Factors predicting mortality in hospitalised HIV-negative children with lower-chest-wall indrawing pneumonia and implications for management.

Autor: Katherine E Gallagher, Juliet O Awori, Maria D Knoll, Julia Rhodes, Melissa M Higdon, Laura L Hammitt, Christine Prosperi, Henry C Baggett, W Abdullah Brooks, Nicholas Fancourt, Daniel R Feikin, Stephen R C Howie, Karen L Kotloff, Milagritos D Tapia, Orin S Levine, Shabir A Madhi, David R Murdoch, Katherine L O'Brien, Donald M Thea, Vicky L Baillie, Bernard E Ebruke, Alice Kamau, David P Moore, Lawrence Mwananyanda, Emmanuel O Olutunde, Phil Seidenberg, Samba O Sow, Somsak Thamthitiwat, J Anthony G Scott, PERCH Study Group

Publikováno v: PLoS ONE, Vol 19, Iss 3, p e0297159 (2024)

IntroductionIn 2012, the World Health Organization revised treatment guidelines for childhood pneumonia with lower chest wall indrawing (LCWI) but no 'danger signs', to recommend home-based treatment. We analysed data from children hospitalized with

Externí odkaz: https://doaj.org/article/826fb1c750b543528c052395d8cfd435

Epidemiology of the Rhinovirus (RV) in African and Southeast Asian Children: A Case-Control Pneumonia Etiology Study

Autor: Vicky L. Baillie, David P. Moore, Azwifarwi Mathunjwa, Henry C. Baggett, Abdullah Brooks, Daniel R. Feikin, Laura L. Hammitt, Stephen R. C. Howie, Maria Deloria Knoll, Karen L. Kotloff, Orin S. Levine, Katherine L. O’Brien, Anthony G. Scott, Donald M. Thea, Martin Antonio, Juliet O. Awori, Amanda J. Driscoll, Nicholas S. S. Fancourt, Melissa M. Higdon, Ruth A. Karron, Susan C. Morpeth, Justin M. Mulindwa, David R. Murdoch, Daniel E. Park, Christine Prosperi, Mohammed Ziaur Rahman, Mustafizur Rahman, Rasheed A. Salaudeen, Pongpun Sawatwong, Somwe Wa Somwe, Samba O. Sow, Milagritos D. Tapia, Eric A. F. Simões, Shabir A. Madhi

Publikováno v: Viruses, Vol 13, Iss 7, p 1249 (2021)

Rhinovirus (RV) is commonly detected in asymptomatic children; hence, its pathogenicity during childhood pneumonia remains controversial. We evaluated RV epidemiology in HIV-uninfected children hospitalized with clinical pneumonia and among community

Externí odkaz: https://doaj.org/article/ee57503233824f0cab1d572ba91f6ba8

Upper Respiratory Tract Co-detection of Human Endemic Coronaviruses and High-density Pneumococcus Associated With Increased Severity Among HIV-Uninfected Children Under 5 Years Old in the PERCH Study

Autor: Grant A. Mackenzie, Laura L. Hammitt, Orin S. Levine, Karen L. Kotloff, Maria Deloria Knoll, Christine Prosperi, Wantana Paveenkittiporn, Juliet O. Awori, Donald M. Thea, Susan C. Morpeth, Vicky L. Baillie, Lawrence Mwananyanda, Steve R C Howie, Henry C. Baggett, David R. Murdoch, J. Anthony G. Scott, Samba O. Sow, Daniel E. Park, Daniel R. Feikin, W. Abdullah Brooks, Katherine L. O'Brien, Charatdao Bunthi, Shabir A. Madhi, Geoffrey Kwenda, Mohammed Ziaur Rahman, David P. Moore, Melissa M Higdon, Martin Antonio, Milagritos D. Tapia, Mustafizur Rahman, Julia Rhodes

Publikováno v: The Pediatric Infectious Disease Journal

Supplemental Digital Content is available in the text.
Background: Severity of viral respiratory illnesses can be increased with bacterial coinfection and can vary by sex, but influence of coinfection and sex on human endemic coronavirus (CoV) s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3590ced93665b25e61572ccef3ed650
https://pubmed.ncbi.nlm.nih.gov/33883479

