externí odkaz:
https://doaj.org/article/0752c182e2c34c55a7ba779a08ed2a9a
Autor:
Haarin Chun, James H. Kurasawa, Philip Olivares, Ekaterina S. Marakasova, Svetlana A. Shestopal, Gabriela U. Hassink, Elena Karnaukhova, Mary Migliorini, Juliet O. Obi, Ally K. Smith, Patrick L. Wintrode, Prasannavenkatesh Durai, Keunwan Park, Daniel Deredge, Dudley K. Strickland, Andrey G. Sarafanov
Publikováno v:
Journal of Thrombosis and Haemostasis. 20:2255-2269
Deficiency in blood coagulation factor VIII (FVIII) results in life-threating bleeding (hemophilia A) treated by infusions of FVIII concentrates. To improve disease treatment, FVIII has been modified to increase its plasma half-life, which requires u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbe192fa0a6be1b8e8c0b22fd5c2adbb
https://doi.org/10.1111/jth.15817
https://doi.org/10.1111/jth.15817
Autor:
Erik Klontz, Juliet O. Obi, Yajing Wang, Gabrielle Glendening, Jahid Carr, Constantine Tsibouris, Sahthi Buddula, Shreeram Nallar, Alexei S. Soares, Dorothy Beckett, Jasmina S. Redzic, Elan Eisenmesser, Cheyenne Palm, Katrina Schmidt, Alexis H. Scudder, Trinity Obiorah, Kow Essuman, Jeffrey Milbrandt, Aaron Diantonio, Krishanu Ray, Daniel Deredge, M LD. Snyder, Greg A. Snyder
Toll-like and Interleukin-1/18 receptor resistance (TIR) domain-containing proteins function as important signaling and immune regulatory molecules. TIR domain-containing proteins identified in eukaryotic and prokaryotic species also exhibit NAD+ hyd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95374451370e60151b3cff10b9ddcf36
https://doi.org/10.1101/2023.05.19.541320
https://doi.org/10.1101/2023.05.19.541320
Autor:
Mulu Y. Lubula, Margaret Phillips, Gabriel Cornilescu, Juliet O. Obi, Karen C. Glass, Samuel P. Boyson, John L. Markley, Amy Henrickson, Chiara M. Evans, Kara McGuire, Borries Demeler
Publikováno v:
Current Research in Structural Biology, Vol 2, Iss, Pp 104-115 (2020)
Curr Res Struct Biol
Curr Res Struct Biol
Bromodomain-containing proteins are often part of chromatin-modifying complexes, and their activity can lead to altered expression of genes that drive cancer, inflammation and neurological disorders in humans. Bromodomain-PHD finger protein 1 (BRPF1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89bf6d9c227e0c9391b055a21403786e
http://www.sciencedirect.com/science/article/pii/S2665928X20300106
http://www.sciencedirect.com/science/article/pii/S2665928X20300106
Publikováno v:
Biophysical Journal. 122:220a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::acb587d269268484510ee995e98b64a7
https://doi.org/10.1016/j.bpj.2022.11.1309
https://doi.org/10.1016/j.bpj.2022.11.1309
Autor:
Alex E. Sestok, Janae B. Brown, Juliet O. Obi, Sean M. O’Sullivan, Elsa D. Garcin, Daniel J. Deredge, Aaron T. Smith
Publikováno v:
Journal of Biological Chemistry
Journal of Biological Chemistry, 2022, 298 (4), pp.101808. ⟨10.1016/j.jbc.2022.101808⟩
Journal of Biological Chemistry, 2022, 298 (4), pp.101808. ⟨10.1016/j.jbc.2022.101808⟩
International audience; Iron is an essential element for nearly all organisms, and under anoxic and/or reducing conditions, Fe2+ is the dominant form of iron available to bacteria. The ferrous iron transport (Feo) system is the primary prokaryotic Fe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f27c210d3dac2aff2f9e074b8b8c94be
https://pubmed.ncbi.nlm.nih.gov/35271852
https://pubmed.ncbi.nlm.nih.gov/35271852
Autor:
Janae B. Brown, Aaron T. Smith, Daniel Deredge, Juliet O. Obi, Sean M. O’Sullivan, Elsa D. Garcin, Alex E. Sestok
Iron is an essential element for nearly all organisms, and under anoxic and/or reducing conditions, Fe2+ is the dominant form of iron available to bacteria. The ferrous iron transport (Feo) system has been identified as the primary prokaryotic Fe2+ i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46174f6dda505608351d2cf8b13bf830
https://doi.org/10.1101/2021.09.29.462438
https://doi.org/10.1101/2021.09.29.462438
Publikováno v:
Tropical Medicine and Infectious Disease
Tropical Medicine and Infectious Disease, Vol 6, Iss 180, p 180 (2021)
Tropical Medicine and Infectious Disease, Vol 6, Iss 180, p 180 (2021)
Dengue is the most prevalent arthropod-borne viral disease worldwide and affects approximately 2.5 billion people living in over 100 countries. Increasing geographic expansion of Aedes aegypti mosquitoes (which transmit the virus) has made dengue a g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3ce13464881c59a6d6f1d81e234c030
http://europepmc.org/articles/PMC8544673
http://europepmc.org/articles/PMC8544673
Autor:
Juliet O. Obi, Keiko Maekawa, Karen C. Glass, Sonia Parikh, Qinghai Zhang, Manish B. Shah, Chiara M. Evans
Publikováno v:
Mol Pharmacol
The human CYP2C9 plays a crucial role in the metabolic clearance of a wide range of clinical therapeutics. The *2 allele is a prevalent genetic variation in CYP2C9 that is found in various populations. A marked reduction of catalytic activity toward
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8be8903328728f0b4607f43f474fb85c
https://pubmed.ncbi.nlm.nih.gov/32938720
https://pubmed.ncbi.nlm.nih.gov/32938720