Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Julien Ferent"'
Publikováno v:
Cells, Vol 12, Iss 2, p 225 (2023)
A morphogen is a signaling molecule that induces specific cellular responses depending on its local concentration. The concept of morphogenic gradients has been a central paradigm of developmental biology for decades. Sonic Hedgehog (Shh) is one of t
Externí odkaz:
https://doaj.org/article/b38e7225ac564bfa911c46d3624996eb
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
During the development of the cortex, newly generated neurons migrate long-distances in the expanding tissue to reach their final positions. Pyramidal neurons are produced from dorsal progenitors, e.g., radial glia (RGs) in the ventricular zone, and
Externí odkaz:
https://doaj.org/article/e2f05e87ec9c407caa49c37a5f63d0f6
Autor:
Julien Ferent, Sandii Constable, Eduardo D. Gigante, Patricia T. Yam, Laura E. Mariani, Emilie Legué, Karel F. Liem, Jr., Tamara Caspary, Frédéric Charron
Publikováno v:
Cell Reports, Vol 29, Iss 11, Pp 3356-3366.e3 (2019)
Summary: The small GTPase Arl13b is enriched in primary cilia and regulates Sonic hedgehog (Shh) signaling. During neural development, Shh controls patterning and proliferation through a canonical, transcription-dependent pathway that requires the pr
Externí odkaz:
https://doaj.org/article/9a2d657e0e474c2d9ac61327fe688811
Autor:
Julien Ferent, Loïc Cochard, Hélène Faure, Maurizio Taddei, Heidi Hahn, Martial Ruat, Elisabeth Traiffort
Publikováno v:
Stem Cell Reports, Vol 3, Iss 2, Pp 312-323 (2014)
In the adult brain, self-renewal is essential for the persistence of neural stem cells (NSCs) throughout life, but its regulation is still poorly understood. One NSC can give birth to two NSCs or one NSC and one transient progenitor. A correct balanc
Externí odkaz:
https://doaj.org/article/b071b95047814f7187ff97364fd1f161
Publikováno v:
Journal of Developmental Biology, Vol 4, Iss 3, p 28 (2016)
The Hedgehog morphogen aroused an enormous interest since it was characterized as an essential signal for ventral patterning of the spinal cord two decades ago. The pathway is notably implicated in the initial appearance of the progenitors of oligode
Externí odkaz:
https://doaj.org/article/f896b4cf1d4e427499a6bc7ddaad829d
Autor:
Louise Thiry, Chloé Lemaire, Ali Rastqar, Maxime Lemieux, Jimmy Peng, Julien Ferent, Marie Roussel, Eric Beaumont, James P. Fawcett, Robert M. Brownstone, Frédéric Charron, Frédéric Bretzner
Publikováno v:
eneuro. 9:ENEURO.0216-18.2021
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a74739d27c02ae20220b4dac126fd08c
https://doi.org/10.1523/eneuro.0216-18.2021
https://doi.org/10.1523/eneuro.0216-18.2021
Autor:
Frédéric Charron, Elisabeth Traiffort, Amina Zahaf, Mary Zakaria, Olivier Pascual, Abdelmoumen Kassoussi, Ines Hristovska, Yousra Laouarem, Marie-Eve Mayeur, Julien Ferent
Publikováno v:
Development. 146
Myelination leads to the formation of myelin sheaths surrounding neuronal axons and is crucial for function, plasticity and repair of the central nervous system (CNS). It relies on the interaction of the axons and the oligodendrocytes: the glial cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d4f6b00578939dbfbea779b59e7c2a5
https://doi.org/10.1242/dev.172502
https://doi.org/10.1242/dev.172502
Autor:
Elisabeth Traiffort, Julien Ferent
Publikováno v:
médecine/sciences. 31:1115-1125
Development and repair of the nervous system are based on the existence of neural stem cells (NSCs) able to generate neurons and glial cells. Among the mechanisms that are involved in the control of embryo or adult NSCs, the Notch signalling plays a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70db91a7aee6a0528e33955fba8dd891
https://doi.org/10.1051/medsci/20153112015
https://doi.org/10.1051/medsci/20153112015
Autor:
Louise, Thiry, Chloé, Lemaire, Ali, Rastqar, Maxime, Lemieux, Jimmy, Peng, Julien, Ferent, Marie, Roussel, Eric, Beaumont, James P, Fawcett, Robert M, Brownstone, Frédéric, Charron, Frédéric, Bretzner
Publikováno v:
eNeuro. 9(2)
Axon guidance receptors such as deleted in colorectal cancer (DCC) contribute to the normal formation of neural circuits, and their mutations can be associated with neural defects. In humans, heterozygous mutations in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::38aebb99acdd6b50dd8a2fc75df5834b
https://pubmed.ncbi.nlm.nih.gov/35115383
https://pubmed.ncbi.nlm.nih.gov/35115383
Autor:
Steves Morin, Shirin Makihara, Frédéric Charron, Patricia T. Yam, Jean-François Côté, Julien Ferent
Publikováno v:
Developmental cell. 46(4)
Summary In the developing spinal cord, Sonic hedgehog (Shh) attracts commissural axons toward the floorplate. How Shh regulates the cytoskeletal remodeling that underlies growth cone turning is unknown. We found that Shh-mediated growth cone turning
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8556b0a7f9cc136ddb8eb1499ae92131
https://pubmed.ncbi.nlm.nih.gov/30078728
https://pubmed.ncbi.nlm.nih.gov/30078728