Digital auscultation in PERCH: Associations with chest radiography and pneumonia mortality in children

Autor: James Chipeta, Louis Peter Githua, David R. Murdoch, Katherine L. O'Brien, Andrea DeLuca, Joshua Kyalo, Charl Verwey, Nicholas Fancourt, Daniel E. Park, James E. West, Daniel R. Feikin, Henry C. Baggett, Donald M. Thea, Maria Deloria Knoll, Orin S. Levine, Stephen R. C. Howie, Eric D. McCollum, W. Abdullah Brooks, Amanda J. Driscoll, Karen L. Kotloff, Dimitra Emmanouilidou, Nora L. Watson, David P. Moore, Bernard E. Ebruke, Melissa M. Higdon, Laura L. Hammitt, Sathapana Naorat, Shabir A. Madhi, Justin M Mulindwa, Christine Prosperi, Christopher Focht, Lokman Hossain, Mounya Elhilali, Yasmin Jahan, Juliet O. Awori, J. Anthony G. Scott, Somchai Chuananon, Ruth A. Karron

Publikováno v: Pediatric pulmonology. 55(11)

Background Whether digitally recorded lung sounds are associated with radiographic pneumonia or clinical outcomes among children in low-income and middle-income countries is unknown. We sought to address these knowledge gaps. Methods We enrolled 1 to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c179116676f7d0d0bfd454fd9b8ca74
https://pubmed.ncbi.nlm.nih.gov/33333631

Association of C-Reactive Protein With Bacterial and Respiratory Syncytial Virus–Associated Pneumonia Among Children Aged <5 Years in the PERCH Study

Autor: Azwifarwi Mudau, Zhenke Wu, Henry C. Baggett, Daniel R. Feikin, W. Abdullah Brooks, Alice Kamau, Rasheed Salaudeen, Juliet O. Awori, Khalequ Zaman, Stephanie Cascio, Peter V. Adrian, Locadiah Kuwanda, Lawrence Mwananyanda, Doli Goswami, James Chipeta, Mengying Li, James Mwansa, Pongpun Sawatwong, Donald M. Thea, Laura L. Hammitt, Hasan Ashraf, David R. Murdoch, Hubert P. Endtz, Julia Rhodes, Charatdao Bunthi, Geoff Kahn, Susan A. Maloney, Trevor P. Anderson, Phil Seidenberg, Stephen R. C. Howie, Uma Onwuchekwa, Amanda J. Driscoll, Somwe Wa Somwe, Shabir A. Madhi, Boubou Tamboura, Maria Deloria Knoll, Grant A. Mackenzie, Daniel E. Park, Pasakorn Akarasewi, Karen L. Kotloff, Jessica McLellan, Nasreen Mahomed, Christine Prosperi, Joanne L. Mitchell, Nana Kourouma, Mamadou Sylla, Orin S. Levine, Micah Silaba Ominde, Eunice M. Machuka, Katherine L. O'Brien, Vicky L. Baillie, Milagritos D. Tapia, Arifin Shamsul, Martin Antonio, Nora L. Watson, Susan C. Morpeth, E Wangeci Kagucia, Mohammed Ziaur Rahman, Nicholas Fancourt, David P. Moore, Sidi Kazungu, Melissa M. Higdon, Andrea DeLuca, Aliou Toure, Geoffrey Kwenda, Scott L. Zeger, Michelle J. Groome, Somsak Thamthitiwat, Angela Karani, Lokman Hossain, Yasmin Jahan, Samba O. Sow, Syed M. A. Zaman, Jane Crawley, Tham T Le, J. Anthony G. Scott, Anek Kaewpan, Somchai Chuananon, Ruth A. Karron, Bernard E. Ebruke, Wei Fu

Publikováno v: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Clinical Infectious Diseases, 64, S378-S386. Oxford University Press

Background Lack of a gold standard for identifying bacterial and viral etiologies of pneumonia has limited evaluation of C-reactive protein (CRP) for identifying bacterial pneumonia. We evaluated the sensitivity and specificity of CRP for identifying

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fdf37d54ff05642eea7729ffe6ab604
https://doi.org/10.1093/cid/cix150