Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Julien E. Gautrot"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Microfabricated organ-on-a-chips are rapidly becoming the gold standard for the testing of safety and efficacy of therapeutics. A broad range of designs has emerged, but recreating microvascularised tissue models remains difficult in many ca
Externí odkaz:
https://doaj.org/article/e389f9a68ca5476bb645cfadc3c071bb
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Recapitulating the normal physiology of the microvasculature is pivotal in the development of more complex in-vitro models and organ-on-chip designs. Pericytes are an important component of the vasculature, promoting vessel stability, inhibi
Externí odkaz:
https://doaj.org/article/f0fc5020034345f5bdddfcf09c87d820
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Factors controlling release of loaded cargo from polycationic gene delivery vectors are still poorly understood. Here, the authors report on a study of mechanisms of RNA release, highlighting the role of competitive binding, and characterise the inte
Externí odkaz:
https://doaj.org/article/77e09c05fccf4710b25bf87fca6c7bd8
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Tissue-engineered skin constructs have been under development since the 1980s as a replacement for human skin tissues and animal models for therapeutics and cosmetic testing. These have evolved from simple single-cell assays to increasingly complex m
Externí odkaz:
https://doaj.org/article/b63406aeb52041aea0f19094f883ffa1
Autor:
Keitel Cervantes-Salguero, Yair Augusto Gutiérrez Fosado, William Megone, Julien E. Gautrot, Matteo Palma
Publikováno v:
Molecules, Vol 28, Iss 9, p 3686 (2023)
DNA is programmed to hierarchically self-assemble into superstructures spanning from nanometer to micrometer scales. Here, we demonstrate DNA nanosheets assembled out of a rationally designed flexible DNA unit (F-unit), whose shape resembles a Feynma
Externí odkaz:
https://doaj.org/article/de57875eeaca4a8083196ee4e8bbe597
Publikováno v:
Nanocomposites, Vol 7, Iss 1, Pp 1-34 (2021)
Electrospun fibers have received significant interests for various application areas such as filtration, composites and biomedical products due to their large surface area, good continuity, high porosity and many other unique properties. In bio-relat
Externí odkaz:
https://doaj.org/article/6807b628f839435eb0b7d72e5aaa6008
Publikováno v:
Nanocomposites, Vol 6, Iss 3, Pp 85-98 (2020)
Carboxy-methyl-cellulose (CMC) hydrogels, prepared in the presence of a crosslinker and photoinitiator, were reinforced with 3.7 wt% electrospun PLA fibers to create CMC hydrogel composites. To improve fiber-matrix adhesion, electrospun fiber mats ba
Externí odkaz:
https://doaj.org/article/a4e9d12f9749489d8b966f0584ffcf0e
Autor:
Lihui Peng, Julien E. Gautrot
Publikováno v:
Materials Today Bio, Vol 12, Iss , Pp 100159- (2021)
Tremendous progress in the identification, isolation and expansion of stem cells has allowed their application in regenerative medicine and tissue engineering, and their use as advanced in vitro models. As a result, stem cell manufacturing increasing
Externí odkaz:
https://doaj.org/article/ccf6b5382226476ba1bad9e12d6637d9
Autor:
Atiya M. Sarmin, Nadia El Moussaid, Ratima Suntornnond, Eleanor J. Tyler, Yang-Hee Kim, Stefania Di Cio, William V. Megone, Oliver Pearce, Julien E. Gautrot, Jonathan Dawson, John T. Connelly
Publikováno v:
Biomolecules, Vol 12, Iss 6, p 837 (2022)
The extracellular matrix (ECM) is a complex mixture of structural proteins, proteoglycans, and signaling molecules that are essential for tissue integrity and homeostasis. While a number of recent studies have explored the use of decellularized ECM (
Externí odkaz:
https://doaj.org/article/8cb50e48df024102aa910c73c6481901
Autor:
Anureet Kaur, Julien E. Gautrot, Gabriel Cavalli, Douglas Watson, Alan Bickley, Keizo Akutagawa, James J. C. Busfield
Publikováno v:
Polymers, Vol 13, Iss 19, p 3347 (2021)
The introduction of dynamic bonds capable of mediating self-healing in a fully cross-linked polychloroprene network can only occur if the reversible moieties are carried by the cross-linker itself or within the main polymer backbone. Conventional cro
Externí odkaz:
https://doaj.org/article/8ca46497fff547fea7836dc5fa8894d3