Cell-to-cell transmission of HSV1 in human keratinocytes in the absence of the major entry receptor, nectin1.

Autor: Joanne Kite, Tiffany Russell, Juliet Jones, Gillian Elliott

Publikováno v: PLoS Pathogens, Vol 17, Iss 9, p e1009631 (2021)

Herpes simplex virus 1 (HSV1) infects the stratified epithelia of the epidermis, oral or genital mucosa, where the main cell type is the keratinocyte. Here we have used nTERT human keratinocytes to generate a CRISPR-Cas9 knockout (KO) of the primary

Externí odkaz: https://doaj.org/article/707c6bccb0fd424dabe9431f136496a7

COVID-19: Rapid antigen detection for SARS-CoV-2 by lateral flow assay: A national systematic evaluation of sensitivity and specificity for mass-testing

Autor: Siobhan Campbell, Susan Hopkins, Richard Sedgewick, Kelly Hollier, Wendy Byrne, Ashley Pegg, Scott Nicol, Kimerbley Webster, Suzannah Pegler, Lottie Rawden, Gillian Rodger, Beverley Buck, Richard Clarke, Tom G. Ritter, Sally Hammond, Derrick W. Crook, Sulaksan Panchalingam, Deborah Wright, Victoria Hardy, Kathryn J Saunders, Matthew Catton, Sarah Mckee, Mark Pinkerton, Gloria Calderon, Joanne Waldron, Andrew Harris, Rishab Balaji, Dominic Affron, Penny Carter, Bea Choi, Ian Wickens, Chris D. Turnbull, Elena Hazell, Silvia D'Arcangelo, Tillie Graham, Alex Sienkiewicz, Louise Oliver, Arabella Legard, Freddie Mellor, Rima Colston, Geeta Ghadiali, Ella Baldwin, Stephen W. Wilson, Tim Brooks, Kate Webberley, T Peto, Pam Devall, Jenny Wang, Daniel P. Carter, Elena Turek, Shaolin Chidavaenzi, Gemma Nanson, Kate Allen, James Connolly, Mary-Anne Darby, Caroline Coulson, May Havinden-Williams, Emma Marshall, Mark Driver, Pauline Brown, Beinn Khulusi, Iman Aurfan, Codie Fahey, Zoe Lampshire, Emily A. Protheroe, Antoinette McNulty, Alison Vaughan, T Lockett, Sally-Anne Hurford, Juan Dobaldo Pavon, Rangeni Zinyama, John I. Bell, Toi Neibler, Heena Mistry, Helen Permain, Lorraine Archer, Neil McLeod, Amelia Sterry, Susan Johnston, Alexander Grassam-Rowe, Ruth Johns, Sian Tiley, Olivia Carr, Carly Tibbins, Arro Peace, Christopher H. Logue, Narindar Ghuman, Ellena Badenoch, Carla Bratten, Ashley Price, Patrick Robinson, Sophie Barraclough, Bertie Rowell, Marie Corcoran, Mollie French, Daniel Myers, Emily Eaton, Sophie Moore, Anna Sherkat, Julie Miller, Susan Ridge, Hellen Purnell, Tanzina Chaudary, Juliet Jones, Laura Seeney, Jim Chadwick, Julie Timmins, Sarah Hoosdally, Des Markham, John Vertannes, Sami Tatar, Richard Vipond, Lennard Y. W. Lee, Sara Read, Anita Agasu, Rosaline de Koning, Tegan Gumsley-Read, Ben Holloway, Thomas Knight, Cathy Rowe, Beth Hanney, Herika Willis, Shelha Siddiqui, Aleksander Stawiarski, Kevin K Chau, Ellie Watson, Simon Clark, Babak Afrough, Cara Tomas-Smith, Margaret Broughton-Smith, James O. Robinson, Joy Edwards, Ranoromanana Evans, Thomas Starkey, Anna Gronert, Graham Ellis, Lavanya Sinha, Jane Willcocks, Miriam Avery, Collette Allen, Natasha Ashbridge, Jane Mitchell, Natalie Draper, Anuradha Krishna, Kate Trigg-Hogarth, Bindhu Xavier, Joe Stevens, Leon Peto, Anila Sukumaran, Joseph Gernon, Emma Stanton, Alice Field, Rachel Evans, Vindhya Maripuri, Iftikhar Khan, Justin Liu, Jewel Jones Nwanaforo, Samatha Chilcott, Eloïse Cook, Sharon Kempson, Tom Foord, Lucy Hughes, Vanessa Lucas, Ben Corley, Chris Bridgeman, Grace Westland, David W Eyre, Sally Gordon, Peter Hammond, Kayleigh Collins, Priya Bagga, Gurvinder Gill, Claire Hall, Philippa C Matthews, Dominic Britton, Pauline Derbyshire, Jasmine Gan, Steve Hurdowar, Lloyd Shail, Harry Nuttall, Sheila F Lumley, Becky Evans, Mika Erik Moeser, Dimitris Papoulidis, Lucy Sheppard, Zarina Mirza, Rachel Michel, David Chapman, Kate Ellis, Bassam Hallis, Hannah Fuchs, Jodie Owen, Dawn Clarke, Joanne Henry, Sue Elwell, Rosie Boulton, Vanessa Fenech, Laura Costello, Alison Allanson, Mike Newbury, Prem Perumal, Mary Walters, Angela Bloss, Kate Gilmour, Charles Reynard, Mark A. Ainsworth, Jennifer Smith, Philip Walker, Tim E. A. Peto, Amanda Selassie, Lisa Zeidan, Jane Shallcross, Oliver Topping, Linda Wagstaff, Liam J Peck, Ella Smith, Karen Pearson, Thanh Pham, John Davis, Elizabeth Truelove, Kerry Gibbons, David Tyrrell, David Green, Wendy Osbourne, Anika Goel, Harriet Jackson, Michelle Platton, Daniel Lasserson, Barbara Wilson, Susan Bird, Mark Dolman, Tracy Benford, Joanne Jackman, Marion Evans, Nicole Stoesser, Jackie Sears, Alex Mighiu, Elaine Butcher, Ashley Otter, Akhila Muthuswamy, Tom Fowler, Janet Field, Angela Sweed, Katie Keating-Fedders, Megan Cathrall, Richard Body, Abbie Bown, Gabriella Harker, Richard Clayton, Kim Hicklin, Ant Crook, Sarah Sampson, Sarah Dyas, Cristina Leggio, Hannah Claasen, Rachel Sayers, Louise Woodhead, Carol Beane, Fiona Yelnoorkar, Jake Osbourne, Marina Bishop, Tinashe Kanyowa, Hema Thomas, Ruth Elderfield, H Pickford, Alexandra Rowlands, Patrick Lahert, Kirsten Lee, Ann Sarah Walker, Mark Stockbridge, Deborah F. McKee

