Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Julien Parra"'
Conformational maps of human 20S proteasomes reveal PA28- and immuno-dependent inter-ring crosstalks
Autor:
Jean Lesne, Marie Locard-Paulet, Julien Parra, Dušan Zivković, Thomas Menneteau, Marie-Pierre Bousquet, Odile Burlet-Schiltz, Julien Marcoux
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Immune cells express immunoproteasomes (i20S), which bind to specialized regulators, contain different catalytic subunits and generate immunogenic peptides. HDX-MS—based assessment of the differences between the conformational dynamics of standard
Externí odkaz:
https://doaj.org/article/ed5d484ebb094784a4e9cc4583e3d0aa
Autor:
Henar Alonso, Julien Parra, Wladimir Malaga, Delphine Payros, Chia-Fang Liu, Céline Berrone, Camille Robert, Etienne Meunier, Odile Burlet-Schiltz, Michel Rivière, Christophe Guilhot
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract Protein O-mannosylation is crucial for the biology of Mycobacterium tuberculosis but the key mannosylated protein(s) involved and its(their) underlying function(s) remain unknown. Here, we demonstrated that the M. tuberculosis mutant (Δpmt)
Externí odkaz:
https://doaj.org/article/f3789c592a2c43ffbed294cffb4cbee9
Autor:
Marie Locard-Paulet, Gautier Prevot, Odile Burlet-Schiltz, Julien Parra, Laura Chiaradia, Gilles Etienne, Julien Marcoux, Maryelle Tropis, Mamadou Daffé, Laurie Thouvenel, Christian Chalut, Emmanuelle Mouton-Barbosa, Christophe Guilhot
Publikováno v:
Thouvenel, L, Prevot, G, Chiaradia, L, Parra, J, Mouton-Barbosa, E, Locard-Paulet, M, Marcoux, J, Tropis, M, Burlet-Schiltz, O, Daffe, M, Guilhot, C, Etienne, G & Chalut, C 2020, ' The final assembly of trehalose polyphleates takes place within the outer layer of the mycobacterial cell envelope ', Journal of Biological Chemistry, vol. 295, no. 32, pp. 11184-11194 . https://doi.org/10.1074/jbc.RA120.013299
J Biol Chem
Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2020, 295 (32), pp.11184-11194. ⟨10.1074/jbc.RA120.013299⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2020
J Biol Chem
Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2020, 295 (32), pp.11184-11194. ⟨10.1074/jbc.RA120.013299⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2020
Trehalose polyphleates (TPP) are high-molecular-weight, surface-exposed glycolipids present in a broad range of nontuberculous mycobacteria. These compounds consist of a trehalose core bearing polyunsaturated fatty acyl substituents (called phleic ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fa199b7e20f17f92b2eb94aaf12461a
https://curis.ku.dk/ws/files/252879123/J._Biol._Chem._2020_Thouvenel_11184_94.pdf
https://curis.ku.dk/ws/files/252879123/J._Biol._Chem._2020_Thouvenel_11184_94.pdf
Autor:
Julien Marcoux, Thomas Menneteau, Jean Lesne, Odile Burlet-Schiltz, Julien Parra, Marie-Pierre Bousquet, Dusan Zivkovic, Marie Locard-Paulet
Publikováno v:
Lesne, J, Locard-Paulet, M, Parra, J, Zivkovic, D, Menneteau, T, Bousquet, M-P, Burlet-Schiltz, O & Marcoux, J 2020, ' Conformational maps of human 20S proteasomes reveal PA28-and immuno-dependent inter-ring crosstalks ', Nature Communications, vol. 11, no. 1, 6140 . https://doi.org/10.1038/s41467-020-19934-z
Nature Communications
Nature Communications, Nature Publishing Group, 2020, ⟨10.1038/s41467-020-19934-z⟩
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications, 2020, ⟨10.1038/s41467-020-19934-z⟩
Nature Communications
Nature Communications, Nature Publishing Group, 2020, ⟨10.1038/s41467-020-19934-z⟩
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications, 2020, ⟨10.1038/s41467-020-19934-z⟩
