Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Julien Piron"'
Autor:
Fabien C Coyan, Fayal Abderemane-Ali, Mohamed Yassine Amarouch, Julien Piron, Jérôme Mordel, Céline S Nicolas, Marja Steenman, Jean Mérot, Céline Marionneau, Annick Thomas, Robert Brasseur, Isabelle Baró, Gildas Loussouarn
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e93255 (2014)
INTRODUCTION:Phosphatidylinositol-4,5-bisphosphate (PIP2) is a cofactor necessary for the activity of KCNQ1 channels. Some Long QT mutations of KCNQ1, including R243H, R539W and R555C have been shown to decrease KCNQ1 interaction with PIP2. A previou
Externí odkaz:
https://doaj.org/article/2457806624d04ecea1b5be87c18b48d5
Autor:
Julien Piron
L'Ordre vous souhaite la bienvenue à Tenebrium. Que vous soyez Orcs, Trolls, Mages ou Nécromanciens, ici vous pourrez vous bâtir un avenir meilleur loin de toute pollution humaine C'est dans ce pays que Gloria Velner découvre, lors d'une randonn
Autor:
Anne Bourge, Khai Le Quang, Olivier Bignolais, Aziza El Harchi, Julien Piron, Patrice Naud, Anne-Laure Leoni, Flavien Charpentier, François Briec, Sophie Demolombe
Publikováno v:
Journal of Molecular and Cellular Cardiology. 51:713-721
Complete atrioventricular block (CAVB) and related ventricular bradycardia are known to induce ventricular hypertrophy and arrhythmias. Different animal models of CAVB have been established with the most common being the dog model. Related studies we
Autor:
Nicolas Rodriguez, Isabelle Baró, Julien Piron, Flavien Charpentier, Frank S. Choveau, Jean Mérot, Gildas Loussouarn, Mohammed Yassine Amarouch
Publikováno v:
The Journal of Physiology. 588:3471-3483
KCNQ1 osmosensitivity is of physiological and pathophysiological relevance in epithelial and cardiac cells, but the mechanism involved remains elusive. In COS-7 cells expressing the KCNE1–KCNQ1 fusion protein, extracellular hypoosmolarity and hyper
Autor:
Jean Christophe Chevallier, Flavien Charpentier, Howard Motoike, Cecile Terrenoire, Colleen E. Clancy, Sophie Demolombe, Aziza El Harchi, David Mazurais, Gildas Loussouarn, Chloé Bellocq, Gilles Toumaniantz, Denis Escande, Anne Royer, Gilles Lande, Julien Piron, Khai Le Quang
Publikováno v:
Cardiovascular Research. 65:128-137
Objective: The K + channel encoded by the human ether-a`-go-go-related gene (HERG) is crucial for repolarization in the human heart. In order to investigate the impact of HERG current (IKr) on the incidence of cardiac arrhythmias, we generated a tran
Autor:
Céline Marionneau, Gildas Loussouarn, Julien Piron, Mohamed Yassine Amarouch, Robert Brasseur, Marja Steenman, Isabelle Baró, Céline Nicolas, Jean Mérot, Jérôme Mordel, Fabien C. Coyan, Annick Thomas, Fayal Abderemane-Ali
Publikováno v:
PLoS ONE
PLoS ONE, Public Library of Science, 2014, 9 (3), pp.e93255. ⟨10.1371/journal.pone.0093255⟩
PLoS ONE, Vol 9, Iss 3, p e93255 (2014)
PLoS ONE, Public Library of Science, 2014, 9 (3), pp.e93255. ⟨10.1371/journal.pone.0093255⟩
PLoS ONE, Vol 9, Iss 3, p e93255 (2014)
Introduction Phosphatidylinositol-4,5-bisphosphate (PIP2) is a cofactor necessary for the activity of KCNQ1 channels. Some Long QT mutations of KCNQ1, including R243H, R539W and R555C have been shown to decrease KCNQ1 interaction with PIP2. A previou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7beb7951ad43c136f344a077f838a23
https://hal.archives-ouvertes.fr/hal-02363771
https://hal.archives-ouvertes.fr/hal-02363771
Publikováno v:
2010 IEEE International Ultrasonics Symposium.
Contrast agents for ultrasound imaging, composed of tiny gas microbubbles, have become a reality in clinical routine. Recent experimental studies showed that the combination of ultrasound with contrast agent microbubbles increase membrane permeabilit
Autor:
Alain J. Labro, Nicolas Rodriguez, Jérôme Montnach, Isabelle Baró, Mohamed Yassine Amarouch, Julien Piron, Gildas Loussouarn, Flavien Charpentier, Jean Mérot
Publikováno v:
Biophysical Journal
Biophysical Journal, Biophysical Society, 2010, 99 ((4)), pp.1110-8. ⟨10.1016/j.bpj.2010.06.013⟩
Biophysical Journal, 2010, 99 ((4)), pp.1110-8. ⟨10.1016/j.bpj.2010.06.013⟩
Biophysical journal
Biophysical Journal, Biophysical Society, 2010, 99 ((4)), pp.1110-8. ⟨10.1016/j.bpj.2010.06.013⟩
Biophysical Journal, 2010, 99 ((4)), pp.1110-8. ⟨10.1016/j.bpj.2010.06.013⟩
Biophysical journal
International audience; Phosphatidylinositol-4,5-bisphosphate (PIP(2)) is a phospholipid that has been shown to modulate several ion channels, including some voltage-gated channels like Kv11.1 (hERG). From a biophysical perspective, the mechanisms un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29000bc9c439318aac1a99461a65b51b
https://hal.archives-ouvertes.fr/hal-00651490
https://hal.archives-ouvertes.fr/hal-00651490
Publikováno v:
2009 IEEE International Ultrasonics Symposium.
Doxorubicin is an important potent anti-cancer drug and is used for the treatment of various malignancies. Although its effectiveness is proved, its adverse effects are regarded as a problem. Ultrasound and microbubbles are considered as a potent met
Autor:
François Briec, Flavien Charpentier, Bruno Pitard, Julien Piron, Khai Le Quang, Anne-Laure Leoni, Jean-Christophe Amirault, Léa Desigaux, Denis Escande
Publikováno v:
Molecular Therapy
Molecular Therapy, 2008, 16 (12), pp.1937-43. ⟨10.1038/mt.2008.209⟩
Molecular Therapy, Cell Press, 2008, 16 (12), pp.1937-43. ⟨10.1038/mt.2008.209⟩
Molecular Therapy, 2008, 16 (12), pp.1937-43. ⟨10.1038/mt.2008.209⟩
Molecular Therapy, Cell Press, 2008, 16 (12), pp.1937-43. ⟨10.1038/mt.2008.209⟩
International audience; We hypothesized that a nonviral gene delivery of the hyperpolarization-activated HCN2 channel combined with the beta(2)-adrenergic receptor (ADRB2) would generate a functional pacemaker in a mouse model of complete atrioventri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c42e4f155739c46ff8430efd47d44905
https://www.hal.inserm.fr/inserm-00369700
https://www.hal.inserm.fr/inserm-00369700