Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Julien Lemaître"'
Autor:
Pauline Maisonnasse, Yoann Aldon, Aurélien Marc, Romain Marlin, Nathalie Dereuddre-Bosquet, Natalia A. Kuzmina, Alec W. Freyn, Jonne L. Snitselaar, Antonio Gonçalves, Tom G. Caniels, Judith A. Burger, Meliawati Poniman, Ilja Bontjer, Virginie Chesnais, Ségolène Diry, Anton Iershov, Adam J. Ronk, Sonia Jangra, Raveen Rathnasinghe, Philip J. M. Brouwer, Tom P. L. Bijl, Jelle van Schooten, Mitch Brinkkemper, Hejun Liu, Meng Yuan, Chad E. Mire, Mariëlle J. van Breemen, Vanessa Contreras, Thibaut Naninck, Julien Lemaître, Nidhal Kahlaoui, Francis Relouzat, Catherine Chapon, Raphaël Ho Tsong Fang, Charlene McDanal, Mary Osei-Twum, Natalie St-Amant, Luc Gagnon, David C. Montefiori, Ian A. Wilson, Eric Ginoux, Godelieve J. de Bree, Adolfo García-Sastre, Michael Schotsaert, Lynda Coughlan, Alexander Bukreyev, Sylvie van der Werf, Jérémie Guedj, Rogier W. Sanders, Marit J. van Gils, Roger Le Grand
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Monoclonal antibodies show great promise in treating Covid-19 patients. Here, Maisonnasse, Aldon and colleagues report pre-clinical results for COVA1-18 and demonstrate that it reduces viral infectivity in three animal models with over 95% efficacy i
Externí odkaz:
https://doaj.org/article/cb63fd675fbc4192b0ac21fa54904b08
Autor:
Cindy Adapen, Louis Réot, Natalia Nunez, Claude Cannou, Romain Marlin, Julien Lemaître, Léo d’Agata, Emmanuel Gilson, Eric Ginoux, Roger Le Grand, Marie-Thérèse Nugeyre, Elisabeth Menu
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundThe female reproductive tract (FRT) mucosa is the first line of defense against sexually transmitted infection (STI). FRT environmental factors, including immune-cell composition and the vaginal microbiota, interact with each other to modul
Externí odkaz:
https://doaj.org/article/369f4a48cda9426a82d646994eb65b87
Autor:
Mathilde Galhaut, Urban Lundberg, Romain Marlin, Robert Schlegl, Stefan Seidel, Ursula Bartuschka, Jürgen Heindl-Wruss, Francis Relouzat, Sébastien Langlois, Nathalie Dereuddre-Bosquet, Julie Morin, Maxence Galpin-Lebreau, Anne-Sophie Gallouët, Wesley Gros, Thibaut Naninck, Quentin Pascal, Catherine Chapon, Karine Mouchain, Guillaume Fichet, Julien Lemaitre, Mariangela Cavarelli, Vanessa Contreras, Nicolas Legrand, Andreas Meinke, Roger Le Grand
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-11 (2024)
Abstract Background The fight against COVID-19 requires mass vaccination strategies, and vaccines inducing durable cross-protective responses are still needed. Inactivated vaccines have proven lasting efficacy against many pathogens and good safety r
Externí odkaz:
https://doaj.org/article/b20cf0b0a10841d78b8331ab24c32b42
Autor:
Caroline Passaes, Delphine Desjardins, Anaïs Chapel, Valérie Monceaux, Julien Lemaitre, Adeline Mélard, Federico Perdomo-Celis, Cyril Planchais, Maël Gourvès, Nastasia Dimant, Annie David, Nathalie Dereuddre-Bosquet, Aurélie Barrail-Tran, Hélène Gouget, Céline Guillaume, Francis Relouzat, Olivier Lambotte, Jérémie Guedj, Michaela Müller-Trutwin, Hugo Mouquet, Christine Rouzioux, Véronique Avettand-Fenoël, Roger Le Grand, Asier Sáez-Cirión
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract HIV remission can be achieved in some people, called post-treatment HIV controllers, after antiretroviral treatment discontinuation. Treatment initiation close to the time of infection was suggested to favor post-treatment control, but the c
Externí odkaz:
https://doaj.org/article/661b86229b42429d8450453e606a9ab0
Autor:
Romain Marlin, Delphine Desjardins, Vanessa Contreras, Guillaume Lingas, Caroline Solas, Pierre Roques, Thibaut Naninck, Quentin Pascal, Sylvie Behillil, Pauline Maisonnasse, Julien Lemaitre, Nidhal Kahlaoui, Benoit Delache, Andrés Pizzorno, Antoine Nougairede, Camille Ludot, Olivier Terrier, Nathalie Dereuddre-Bosquet, Francis Relouzat, Catherine Chapon, Raphael Ho Tsong Fang, Sylvie van der Werf, Manuel Rosa Calatrava, Denis Malvy, Xavier de Lamballerie, Jeremie Guedj, Roger Le Grand
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Repurposed antiviral drugs present as a valuable resource in the defence during outbreaks, with rigorous evaluation in large animal models keys for translation to clinical implementation. Here, the authors explore the antiviral activity of favipiravi
Externí odkaz:
https://doaj.org/article/cee3e8b3e2194e7993477900e8552973
Autor:
Anaëlle Olivo, Romain Marlin, Thierry Lazure, Pauline Maisonnasse, Laetitia Bossevot, Christelliah Mouanga, Julien Lemaitre, Guillaume Pourcher, Stéphane Benoist, Roger Le Grand, Olivier Lambotte, Nathalie Dereuddre-Bosquet, Christine Bourgeois
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-10 (2022)
Subcutaneous fat tissue expresses higher angiotensin-converting-enzyme 2 mRNA than visceral fat tissue and is selectively infected by SARS-Cov-2, while both fat tissues show drastic reduction in CD69 expression in T cells.