Hydrogen-Deuterium eXchange coupled to Mass Spectrometry (HDX-MS) is now common practice in structural biology. However, it is most of the time applied to rather small oligomeric complexes. Here, we report on the use of HDX-MS to investigate conforma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80811ed8da17ad82f522814268d3c538
https://curis.ku.dk/ws/files/253732738/s41467_020_19934_z.pdf
https://curis.ku.dk/ws/files/253732738/s41467_020_19934_z.pdf
Autor:
Maryelle Tropis, Alain Milon, Odile Burlet-Schiltz, Julien Parra, Pascal Demange, Guillaume Latgé, Valérie Réat, Julien Marcoux, Mamadou Daffé, Françoise Laval, Marie Renault, Clément Carel
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2017, 114 (16), pp.4231-4236. ⟨10.1073/pnas.1617888114⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2017, 114 (16), pp.4231-4236. ⟨10.1073/pnas.1617888114⟩
The outer membranes (OMs) of members of the Corynebacteriales bacterial order, also called mycomembranes, harbor mycolic acids and unusual outer membrane proteins (OMPs), including those with α-helical structure. The signals that allow precursors of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc6acb477f0bd3be32bde0b9477081c4
https://doi.org/10.1073/pnas.1617888114
https://doi.org/10.1073/pnas.1617888114
Autor:
Clément, Carel, Julien, Marcoux, Valérie, Réat, Julien, Parra, Guillaume, Latgé, Françoise, Laval, Pascal, Demange, Odile, Burlet-Schiltz, Alain, Milon, Mamadou, Daffé, Maryelle G, Tropis, Marie A M, Renault
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 114(16)
Protein secretion is an essential determinant of bacterial physiology and virulence. Members of the Corynebacteriales order have evolved a complex cell envelope containing two membranes, a plasma membrane and an outer membrane, called the mycomembran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ad17a6454c4ef83a39a111c45d08d7f9
https://pubmed.ncbi.nlm.nih.gov/28373551
https://pubmed.ncbi.nlm.nih.gov/28373551
Autor:
Carsten Stoermer, Yury O. Tsybin, Markus Luebeck, Luca Fornelli, Sophie Nallet, Julien Parra, Ralf Hartmer, Florian M. Wurm
Publikováno v:
Analytical Chemistry. 83:8919-8927
Improving qualitative and quantitative characterization of monoclonal antibodies is essential, because of their increasing popularity as therapeutic drug targets. Electron transfer dissociation (ETD)-based top-down mass spectrometry (MS) is the metho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14f831bf6ca39c81d1177ef5dca59b5d
https://doi.org/10.1021/ac201293m
https://doi.org/10.1021/ac201293m
Publikováno v:
Analytical and bioanalytical chemistry. 405(26)
Electron transfer dissociation (ETD)-based top-down mass spectrometry (MS) is the method of choice for in-depth structure characterization of large peptides, small- and medium-sized proteins, and non-covalent protein complexes. Here, we describe the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::780c1785d9b2c347bb8f6b60de95783d
https://pubmed.ncbi.nlm.nih.gov/23934349
https://pubmed.ncbi.nlm.nih.gov/23934349
Autor:
Simone Schmitt, Yury O. Tsybin, Sophie Nallet, Lucia Baldi, Julien Parra, Luca Fornelli, Florian M. Wurm
In this study, a recombinant monoclonal IgG antibody was produced by transient gene expression (TGE) in suspension-adapted HEK-293E cells. The objective of the study was to determine the variation in recombinant IgG yield and glycosylation in ten ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f102e42b86d272d13a21129ebb254520
https://infoscience.epfl.ch/record/176728
https://infoscience.epfl.ch/record/176728