Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Juliet Crabtree"'
Autor:
Nathan P Corbett, Darren Blimkie, Kevin C Ho, Bing Cai, Darren P Sutherland, Arlene Kallos, Juliet Crabtree, Annie Rein-Weston, Pascal M Lavoie, Stuart E Turvey, Natalie R Hawkins, Steven G Self, Christopher B Wilson, Adeline M Hajjar, Edgardo S Fortuno, Tobias R Kollmann
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e15041 (2010)
Newborns and young infants suffer increased infectious morbidity and mortality as compared to older children and adults. Morbidity and mortality due to infection are highest during the first weeks of life, decreasing over several years. Furthermore,
Externí odkaz:
https://doaj.org/article/f7561129a616468794da1ddc3981c4ab
Autor:
Sjanna B Besteman, Emily Phung, Henriette H M Raeven, Gimano D Amatngalim, Matevž Rumpret, Juliet Crabtree, Rutger M Schepp, Lisa W Rodenburg, Susanna G Siemonsma, Nile Verleur, Rianne van Slooten, Karen Duran, Gijs W van Haaften, Jeffrey M Beekman, Lauren A Chang, Linde Meyaard, Tjomme van der Bruggen, Guy A M Berbers, Nicole Derksen, Stefan Nierkens, Kaitlyn M Morabito, Tracy J Ruckwardt, Evelyn A Kurt-Jones, Douglas Golenbock, Barney S Graham, Louis J Bont
Publikováno v:
The Journal of Infectious Diseases. 226:258-269
Background Recurrent respiratory syncytial virus (RSV) infection requiring hospitalization is rare and the underlying mechanism is unknown. We aimed to determine the role of CD14-mediated immunity in the pathogenesis of recurrent RSV infection. Metho
Autor:
Katherine A. Fitzgerald, Juliana Blin, Juliet Crabtree, Ankit Bhatta, Maninjay K. Atianand, Zhaozhao Jiang
Publikováno v:
J Immunol
Functional peptides encoded by short open reading frames are emerging as important mediators of fundamental biological processes. In this study, we identified a micropeptide produced from a putative long noncoding RNA (lncRNAs) that is important in c
Publikováno v:
Immunol Rev
VI. Monocytes are innate immune cells essential for host protection against malaria. Upon activation, monocytes function to help reduce parasite burden through phagocytosis, cytokine production, and antigen presentation. However, monocytes have also
Autor:
Michael C. Kiritsy, Jacob E. Schrum, Katherine A. Fitzgerald, Juliet Crabtree, George W. Reed, Ricardo T. Gazzinelli, James W. Kazura, Katherine R. Dobbs, Douglas T. Golenbock, Mihai G. Netea, Arlene E. Dent
Publikováno v:
Journal of Immunology, 200, 1243-1248
Journal of Immunology, 200, 4, pp. 1243-1248
Journal of Immunology, 200, 4, pp. 1243-1248
Malarial infection in naive individuals induces a robust innate immune response. In the recently described model of innate immune memory, an initial stimulus primes the innate immune system to either hyperrespond (termed training) or hyporespond (tol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff518ac9d9958c37e1abb4776c08fde4
http://hdl.handle.net/2066/189840
http://hdl.handle.net/2066/189840
Autor:
Ami Yamamoto, Emily C. Baechler, Juliet Crabtree, Yaya Wang, David T. Ewart, Parastoo Fazeli, Erik J. Peterson
Publikováno v:
Arthritis & Rheumatology. 67:2403-2414
Objective Protein tyrosine phosphatase nonreceptor type 22 (PTPN22) is associated with an increased risk of systemic lupus erythematosus (SLE). PTPN22 encodes Lyp, and a disease-associated coding variant bears an R620W substitution (LypW). LypW carri
Publikováno v:
The Journal of infectious diseases. 214(2)
High-affinity-antibody production, T-cell activation, and interferon upregulation all contribute to protective immunity that occurs in humans following influenza immunization. Hematopoietic cell-specific PTPN22 encodes lymphoid phosphatase (Lyp), whi
Autor:
Steven G. Self, Xiu Yu Wang, Francis Thommai, Natalie Hawkins, Jeff Furlong, Tobias R. Kollmann, Christopher B. Wilson, Adeline M. Hajjar, Pascal M. Lavoie, Darren Blimkie, Annie Rein-Weston, Juliet Crabtree, Edgardo S. Fortuno
Publikováno v:
The Journal of Immunology. 183:7150-7160
The human neonate and infant are unduly susceptible to infection with a wide variety of microbes. This susceptibility is thought to reflect differences from adults in innate and adaptive immunity, but the nature of these differences is incompletely c
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0181338 (2017)
PLoS ONE
PLoS ONE
Objectives Influenza infection is a significant cause of respiratory morbidity among pregnant women. Seasonal influenza vaccination engages innate immune receptors to promote protective immunity. A coding polymorphism (R620W) in PTPN22 imparts elevat
Autor:
Darin L. Wiesner, Juliet Crabtree, Judith N. Nielsen, Anna K. Strain, Kirsten Nielsen, Laura H. Okagaki
Publikováno v:
Infection and immunity. 80(11)
Infection with Cryptococcus neoformans begins when desiccated yeast cells or spores are inhaled and lodge in the alveoli of the lungs. A subset of cryptococcal cells in the lungs differentiate into enlarged cells, referred to as titan cells. Titan ce