Optimization of the treatment with beta-lactam antibiotics in critically ill patients—guidelines from the French Society of Pharmacology and Therapeutics (Société Française de Pharmacologie et Thérapeutique—SFPT) and the French Society of Anaesthesia and Intensive Care Medicine (Société Française d’Anesthésie et Réanimation—SFAR)

Autor: Romain Guilhaumou, Sihem Benaboud, Youssef Bennis, Claire Dahyot-Fizelier, Eric Dailly, Peggy Gandia, Sylvain Goutelle, Sandrine Lefeuvre, Nicolas Mongardon, Claire Roger, Julien Scala-Bertola, Florian Lemaitre, Marc Garnier

Publikováno v: Critical Care, Vol 23, Iss 1, Pp 1-20 (2019)

Abstract Background Beta-lactam antibiotics (βLA) are the most commonly used antibiotics in the intensive care unit (ICU). ICU patients present many pathophysiological features that cause pharmacokinetic (PK) and pharmacodynamic (PD) specificities,

Externí odkaz: https://doaj.org/article/a95e4bbf19074fbd8efce22c8038c53a

Evaluation of KRAS, NRAS and BRAF mutations detection in plasma using an automated system for patients with metastatic colorectal cancer.

Autor: Claire Franczak, Andréa Witz, Karen Geoffroy, Jessica Demange, Marie Rouyer, Marie Husson, Vincent Massard, Céline Gavoille, Aurélien Lambert, Pauline Gilson, Nicolas Gambier, Julien Scala-Bertola, Jean-Louis Merlin, Alexandre Harlé

Publikováno v: PLoS ONE, Vol 15, Iss 1, p e0227294 (2020)

BACKGROUND:Cell-free DNA detection is becoming a surrogate assay for tumor genotyping. Biological fluids often content a very low amount of cell-free tumor DNA and assays able to detect very low allele frequency mutant with a few quantities of DNA ar

Externí odkaz: https://doaj.org/article/2d2a0901bd524592b14f78b4b389cbf9

Assessment of current practice for β-lactam therapeutic drug monitoring in French ICUs in 2021: a nationwide cross-sectional survey

Autor: Perrine Tritscher, Matthieu Delannoy, Nelly Agrinier, Alexandre Charmillon, Nicolas Degand, Jean Dellamonica, Claire Roger, Marc Leone, Julien Scala-Bertola, Emmanuel Novy

Publikováno v: Journal of Antimicrobial Chemotherapy. 77:2650-2657

Background Current guidelines and literature support the use of therapeutic drug monitoring (TDM) to optimize β-lactam treatment in adult ICU patients. Objectives To describe the current practice of β-lactam monitoring in French ICUs. Methods A nat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3be0d9601b3698050ef833b9f68dffc
https://doi.org/10.1093/jac/dkac291

Is therapeutic drug monitoring really helpful for managing piperacillin/tazobactam therapy in critically ill patients?

Autor: Emmanuel Novy, Thomas François, Amandine Luc, Elise Pape, Julien Scala-Bertola

Publikováno v: Intensive care medicine. 48(11)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be4127e5afaf7f243fd95a9e82887f87
https://pubmed.ncbi.nlm.nih.gov/35943572

Paracetamol Misuse and Dental Pain: Results from the French Observational DAntaLor Study

Autor: Claire Collin, Elise Pape, Nicolas Gambier, Julien Scala-Bertola, Emmanuel Puskarczyk, Eric Gérard, Daniel Anastasio, Nadine Petitpain, Lucie Javot, Frédéric Camelot, Céline Clément

Publikováno v: Journal of Oral & Facial Pain and Headache = Journal of Oral and Facial Pain and Headache
Journal of Oral & Facial Pain and Headache = Journal of Oral and Facial Pain and Headache, Quintessence Publishing Co. Inc., 2019, 33 (1), pp.123-129. ⟨10.11607/ofph.1861⟩

Aims To evaluate the risk of hepatotoxicity due to unintentional paracetamol misuse in patients with acute dental pain. Methods A prospective multicenter observational survey was performed in patients consulting, without appointment, the odontology d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fbf38bc8aed15fd494165c3800765de
https://doi.org/10.11607/ofph.1861