Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Julien Funk"'
Autor:
Rachel Sealfon, Laura Mariani, Carmen Avila-Casado, Viji Nair, Rajasree Menon, Julien Funk, Aaron Wong, Gabriel Lerner, Norifumi Hayashi, Olga Troyanskaya, Matthias Kretzler, Laurence H. Beck
Publikováno v:
J Am Soc Nephrol
BACKGROUND: Molecular characterization of nephropathies may facilitate pathophysiologic insight, development of targeted therapeutics, and transcriptome-based disease classification. Although membranous nephropathy (MN) is a common cause of adult-ons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8580b3230fb9cce7d614d3eb339add8a
https://pubmed.ncbi.nlm.nih.gov/35477557
https://pubmed.ncbi.nlm.nih.gov/35477557
Autor:
Chandra L. Theesfeld, Olga G. Troyanskaya, Vessela N. Kristensen, Dmitriy Gorenshteyn, Amy C. Durham, James A. Cahill, John D. Storey, Julien Funk, Kiley Graim, Rumela Chakrabarti, David G. Robinson, Michael H. Goldschmidt, Karin U. Sorenmo, Nicholas J. Carriero
Publikováno v:
Genome Res
Understanding the changes in diverse molecular pathways underlying the development of breast tumors is critical for improving diagnosis, treatment, and drug development. Here, we used RNA-profiling of canine mammary tumors (CMTs) coupled with a robus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f93ca6f5fb7858678a3a5c8a7c5d0571
https://pubmed.ncbi.nlm.nih.gov/33361113
https://pubmed.ncbi.nlm.nih.gov/33361113
Autor:
Chandra L. Theesfeld, Nicholas Carriero, Olga G. Troyanskaya, Amy C. Durham, Kiley Graim, Vessela N. Kristensen, John D. Storey, Dmitriy Gorenshteyn, Julien Funk, David G. Robinson, Karin U. Sorenmo, Michael H. Goldschmidt, Rumela Chakrabarti, James A. Cahill
Publikováno v:
Cancer Research. 80:2504-2504
Malignancy in cancer is a consequence of the progressive accumulation of mutations in a tumor, with profound implications for drug selection and treatment. However, in human studies, inter-patient variability obscures molecular signatures of tumor pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b14aeed78de6d83c7636b447ffaf0523
https://doi.org/10.1158/1538-7445.am2020-2504
https://doi.org/10.1158/1538-7445.am2020-2504
Autor:
John J. Fak, Robert B. Darnell, Yuan Yuan, Christopher Y. Park, Claudia Scheckel, Chandra L. Theesfeld, Yoko Tajima, Kevin Yao, Julien Funk, Alan Packer, Aaron K. Wong, Jian Zhou, Olga G. Troyanskaya
Publikováno v:
Nature genetics. 51(6)
We address the challenge of detecting the contribution of noncoding mutations to disease with a deep-learning-based framework that predicts the specific regulatory effects and the deleterious impact of genetic variants. Applying this framework to 1,7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::256479268f29d9eeb8c40615ae2c78d7
https://pubmed.ncbi.nlm.nih.gov/31133750
https://pubmed.ncbi.nlm.nih.gov/31133750