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pro vyhledávání: '"Julien Morival"'
Autor:
Annie Trinh, Yi Huang, Hanjuan Shao, Aparna Ram, Julien Morival, Jonathan Wang, Eun Ji Chung, Timothy L. Downing
Publikováno v:
APL Bioengineering, Vol 7, Iss 2, Pp 026111-026111-17 (2023)
DNA methylation aberrancies are found in autosomal dominant polycystic kidney disease (ADPKD), which suggests the methylome to be a promising therapeutic target. However, the impact of combining DNA methylation inhibitors (DNMTi) and ADPKD drugs in t
Externí odkaz:
https://doaj.org/article/63321ba8efed412788bcee564dc06a85
Autor:
Luis Busto-Moner, Julien Morival, Honglei Ren, Arjang Fahim, Zachary Reitz, Timothy L Downing, Elizabeth L Read
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 4, p e1007195 (2020)
DNA methylation is a heritable epigenetic modification that plays an essential role in mammalian development. Genomic methylation patterns are dynamically maintained, with DNA methyltransferases mediating inheritance of methyl marks onto nascent DNA
Externí odkaz:
https://doaj.org/article/3aeeb43d2c62484aa88d0013ba4b891c