Výsledky vyhledávání - "Julien Nadjar"

Akademický článek

Analysis of virion-incorporated host proteins required for herpes simplex virus type 1 infection through a RNA interference screen.

Autor: Camille Stegen, Yordanka Yakova, Daniel Henaff, Julien Nadjar, Johanne Duron, Roger Lippé

Publikováno v: PLoS ONE, Vol 8, Iss 1, p e53276 (2013)

Viruses are strictly dependent on cells to propagate and many incorporate host proteins in their viral particles, but the significance of this incorporation is poorly understood. Recently, we performed the first comprehensive characterization of the

Externí odkaz: https://doaj.org/article/2caaaf81eb2749ca802e56cc9415e677

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Akademický článek

Multi-level interactions between the nuclear receptor TRα1 and the WNT effectors β-catenin/Tcf4 in the intestinal epithelium.

Autor: Maria Sirakov, Seham Skah, Imtiaz Nisar Lone, Julien Nadjar, Dimitar Angelov, Michelina Plateroti

Publikováno v: PLoS ONE, Vol 7, Iss 4, p e34162 (2012)

Intestinal homeostasis results from complex cross-regulation of signaling pathways; their alteration induces intestinal tumorigenesis. Previously, we found that the thyroid hormone nuclear receptor TRα1 activates and synergizes with the WNT pathway,

Externí odkaz: https://doaj.org/article/0c133a07de4848de9278e11ecfed1173

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The thyroid hormone nuclear receptor TRα1 controls the Notch signaling pathway and cell fate in murine intestine

Autor: Dimitar Angelov, Michelina Plateroti, Imtiaz Nisar Lone, Carla Frau, Amina Boussouar, Julien Nadjar, Maria Sirakov, Elsa Kress

Publikováno v: Development. 142:2764-2774

Thyroid hormones control various aspects of gut development and homeostasis. The best-known example is in gastrointestinal tract remodeling during amphibian metamorphosis. It is well documented that these hormones act via the TR nuclear receptors, wh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54259b8d4832deffdfc2df3dd3f37994
https://doi.org/10.1242/dev.121962

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The secreted Frizzled-Related Protein 2 modulates cell fate and the Wnt pathway in the murine intestinal epithelium

Autor: Seham Skah, Michelina Plateroti, Julien Nadjar, Maria Sirakov

Publikováno v: Experimental Cell Research. 330:56-65

The secreted Frizzled-Related Proteins (sFRPs) are generally considered antagonistic to Wnt signaling. However, several studies have described their synergy and/or activation of this pathway. Our own data indicated that in the intestinal epithelium,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64c9176815ac2888ad2d5d043255f86e
https://doi.org/10.1016/j.yexcr.2014.10.014

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Brief report: Musashi1-eGFP mice, a new tool for differential isolation of the intestinal stem cell populations

Autor: Francesca Maria Cambuli, Michelina Plateroti, Amélie Rezza, Julien Nadjar

Publikováno v: Stem Cells. 31:2273-2278

The intestinal epithelium self-renews rapidly and continuously throughout life, due to the presence of crypt stem cells. Two pools of these cells have been identified in the small intestine, which differ in position (“+4” or the bottom of the cry

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::590ba8ef1e72a34706e45436c491d1f1
https://doi.org/10.1002/stem.1428

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Thyroid hormone's action on progenitor/stem cell biology: New challenge for a classic hormone?

Autor: Seham Skah, Julien Nadjar, Maria Sirakov, Michelina Plateroti

Publikováno v: Biochimica et Biophysica Acta (BBA) - General Subjects. 1830:3917-3927

Background Thyroid hormones are involved in developmental and homeostatic processes in several tissues. Their action results in different outcomes depending on the developmental stage, tissue and/or cellular context. Interestingly, their pleiotropic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40cb7540159356dd0ab697b2b81cf25e
https://doi.org/10.1016/j.bbagen.2012.07.014

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Thyroid hormones and their nuclear receptors: new players in intestinal epithelium stem cell biology?

Autor: Michelina Plateroti, Julien Nadjar, Elsa Kress, Maria Sirakov

Publikováno v: Cellular and molecular life sciences : CMLS. 71(15)

Thyroid hormones participate in the development and homeostasis of several organs and tissues. It is well documented that they act via nuclear receptors, the TRs, which are transcription factors whose function is modulated by the hormone T3. Importan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe1238d0ae3c677b52940464c2eddd8b
https://pubmed.ncbi.nlm.nih.gov/24604390

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Multi-Level Interactions between the Nuclear Receptor TRα1 and the WNT Effectors β-Catenin/Tcf4 in the Intestinal Epithelium

Autor: Michelina Plateroti, Seham Skah, Imtiaz Nisar Lone, Maria Sirakov, Dimitar Angelov, Julien Nadjar

Publikováno v: PLoS ONE
PLoS ONE, 2012, 7 (4), pp.e34162. ⟨10.1371/journal.pone.0034162⟩
Plos One 4 (7), . (2012)
PLoS ONE, Public Library of Science, 2012, 7 (4), pp.e34162. ⟨10.1371/journal.pone.0034162⟩
PLoS ONE, Vol 7, Iss 4, p e34162 (2012)
PloS one, 7 (4

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4c8561099affbf52b3aea2b13bb847c
http://europepmc.org/articles/PMC3317923

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The overexpression of the putative gut stem cell marker Musashi-1 induces tumorigenesis through Wnt and Notch activation

Autor: Colette Roche, Amélie Rezza, Seham Skah, Jacques Samarut, Julien Nadjar, Michelina Plateroti

Publikováno v: Journal of Cell Science
Journal of Cell Science, 2010, 123 (19), pp.3256-3265. ⟨10.1242/jcs.065284⟩
Journal of Cell Science, Company of Biologists, 2010, 123 (19), pp.3256-3265. ⟨10.1242/jcs.065284⟩

International audience; The RNA-binding protein Musashi-1 (Msi1) has been proposed as a marker of intestinal epithelial stem cells. These cells are responsible for the continuous renewal of the intestinal epithelium. Although the function of Msi1 has

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf9ca703135fef44515f52051f09ea95
https://doi.org/10.1242/jcs.065284

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Autor: Elsa Kress, Julien Nadjar, Amélie Rezza, Michelina Plateroti, Jacques Samarut

Publikováno v: Journal of Biological Chemistry 2 (284), 1234-1241. (2009)
Journal of Biological Chemistry
Journal of Biological Chemistry, 2009, 284 (2), pp.1234-1241. ⟨10.1074/jbc.M806548200⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2009, 284 (2), pp.1234-1241. ⟨10.1074/jbc.M806548200⟩

International audience; The thyroid hormone receptor TR alpha 1 regulates intestinal development and homeostasis by controlling epithelial proliferation in the crypts. This involves positive control of the Wnt/beta-catenin pathway. To further investi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dc48fc80d9eb44e191c36ea93bba9e2
http://prodinra.inra.fr/record/32327

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