Externí odkaz:
https://doaj.org/article/9400b81c787348eb97367228321efdf7
Autor:
Antoine Rousseau, Oscar Haigh, Roger Legrand, Jean-Louis Palgen, Julien Lemaitre, Claire Deback, Noémie Oziol, Patrick Lomonte, Marc Labetoulle
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Primary infection with herpes simplex type 1 (HSV-1) occurring around the mouth and nose switches rapidly to lifelong latent infection in sensitive trigeminal ganglia (TG) neurons. Sporadic reactivation of these latent reservoirs later in li
Externí odkaz:
https://doaj.org/article/759feb6d36e04fe28cf79e556fcd4273
Autor:
Romain Marlin, Veronique Godot, Sylvain Cardinaud, Mathilde Galhaut, Severin Coleon, Sandra Zurawski, Nathalie Dereuddre-Bosquet, Mariangela Cavarelli, Anne-Sophie Gallouët, Pauline Maisonnasse, Léa Dupaty, Craig Fenwick, Thibaut Naninck, Julien Lemaitre, Mario Gomez-Pacheco, Nidhal Kahlaoui, Vanessa Contreras, Francis Relouzat, Raphaël Ho Tsong Fang, Zhiqing Wang, Jerome Ellis, Catherine Chapon, Mireille Centlivre, Aurelie Wiedemann, Christine Lacabaratz, Mathieu Surenaud, Inga Szurgot, Peter Liljeström, Delphine Planas, Timothée Bruel, Olivier Schwartz, Sylvie van der Werf, Giuseppe Pantaleo, Mélanie Prague, Rodolphe Thiébaut, Gerard Zurawski, Yves Lévy, Roger Le Grand
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
In this study, Marlin et al. provide insights into the potential use of subunit vaccines that induce a high level of protection against SARS-CoV-2 in animal models.
Externí odkaz:
https://doaj.org/article/70f82fe99a894f91b058c7b831c415e2
Autor:
Thibaut Naninck, Nidhal Kahlaoui, Julien Lemaitre, Pauline Maisonnasse, Antoine De Mori, Quentin Pascal, Vanessa Contreras, Romain Marlin, Francis Relouzat, Benoît Delache, Cécile Hérate, Yoann Aldon, Marit van Gils, Nerea Zabaleta, Raphaël Ho Tsong Fang, Nathalie Bosquet, Rogier W. Sanders, Luk H. Vandenberghe, Catherine Chapon, Roger Le Grand
Publikováno v:
iScience, Vol 25, Iss 4, Pp 104101- (2022)
Summary: Non-human primates (NHPs) are particularly relevant as preclinical models for SARS-CoV-2 infection and nuclear imaging may represent a valuable tool for monitoring infection in this species. We investigated the benefit of computed X-ray tomo
Externí odkaz:
https://doaj.org/article/f12f03d30c0a4e47bd9abf390fbc8fec
Autor:
Julien Lemaitre, Delphine Desjardins, Anne-Sophie Gallouët, Mario Gomez-Pacheco, Christine Bourgeois, Benoit Favier, Asier Sáez-Cirión, Roger Le Grand, Olivier Lambotte
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
In spite of the efficacy of combinational antiretroviral treatment (cART), HIV-1 persists in the host and infection is associated with chronic inflammation, leading to an increased risk of comorbidities, such as cardiovascular diseases, neurocognitiv
Externí odkaz:
https://doaj.org/article/1fb27faeff6540bb94cdcdc100878e45