Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Julien Mortier"'
Autor:
Daniel Berdejo, Julien Mortier, Alexander Cambré, Malgorzata Sobota, Ronald Van Eyken, Tom Dongmin Kim, Kristof Vanoirbeek, Diego García Gonzalo, Rafael Pagán, Médéric Diard, Abram Aertsen
Publikováno v:
mBio, Vol 15, Iss 3 (2024)
ABSTRACT Understanding the evolutionary dynamics of foodborne pathogens throughout our food production chain is of utmost importance. In this study, we reveal that Salmonella Typhimurium can readily and reproducibly acquire vastly increased heat shoc
Externí odkaz:
https://doaj.org/article/6dc8d48a63b0436abf8c60e01d35f604
Publikováno v:
PLoS Genetics, Vol 19, Iss 11, p e1010882 (2023)
Upon nutrient depletion, bacteria stop proliferating and undergo physiological and morphological changes to ensure their survival. Yet, how these processes are coordinated in response to distinct starvation conditions is poorly understood. Here we co
Externí odkaz:
https://doaj.org/article/5243eb64da9045aea628316a60e11e3e
Publikováno v:
Microorganisms, Vol 11, Iss 9, p 2365 (2023)
In order to improve our general understanding of protein aggregate (PA) management and impact in bacteria, different model systems and processes need to be investigated. As such, we developed an inducible synthetic PA model system to investigate PA d
Externí odkaz:
https://doaj.org/article/bb7e1b3c117d45cba6d38d4956e14c11
Heterogeneity and Evolutionary Tunability of Escherichia coli Resistance against Extreme Acid Stress
Autor:
Stefanie Van Riet, Wubishet Tadesse, Julien Mortier, Susan Schlegel, Kenneth Simoens, Kristel Bernaerts, Alma Dal Co, Abram Aertsen
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 6 (2022)
ABSTRACT Since acidic environments often serve as an important line of defense against bacterial pathogens, it is important to fully understand how the latter manage to mount and evolve acid resistance mechanisms. Escherichia coli, a species harborin
Externí odkaz:
https://doaj.org/article/24881b81960a46a6a1a1fea0cdbc8d91
Autor:
Malgorzata Sobota, Pilar Natalia Rodilla Ramirez, Alexander Cambré, Andrea Rocker, Julien Mortier, Théo Gervais, Tiphaine Haas, Delphine Cornillet, Dany Chauvin, Isabelle Hug, Thomas Julou, Abram Aertsen, Médéric Diard
Publikováno v:
PLoS Biology, Vol 20, Iss 4, p e3001608 (2022)
Virulence gene expression can represent a substantial fitness cost to pathogenic bacteria. In the model entero-pathogen Salmonella Typhimurium (S.Tm), such cost favors emergence of attenuated variants during infections that harbor mutations in transc
Externí odkaz:
https://doaj.org/article/c1736e33abf2409ba70b98328de2c0af
Autor:
Julien Mortier, Stefanie Van Riet, Diana Senovilla Herrero, Kristof Vanoirbeek, Abram Aertsen
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 1 (2022)
ABSTRACT Elucidating phenotypic heterogeneity in clonal bacterial populations is important for both the fundamental understanding of bacterial behavior and the synthetic engineering of bacteria in biotechnology. In this study, we present and validate
Externí odkaz:
https://doaj.org/article/3ed4a122817947ea960ff00f281667af
Autor:
Julien Mortier, Elisa Gayán, Ronald Van Eyken, Oscar Enrique Torres Montaguth, Ladan Khodaparast, Laleh Khodaparast, Bert Houben, Sebastien Carpentier, Frederic Rousseau, Joost Schymkowitz, Abram Aertsen
Publikováno v:
mBio, Vol 12, Iss 5 (2021)
Externí odkaz:
https://doaj.org/article/6181e41b179949fd972c8e6a0294d192
Autor:
Julien Mortier, Elisa Gayán, Ronald Van Eyken, Oscar Enrique Torres Montaguth, Ladan Khodaparast, Laleh Khodaparast, Bert Houben, Sebastien Carpentier, Frederic Rousseau, Joost Schymkowitz, Abram Aertsen
Publikováno v:
mBio, Vol 12, Iss 4 (2021)
ABSTRACT Despite our extensive knowledge of the genetic regulation of heat shock proteins (HSPs), the evolutionary routes that allow bacteria to adaptively tune their HSP levels and corresponding proteostatic robustness have been explored less. In th
Externí odkaz:
https://doaj.org/article/623a01e2ab7646c0bffe2fbedf477587
Publikováno v:
PLoS Biology, Vol 16, Iss 8, p e2003853 (2018)
Protein misfolding and aggregation are typically perceived as inevitable and detrimental processes tied to a stress- or age-associated decline in cellular proteostasis. A careful reassessment of this paradigm in the E. coli model bacterium revealed t
Externí odkaz:
https://doaj.org/article/ed553c5cdfe140749c1b9da819fca870
Autor:
Ronald Van Eyken, Abram Aertsen, Laleh Khodaparast, Sebastien Carpentier, Elisa Gayán, Joost Schymkowitz, Oscar Enrique Torres Montaguth, Bert Houben, Frederic Rousseau, Julien Mortier, Ladan Khodaparast
Publikováno v:
mBio
mBio, Vol 12, Iss 5 (2021)
mBio, Vol 12, Iss 5 (2021)
Despite our extensive knowledge of the genetic regulation of heat shock proteins (HSPs), the evolutionary routes that allow bacteria to adaptively tune their HSP levels and corresponding proteostatic robustness have been explored less. In this report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58f501ac360e75aa17724c3b34d81fee
http://europepmc.org/articles/PMC8546574
http://europepmc.org/articles/PMC8546574