Publikováno v: UK COVID-19 Lateral Flow Oversight Team 2021, ' COVID-19 : Rapid antigen detection for SARS-CoV-2 by lateral flow assay: A national systematic evaluation of sensitivity and specificity for mass-testing ', EClinicalMedicine . https://doi.org/10.1016/j.eclinm.2021.100924
EClinicalMedicine

Background Lateral flow device (LFD) viral antigen immunoassays have been developed around the world as diagnostic tests for SARS-CoV-2 infection. They have been proposed to deliver an infrastructure-light, cost-economical solution giving results wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c87b9c21c171152daba6af29c9c6e7c8
https://doi.org/10.1016/j.eclinm.2021.100924

Multiple Posttranscriptional Strategies To Regulate the Herpes Simplex Virus 1 vhs Endoribonuclease

Autor: Katja Ebert-Keel, Julianna Stylianou, Juliet Jones, Kathleen Pheasant, Gillian Elliott, Ashley Franklyn

Publikováno v: Journal of Virology

A myriad of gene expression strategies has been discovered through studies carried out on viruses. This report concerns the regulation of the HSV-1 vhs endoribonuclease, a virus factor that is important for counteracting host antiviral responses by d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0554f75725996b4245fd279965c3a569
https://pubmed.ncbi.nlm.nih.gov/29925667