Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Julien Y Bertrand"'
Autor:
Pietro Cacialli, Christopher B. Mahony, Tim Petzold, Patrizia Bordignon, Anne-Laure Rougemont, Julien Y. Bertrand
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Reactive oxygen species (ROS) are metabolic by-products which in excess can be toxic for hematopoietic stem and progenitor cells (HSPCs). Here the authors show that toxic ROS are transferred by expanding HSPCs to the zebrafish developmental niche via
Externí odkaz:
https://doaj.org/article/d6e3a9bccebb4f0c9f856c6cbade5db4
Autor:
Giuliano Ferrero, Christopher B. Mahony, Eléonore Dupuis, Laurent Yvernogeau, Elodie Di Ruggiero, Magali Miserocchi, Marianne Caron, Catherine Robin, David Traver, Julien Y. Bertrand, Valérie Wittamer
Publikováno v:
Cell Reports, Vol 24, Iss 1, Pp 130-141 (2018)
Summary: Microglia, the tissue-resident macrophages of the CNS, represent major targets for therapeutic intervention in a wide variety of neurological disorders. Efficient reprogramming protocols to generate microglia-like cells in vitro using patien
Externí odkaz:
https://doaj.org/article/172a896c598042bea79e896a8d550db0
Autor:
Maria-Cristina Keightley, Duncan P. Carradice, Judith E. Layton, Luke Pase, Julien Y. Bertrand, Johannes G. Wittig, Aleksandar Dakic, Andrew P. Badrock, Nicholas J. Cole, David Traver, Stephen L. Nutt, Julia McCoey, Ashley M. Buckle, Joan K. Heath, Graham J. Lieschke
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Neutrophils are increased in response to injury and infection but how they form from a common granulocyte-macrophage progenitor is unclear. Here, the authors identify a role for the transcriptional repressor ZBTB11 in zebrafish, which is regulated by
Externí odkaz:
https://doaj.org/article/3c95ab3a3ca641e6961f1263d836b9c2
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
Rare hematopoietic stem cells (HSCs) can self-renew, establish the entire blood system and represent the basis of regenerative medicine applied to hematological disorders. Clinical use of HSCs is however limited by their inefficient expansion ex vivo
Externí odkaz:
https://doaj.org/article/8e81e185b5404528b4bbd92223d9f809
Autor:
Jean-François Denis, Mannekomba R. Diagbouga, Filippo Molica, Aurélie Hautefort, Tanja Linnerz, Masakatsu Watanabe, Sylvain Lemeille, Julien Y. Bertrand, Brenda R. Kwak
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Shear stress, a blood flow-induced frictional force, is essential in the control of endothelial cell (EC) homeostasis. High laminar shear stress (HLSS), as observed in straight parts of arteries, assures a quiescent non-activated endothelium through
Externí odkaz:
https://doaj.org/article/d4e39aa6517b4912b2f208c2ef0119b3
Autor:
Pietro Cacialli, Marie‐Pierre Mailhe, Ingrid Wagner, Doron Merkler, Rachel Golub, Julien Y Bertrand
Publikováno v:
EMBO Journal
EMBO Journal, 2022, pp.e108536. ⟨10.15252/embj.2021108536⟩
EMBO Journal, 2022, pp.e108536. ⟨10.15252/embj.2021108536⟩
International audience; During development, hematopoietic stem cells (HSCs) are produced from the hemogenic endothelium and will expand in a transient hematopoietic niche. Prostaglandin E2 (PGE2) is essential during vertebrate development and HSC spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75ef688b2fca606e8c2b459adf9166f0
https://hal-pasteur.archives-ouvertes.fr/pasteur-03751975
https://hal-pasteur.archives-ouvertes.fr/pasteur-03751975
Autor:
Jessica M. Kraus, Dion Giovannone, Renata Rydzik, Jeremy L. Balsbaugh, Isaac L. Moss, Jennifer L. Schwedler, Julien Y. Bertrand, David Traver, Kurt D. Hankenson, J. Gage Crump, Daniel W. Youngstrom
Publikováno v:
Development
Loss or damage to the mandible caused by trauma, treatment of oral malignancies, and other diseases is treated using bone-grafting techniques that suffer from numerous shortcomings and contraindications. Zebrafish naturally heal large injuries to man
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49a9a0078c7141404e0f9181dc7b1acb
https://europepmc.org/articles/PMC8959151/
https://europepmc.org/articles/PMC8959151/
During embryonic development, very few hematopoietic stem cells (HSCs) are produced from the hemogenic endothelium, that will be expanded in a very specific niche. This fetal HSC niche comprises a complex and dynamic molecular network of interactions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee85247a6fa5bcdee6b3865b08e107d1
https://doi.org/10.1101/2021.04.07.438809
https://doi.org/10.1101/2021.04.07.438809
Autor:
Linnerz T, Julien Y. Bertrand
The family ofdeleted-in-liver-cancer (dlc)genes encodes RhoGTPases and plays pivotal roles in cardiovascular development, but animal models for studying their functions are sparse due to early embryonic lethality. Gain and loss of function ofdlc1andd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::739bb24a7cc3a55cd6d4d16d87777375
https://doi.org/10.1101/2021.02.11.430763
https://doi.org/10.1101/2021.02.11.430763
Autor:
A. Deagostini, V. Braunersreuther, Corentin Pasche, Julien Y. Bertrand, Savvas N. Savvides, Christopher B. Mahony
During early vertebrate development, hematopoietic stem cells (HSCs) are produced from a hemogenic endothelium located in the dorsal aorta, before they migrate to a transient niche where they expand, the fetal liver and the caudal hematopoietic tissu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba378d2c89d3860faca75c098f3e5458
https://doi.org/10.1101/2020.06.23.161406
https://doi.org/10.1101/2020.06.23.161406