Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Julien Paganini"'
Autor:
Emmanuelle Bernit, Estelle Jean, Bastien Marlot, Laurine Laget, Caroline Izard, Isabelle Dettori, Sophie Beley, Isabelle Gautier, Imane Agouti, Coralie Frassati, Pascal Pedini, Christophe Picard, Julien Paganini, Jacques Chiaroni, Julie Di Cristofaro
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 17, p 13591 (2023)
Red blood cell (RBC) transfusion remains a critical component in caring for the acute and chronic complications of sickle cell disease (SCD). Patient alloimmunisation is the main limitation of transfusion, which can worsen anaemia and lead to delayed
Externí odkaz:
https://doaj.org/article/106c760f96834fb8a810dbdd42754a1c
Autor:
Julien Paganini, Pierre Pontarotti
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Highly polymorphic loci evolved many times over the history of species. These polymorphic loci are involved in three types of functions: kind recognition, self-incompatibility, and the jawed vertebrate adaptive immune system (AIS). In the first part
Externí odkaz:
https://doaj.org/article/9a7ca737b4d4444ea448cb3cc807466f
Autor:
Pierre Pontarotti, Julien Paganini
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 5, p 2665 (2022)
We propose a new hypothesis that explains the maintenance and evolution of MHC polymorphism. It is based on two phenomena: the constitution of the repertoire of naive T lymphocytes and the evolution of the pathogen and its impact on the immune memory
Externí odkaz:
https://doaj.org/article/368d843fd8564a43bea13636a4e28067
Autor:
Julien Paganini, Peter L Nagy, Nicholas Rouse, Philippe Gouret, Jacques Chiaroni, Chistophe Picard, Julie Di Cristofaro
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0242168 (2020)
Many questions can be explored thanks to whole-genome data. The aim of this study was to overcome their main limits, software availability and database accuracy, and estimate the feasibility of red blood cell (RBC) antigen typing from whole-genome se
Externí odkaz:
https://doaj.org/article/e3c78a77683e492097dd339930128c6f
Autor:
François Jordier, Delphine Gras, Maria De Grandis, Xavier-Benoît D'Journo, Pascal-Alexandre Thomas, Pascal Chanez, Christophe Picard, Jacques Chiaroni, Julien Paganini, Julie Di Cristofaro
Publikováno v:
Frontiers in Immunology, Vol 10 (2020)
Little attention is paid to pseudogenes from the highly polymorphic HLA genetic region. The pseudogene HLA-H is defined as a non-functional gene because it is deleted at different frequencies in humans and because it encodes a potentially non-functio
Externí odkaz:
https://doaj.org/article/e13c546cace042f78c6fcebb8f7e3bc4
Autor:
Julien Paganini, Pierre Faux, Sophie Beley, Christophe Picard, Jacques Chiaroni, Julie Di Cristofaro
Publikováno v:
HLA: Immune Response Genetics
HLA: Immune Response Genetics, 2023, ⟨10.1111/tan.15087⟩
HLA: Immune Response Genetics, 2023, ⟨10.1111/tan.15087⟩
International audience; Many specificities single out HLA-F: its structure, expression regulation at cell membrane and function. HLA-F mRNA is detected in the most cell types and the protein is localized in the ER and Golgi apparatus. When expressed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f28516c295bba517e33c367f60442c6b
https://hal.science/hal-04102403
https://hal.science/hal-04102403
Autor:
Lucas Hubert, Julien Paganini, Christophe Picard, Jacques Chiaroni, Laurent Abi-Rached, Pierre Pontarotti, Julie Di Cristofaro
Publikováno v:
Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2021, pp.ji2100358. ⟨10.4049/jimmunol.2100358⟩
Journal of Immunology, 2021, 208 (1), pp.49-53. ⟨10.4049/jimmunol.2100358⟩
Journal of Immunology, 2022, pp.ji2100358. ⟨10.4049/jimmunol.2100358⟩
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2021, pp.ji2100358. ⟨10.4049/jimmunol.2100358⟩
Journal of Immunology, 2021, 208 (1), pp.49-53. ⟨10.4049/jimmunol.2100358⟩
Journal of Immunology, 2022, pp.ji2100358. ⟨10.4049/jimmunol.2100358⟩
The biological relevance of genes initially categorized as “pseudogenes” is slowly emerging, notably in innate immunity. In the HLA region on chromosome 6, HLA-H is one such pseudogene; yet, it is transcribed, and its variation is associated with
Autor:
Camille Ribeyre, Federico Carlini, Céline René, François Jordier, Christophe Picard, Jacques Chiaroni, Laurent Abi-Rached, Philippe Gouret, Grégory Marin, Nicolas Molinari, Pascal Chanez, Julien Paganini, Delphine Gras, Julie Di Cristofaro
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Human leukocyte antigen (HLA)-G, a HLA class Ib molecule, interacts with receptors on lymphocytes such as T cells, B cells, and natural killer cells to influence immune responses. Unlike classical HLA molecules, HLA-G expression is not found on all s
Externí odkaz:
https://doaj.org/article/07099ca8a4c74ed18aee3939b899d645
Autor:
Laurent Abi-Rached, Philippe Gouret, Jung-Hua Yeh, Julie Di Cristofaro, Pierre Pontarotti, Christophe Picard, Julien Paganini
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0206512 (2018)
Defining worldwide human genetic variation is a critical step to reveal how genome plasticity contributes to disease. Yet, there is currently no metric to assess the representativeness and completeness of current and widely used data on genetic varia
Externí odkaz:
https://doaj.org/article/a59e055825634da0b1b00ae9b5219f3e
Publikováno v:
Trends in Genetics
Trends in Genetics, Elsevier, 2021, 37 (5), pp.414-420. ⟨10.1016/j.tig.2020.10.001⟩
Trends in Genetics, 2021, 37 (5), pp.414-420. ⟨10.1016/j.tig.2020.10.001⟩
Trends in Genetics, Elsevier, 2021, 37 (5), pp.414-420. ⟨10.1016/j.tig.2020.10.001⟩
Trends in Genetics, 2021, 37 (5), pp.414-420. ⟨10.1016/j.tig.2020.10.001⟩
The relationship between human genetic variation and disease has not been fully elucidated. According to the present view on infectious diseases pathogen resistance is linked to human leukocyte antigen (HLA) class I/II variants and their individual c