Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Julien R. C. Prevost"'
Autor:
Arina Kozlova, Benoît Van den Eynde, Raphaël Frédérick, Simon Klaessens, Léopold Thabault, Caroline Mathieu, Vincent Stroobant, Maxime Liberelle, Luc Pilotte, Julien R. C. Prevost
Publikováno v:
Journal of Medicinal Chemistry, (2021)
Tryptophan 2,3-dioxygenase (TDO2) is a heme-containing enzyme constitutively expressed at high concentrations in the liver and responsible for l-tryptophan (l-Trp) homeostasis. Expression of TDO2 in cancer cells results in the inhibition of immune-me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed66b155772394bcb38fa4f79f3912a7
https://ora.ox.ac.uk/objects/uuid:e29d5aba-ce71-44d4-83fb-2dea9a0345b2
https://ora.ox.ac.uk/objects/uuid:e29d5aba-ce71-44d4-83fb-2dea9a0345b2
Autor:
Benoît Van den Eynde, Julien R. C. Prevost, Arina Kozlova, Luc Pilotte, Maxime Liberelle, Raphaël Frédérick, Simon Klaessens, Caroline Mathieu, Vincent Stroobant, Léopold Thabault
Publikováno v:
Journal of Medicinal Chemistry. 64:13096-13096
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09e0853f7feb319364226d1b157d1196
https://doi.org/10.1021/acs.jmedchem.1c01455
https://doi.org/10.1021/acs.jmedchem.1c01455
Autor:
Esra Yildiz, Eduard Dolusic, Johan Wouters, Bouazza Es Saadi, Sara Modaffari, Julien R. C. Prevost, Lionel Pochet, Didier M. Lambert, Raphaël Frédérick, Arina Kozlova
Publikováno v:
Tetrahedron Letters, Vol. 59, no.49, p. 4315-4319 (2018)
Highly functionalized 5-bromo-2-amino-1,3-thiazoles bearing various substituents could be easily prepared by a rapid and efficient one-pot method, using simple starting materials and mild conditions while avoiding the use of metal catalysts or inconv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b5b87ec49689aaed3179f083facfb6f
https://hdl.handle.net/2078.1/209011
https://hdl.handle.net/2078.1/209011
Autor:
Raphaël Frédérick, Fernand Gbaguidi, Julien R. C. Prevost, Urbain C. Kasséhin, Jacques H. Poupaert, Sédami Medegan Fagla
Publikováno v:
Current Green Chemistry. 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34967694954627a46b29734307857022
https://doi.org/10.2174/2213346104666170704112332
https://doi.org/10.2174/2213346104666170704112332
Autor:
Julien R. C. Prevost, Stefan Munneke, Mattie S. M. Timmer, Gavin F. Painter, Bridget L. Stocker
Publikováno v:
Organic letters. 17(3)
The synthesis of a number of N-glycosyl-N-alkyl-methoxyamine bifunctional linkers is described. The linkers contain an N-methoxyamine functional group for conjugation to carbohydrates and a terminal group, such as an amine, azide, thiol, or carboxyli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51dcae8b9243df7262ab083ae9974d09
https://pubmed.ncbi.nlm.nih.gov/25594534
https://pubmed.ncbi.nlm.nih.gov/25594534
Autor:
Emmanuelle Limanton, Christophe Brigaudeau, Laurence Agouridas, Alain Plenevaux, Raphaël Frédérick, Stéphane Bach, Nicolas Renault, Jose-Manuel Gally, Eric Goffin, Arnaud Caclard, Sebastien Dilly, Arina Kozlova, Jonathan Elie, Nicolas J. P. van Ham, Johan Wouters, Franck Suzenet, Ahmed El Hakmaoui, Floriane Gibault, Mattieu Place, Laurent Meijer, Lionel Pochet, Muriel Pipelier, Pierre Francotte, Jean Pierre Bazureau, Abdelaziz Ejjoummany, Guillemette Huet, Denis Guilloteau, Sandrine Ruchaud, Bernard Pirotte, Tania Tahtouh, Gerard Boyer, Saïd Yous, Pascal Bouyssou, Patricia Melnyk, Aurelien Stutzmann, Pierre Geubelle, Matthieu Corvaisier, Philippe Cotelle, Thomas Dal Maso, Anne Corlu, Samia Aci-Seche, Christelle Ambeu, Mohamed Akssira, Karen Ple, Fabrice Bailly, Janat Akhanovna Mamyrbekova-Bekro, Alan Obled, Rudy Bidault, Sebastien Marx, Yves-Alain Bekro, Guillaume Burgy, Carine Michiels, Sandrine Piguel, Pierre-Louis Brun, Julien Hanson, Anoubile Benie, François Carreaux, Joseph d'Attoma, Emilie Durieu, Fabienne Neulat-Ripoll, Yves Robin, Olivier Mignen, Charlotte Bouckaert, Pascal Bonnet, Marine Schnetterle, Jette Sandholm Kastrup, Jean-Michel Bolla, Solène Guihéneuf, Stephane Bostyn, Chloe Copin, Julien R. C. Prevost, Camille Deliko Dago, Nicolas Arlicot, Wacothon Karime Coulibaly, Thomas Drapier, Anthony Champire, Johnny Vercouille, Luísa V. Lopes, Sandrine Alibert, Gerald Guillaumet, Romain Duroux, Jean-Thomas Heinrich, Frederic Buron, Rémy Le Guével, Fabrice Biot, Laurent Robin, Sylvain Routier, Cerine Michiels, Jean-Marie Pages, Janat Mamyrbekova-Berkro, Eric Valade, Ludovic Paquin
Publikováno v:
Pharmaceuticals
Pharmaceuticals, Vol 9, Iss 4, p 73 (2016)
Pharmaceuticals, Vol 9, Iss 4, p 73 (2016)
The “Journées Franco-Belges de Pharmacochimie” is a recognized annual meeting in organic and medicinal chemistry known for the quality of scientific exchange and conviviality. Young researchers were encouraged to present their work and share ide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::375e8579b51b5c82be3ca9e504cf67af
https://doi.org/10.3390/ph9040073
https://doi.org/10.3390/ph9040073
Autor:
Santiago Agustín Martínez Gache, Tamara Copetti, Quentin Spillier, Raphaël Frédérick, Zohra Benyahia, Julien R. C. Prevost, Chiara Brustenga, Maxime Liberelle, Joris Messens, Pierre Sonveaux, Arina Kozlova, Léopold Thabault, Lucie Brisson
Publikováno v:
Europe PubMed Central
Journal of medicinal chemistry, Vol. 63, no.9, p. 4628-4643 (2020)
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2020, 63 (9), pp.4628-4643. ⟨10.1021/acs.jmedchem.9b01955⟩
Journal of medicinal chemistry, Vol. 63, no.9, p. 4628-4643 (2020)
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2020, 63 (9), pp.4628-4643. ⟨10.1021/acs.jmedchem.9b01955⟩
Lactate dehydrogenases (LDHs) are tetrameric enzymes of major significance in cancer metabolism as well as promising targets for cancer therapy. However, their wide and polar catalytic sites make them a challenging target for orthosteric inhibition.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab9ed9c386778b15fbd0d252a75ed1e5
http://europepmc.org/abstract/med/32250117
http://europepmc.org/abstract/med/32250117