Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Julien van Grevenynghe"'
Autor:
Marwa Khabir, Matthieu Blanchet, Léna Angelo, Hamza Loucif, Julien van Grevenynghe, Terence Ndonyi Bukong, Patrick Labonté
Publikováno v:
Viruses, Vol 16, Iss 6, p 825 (2024)
A number of research studies, including ours, have spotlighted exosomes as critical facilitators of viral dissemination. While hepatitis B virus (HBV) transmission through exosomes has been studied, the focus on its satellite virus, the hepatitis del
Externí odkaz:
https://doaj.org/article/ea472f8ea1d74bef8d04aa85df7a4eaa
Autor:
Liseth Carmona-Pérez, Xavier Dagenais-Lussier, Linh T. Mai, Tanja Stögerer, Sharada Swaminathan, Stéphane Isnard, Matthew R. Rice, Betsy J. Barnes, Jean-Pierre Routy, Julien van Grevenynghe, Simona Stäger
Publikováno v:
JCI Insight, Vol 8, Iss 13 (2023)
HIV-1 infection is characterized by inflammation and a progressive decline in CD4+ T cell count. Despite treatment with antiretroviral therapy (ART), the majority of people living with HIV (PLWH) maintain residual levels of inflammation, a low degree
Externí odkaz:
https://doaj.org/article/f2823c61a0e14a9e9f33b2d74c271aa6
Autor:
Nazanin Ghahari, Roman Telittchenko, Hamza Loucif, Stephane Isnard, Jean-Pierre Routy, David Olagnier, Julien van Grevenynghe
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 13, p 11018 (2023)
Like other chronic viral infections, HIV-1 persistence inhibits the development of antigen-specific memory T-cells, resulting in the exhaustion of the immune response and chronic inflammation. Autophagy is a major lysosome-dependent mechanism of intr
Externí odkaz:
https://doaj.org/article/c65d24fa70e149538878c1bb68a3deac
Autor:
Hicham Bessaiah, Pravil Pokharel, Hamza Loucif, Merve Kulbay, Charles Sasseville, Hajer Habouria, Sébastien Houle, Jacques Bernier, Éric Massé, Julien Van Grevenynghe, Charles M Dozois
Publikováno v:
PLoS Pathogens, Vol 17, Iss 5, p e1009617 (2021)
Urinary tract infections (UTIs) are a common bacterial infectious disease in humans, and strains of uropathogenic Escherichia coli (UPEC) are the most frequent cause of UTIs. During infection, UPEC must cope with a variety of stressful conditions in
Externí odkaz:
https://doaj.org/article/6c9b600eff714829a7fe3b4a5a54fdb9
Autor:
Xavier Dagenais-Lussier, Hamza Loucif, Hugo Cadorel, Juliette Blumberger, Stéphane Isnard, Mariana Gé Bego, Éric A Cohen, Jean-Pierre Routy, Julien van Grevenynghe, Montreal Primary Infection Study Group
Publikováno v:
PLoS Pathogens, Vol 15, Iss 10, p e1008060 (2019)
The loss of Memory CD4 T-cells (Mem) is a major hallmark of HIV-1 immuno-pathogenesis and occurs early during the first months of primary infection. A lot of effort has been put into understanding the molecular mechanisms behind this loss, yet they s
Externí odkaz:
https://doaj.org/article/6a88ccc083504e91a9ce6a927e3cea70
Autor:
Cherifa Beji, Hamza Loucif, Roman Telittchenko, David Olagnier, Xavier Dagenais-Lussier, Julien van Grevenynghe
Publikováno v:
Viruses, Vol 12, Iss 8, p 875 (2020)
This review examines the impact of cannabinoids on viral infections, as well as its effects on the mitochondria of the nervous and immune system. The paper conveys information about the beneficial and negative impacts of cannabinoids on viral infecti
Externí odkaz:
https://doaj.org/article/e0fb76bcd12e405cbeabd6772aac6c49
Autor:
Xavier Dagenais-Lussier, Hamza Loucif, Armstrong Murira, Xavier Laulhé, Simona Stäger, Alain Lamarre, Julien van Grevenynghe
Publikováno v:
Viruses, Vol 10, Iss 1, p 12 (2017)
Type I interferons (IFN-I) are one of the primary immune defenses against viruses. Similar to all other molecular mechanisms that are central to eliciting protective immune responses, IFN-I expression is subject to homeostatic controls that regulate
Externí odkaz:
https://doaj.org/article/2ae1c49e638a4a17a36db22aefca482d
Autor:
David Olagnier, Alexandre Sze, Samar Bel Hadj, Cindy Chiang, Courtney Steel, Xiaoying Han, Jean-Pierre Routy, Rongtuan Lin, John Hiscott, Julien van Grevenynghe
Publikováno v:
PLoS Pathogens, Vol 10, Iss 12, p e1004575 (2014)
The mechanisms involved in the persistence of activated CD4+ T lymphocytes following primary human T leukemia/lymphoma virus type 1 (HTLV-1) infection remain unclear. Here, we demonstrate that the HTLV-1 Tax oncoprotein modulates phosphorylation and
Externí odkaz:
https://doaj.org/article/dbc7aea3169c4e23b8f97b7b628bf276
Autor:
Liseth Carmona-Perez, Xavier Dagenais-Lussier, Linh Thuy Mai, Tanja Stögerer, Sharada Swaminathan, Stephane Isnard, Matthew R. Rice, Betsy J. Barnes, Jean Pierre Routy, Julien van Grevenynghe, Simona Stager
Publikováno v:
JCI Insight.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::684244ef382cee574f01968b62d23996
https://doi.org/10.1172/jci.insight.167329
https://doi.org/10.1172/jci.insight.167329
Autor:
Martin R. Jakobsen, Jean-Simon Diallo, Anne Louise Hansen, Taha Azad, Luc A. Sabourin, David Jacobs, Manja Idorn, Geneviève Laroche, Julien van Grevenynghe, Renée M. van der Sluis, Glib Maznyi, Jean Seguin, Fanghui Ren, Daniele Di Carlo, Rozanne Arulanandam, Ragunath Singaravelu, Kathy Fu, David Olagnier, Tommy Alain, Christian K. Holm, Søren R. Paludan, John C. Bell, Marceline Côté, John Hiscott, Demi van der Horst, Naziia Kurmasheva, Lena Cassin, Enrico Palermo, Madalina E. Carter-Timofte, Zaid Taha
Publikováno v:
ACS Infectious Diseases
Carter-Timofte, M E, Arulanandam, R, Kurmasheva, N, Fu, K, Laroche, G, Taha, Z, Van Der Horst, D, Cassin, L, Van Der Sluis, R M, Palermo, E, Di Carlo, D, Jacobs, D, Maznyi, G, Azad, T, Singaravelu, R, Ren, F, Hansen, A L, Idorn, M, Holm, C K, Jakobsen, M R, Van Grevenynghe, J, Hiscott, J, Paludan, S R, Bell, J C, Seguin, J, Sabourin, L A, Côté, M, Diallo, J S, Alain, T & Olagnier, D 2021, ' Antiviral Potential of the Antimicrobial Drug Atovaquone against SARS-CoV-2 and Emerging Variants of Concern ', ACS Infectious Diseases, vol. 7, no. 11, pp. 3034-3051 . https://doi.org/10.1021/acsinfecdis.1c00278
Carter-Timofte, M E, Arulanandam, R, Kurmasheva, N, Fu, K, Laroche, G, Taha, Z, Van Der Horst, D, Cassin, L, Van Der Sluis, R M, Palermo, E, Di Carlo, D, Jacobs, D, Maznyi, G, Azad, T, Singaravelu, R, Ren, F, Hansen, A L, Idorn, M, Holm, C K, Jakobsen, M R, Van Grevenynghe, J, Hiscott, J, Paludan, S R, Bell, J C, Seguin, J, Sabourin, L A, Côté, M, Diallo, J S, Alain, T & Olagnier, D 2021, ' Antiviral Potential of the Antimicrobial Drug Atovaquone against SARS-CoV-2 and Emerging Variants of Concern ', ACS Infectious Diseases, vol. 7, no. 11, pp. 3034-3051 . https://doi.org/10.1021/acsinfecdis.1c00278
The antimicrobial medication malarone (atovaquone/proguanil) is used as a fixed-dose combination for treating children and adults with uncomplicated malaria or as chemoprophylaxis for preventing malaria in travelers. It is an inexpensive, efficacious
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dd3972c1e417035d20e6f69542c6ca0
https://pubmed.ncbi.nlm.nih.gov/34658235
https://pubmed.ncbi.nlm.nih.gov/34658235