Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Julien Grynblat"'
Autor:
Alban Todesco, Julien Grynblat, Kouamé Kan Firmin Akoumia, Damien Bonnet, Pedro Mendes‐Ferreira, Stéphane Morisset, Denis Chemla, Marilyne Levy, Mathilde Méot, Sophie‐Guiti Malekzadeh‐Milani, Birger Tielemans, Benoit Decante, Carine Vastel‐Amzallag, Paul Habert, Maria‐Rosa Ghigna, Marc Humbert, David Montani, David Boulate, Frédéric Perros
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 14 (2024)
Background The primary genetic risk factor for heritable pulmonary arterial hypertension is the presence of monoallelic mutations in the BMPR2 gene. The incomplete penetrance of BMPR2 mutations implies that additional triggers are necessary for pulmo
Externí odkaz:
https://doaj.org/article/4520f0f27dce4d70ad92d5eac4842764
Autor:
Sharon Mumby, Frederic Perros, Julien Grynblat, Gregoire Manaud, Alberto Papi, Paolo Casolari, Gaetano Caramori, Marc Humbert, S. John Wort, Ian M. Adcock
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-16 (2023)
Abstract Background Pulmonary arterial hypertension (PAH) encompasses a group of diseases characterized by raised pulmonary vascular resistance, resulting from vascular remodelling and inflammation. Bromodomain and extra-terminal (BET) proteins are r
Externí odkaz:
https://doaj.org/article/c329a62700014b68975999176cca51b6
Autor:
David Montani, Fabrice Antigny, Etienne-Marie Jutant, Marie-Camille Chaumais, Hélène Le Ribeuz, Julien Grynblat, Charles Khouri, Marc Humbert
Publikováno v:
ERJ Open Research, Vol 9, Iss 6 (2023)
The ATP-sensitive potassium channels and their regulatory subunits, sulfonylurea receptor 1 (SUR1/Kir6.2) and SUR2/Kir6.1, contribute to the pathophysiology of pulmonary hypertension (PH). Loss-of-function pathogenic variants in the ABCC8 gene, which
Externí odkaz:
https://doaj.org/article/0b1daad67e1742e7ae47fb4de467b6e4
Autor:
Julien Grynblat, Sophie‐Guiti Malekzadeh‐Milani, Mathilde Meot, Frédéric Perros, Isabelle Szezepanski, Stéphane Morisset, Caroline Ovaert, Caroline Bonnet, Pascale Maragnes, Julien Ranchoup, Marc Humbert, I. David Montani, Marilyne Levy, Damien Bonnet
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 7 (2023)
Background Right heart catheterization (RHC) is a high‐risk procedure in children with pulmonary arterial hypertension without clear guidelines for the indications and targets of invasive reassessment. Our objectives are to define the aims of repea
Externí odkaz:
https://doaj.org/article/9fb93ed500e744ac959328a11c868112
Autor:
Eamon P. Mulvaney, Fabiana Renzo, Rui Adão, Emilie Dupre, Lucia Bialesova, Viviana Salvatore, Helen M. Reid, Glória Conceição, Julien Grynblat, Aida Llucià-Valldeperas, Jean-Baptiste Michel, Carmen Brás-Silva, Charles E. Laurent, Luke S. Howard, David Montani, Marc Humbert, Anton Vonk Noordegraaf, Frédéric Perros, Pedro Mendes-Ferreira, B. Therese Kinsella
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundPulmonary arterial hypertension (PAH) is a progressive disease characterized by increased pulmonary artery pressure leading to right ventricular (RV) failure. While current PAH therapies improve patient outlook, they show limited benefit in
Externí odkaz:
https://doaj.org/article/61ac0e73143f434fb6aee88b5fe3d60f
Autor:
Feriel, Benchenouf, Alessandra, Cuomo, Deborah, Gorth J., Corinne, Normand, Raphaël, Thuillet, Mina, Ottaviani, Ali, Akamkam, Jean-Baptiste, Menager, Guillaume, Fadel, Julien, Grynblat, Maria-Rosa, Ghigna, Elie, Fadel, Laurent, Savale, Olaf, Mercier, Ly, Tu, Marc, Humbert, Christophe, Guignabert
Publikováno v:
Scientific Reports; 11/16/2024, Vol. 14 Issue 1, p1-11, 11p