Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Julien Delile"'
Autor:
Kenzo Ivanovitch, Pablo Soro-Barrio, Probir Chakravarty, Rebecca A Jones, Donald M Bell, S Neda Mousavy Gharavy, Despina Stamataki, Julien Delile, James C Smith, James Briscoe
Publikováno v:
PLoS Biology, Vol 19, Iss 5, p e3001200 (2021)
The heart develops from 2 sources of mesoderm progenitors, the first and second heart field (FHF and SHF). Using a single-cell transcriptomic assay combined with genetic lineage tracing and live imaging, we find the FHF and SHF are subdivided into di
Externí odkaz:
https://doaj.org/article/a5429e0ee4a848d2b0cec818d86e57c3
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Embryonic development is a complex process where genetic and biochemical information direct morphogenesis. Here the authors describe MecaGen, an agent-based model and simulation platform of multicellular development designed to allow a quantitative c
Externí odkaz:
https://doaj.org/article/cccbae085a244c23941a41eb597b8505
Autor:
Andreas Sagner, Zachary B Gaber, Julien Delile, Jennifer H Kong, David L Rousso, Caroline A Pearson, Steven E Weicksel, Manuela Melchionda, S Neda Mousavy Gharavy, James Briscoe, Bennett G Novitch
Publikováno v:
PLoS Biology, Vol 16, Iss 2, p e2003127 (2018)
During tissue development, multipotent progenitors differentiate into specific cell types in characteristic spatial and temporal patterns. We addressed the mechanism linking progenitor identity and differentiation rate in the neural tube, where motor
Externí odkaz:
https://doaj.org/article/84aadd8ec59747d7be20f2ba715fe14d
The vertebrate inner ear arises from a pool of progenitors with the potential to contribute to all the sense organs and cranial ganglia in the head. Here we explore the molecular mechanisms that control ear specification from these precursors. Using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::708c5b79ca169adcaa3ab60191bb7500
https://doi.org/10.1101/2021.04.20.440617
https://doi.org/10.1101/2021.04.20.440617
Autor:
James Briscoe, Manuela Melchionda, Andreas Sagner, Teresa Rayon, Julien Delile, Amelia Edwards
Publikováno v:
Development (Cambridge, England)
Delile, J, Rayon, T, Melchionda, M, Edwards, A, Briscoe, J & Sagner, A 2019, ' Single cell transcriptomics reveals spatial and temporal dynamics of gene expression in the developing mouse spinal cord ', Development, vol. 146, no. 12, dev173807 . https://doi.org/10.1242/dev.173807
Development
Delile, J, Rayon, T, Melchionda, M, Edwards, A, Briscoe, J & Sagner, A 2019, ' Single cell transcriptomics reveals spatial and temporal dynamics of gene expression in the developing mouse spinal cord ', Development, vol. 146, no. 12, dev173807 . https://doi.org/10.1242/dev.173807
Development
The coordinated spatial and temporal regulation of gene expression in the vertebrate neural tube determines the identity of neural progenitors and the function and physiology of the neurons they generate. Progress has been made deciphering the gene r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fb5b8c27b95aec6d6a233008efe670e
http://europepmc.org/articles/PMC6602353
http://europepmc.org/articles/PMC6602353
Autor:
Pablo Soro-Barrio, Kenzo Ivanovitch, James Briscoe, Donald M. Bell, James C. Smith, Rebecca A. Jones, Probir Chakravarty, Despina Stamataki, S. Neda Mousavy Gharavy, Julien Delile
Publikováno v:
PLoS Biology
PLoS Biology, Vol 19, Iss 5, p e3001200 (2021)
PLoS Biology, Vol 19, Iss 5, p e3001200 (2021)
The heart develops from 2 sources of mesoderm progenitors, the first and second heart field (FHF and SHF). Using a single-cell transcriptomic assay combined with genetic lineage tracing and live imaging, we find the FHF and SHF are subdivided into di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ae3ab4f74c043e15f3f2b531569f7ad
https://doi.org/10.1371/journal.pbio.3001200
https://doi.org/10.1371/journal.pbio.3001200
Autor:
Julien Delile, Yali Huang, Mina Gouti, Jens Kleinjung, James Briscoe, Filip J. Wymeersch, Valerie Wilson, Despina Stamataki
Publikováno v:
Developmental Cell
Gouti, M, Delile, J, Stamataki, D, Wymeersch, F J, Huang, Y, Kleinjung, J, Wilson, V & Briscoe, J 2017, ' A gene regulatory network balances neural and mesoderm specification during vertebrate trunk development ', Developmental Cell, vol. 41, no. 3, E7, pp. 243-261 . https://doi.org/10.1016/j.devcel.2017.04.002
Gouti, M, Delile, J, Stamataki, D, Wymeersch, F J, Huang, Y, Kleinjung, J, Wilson, V & Briscoe, J 2017, ' A gene regulatory network balances neural and mesoderm specification during vertebrate trunk development ', Developmental Cell, vol. 41, no. 3, E7, pp. 243-261 . https://doi.org/10.1016/j.devcel.2017.04.002
Summary Transcriptional networks, regulated by extracellular signals, control cell fate decisions and determine the size and composition of developing tissues. One example is the network controlling bipotent neuromesodermal progenitors (NMPs) that fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9356a325e05d424529adc012c9959d7d
https://doi.org/10.1016/j.devcel.2017.04.002
https://doi.org/10.1016/j.devcel.2017.04.002
We propose a theoretical, yet realistic agent-based model and simulation platform of animal embryogenesis, called MecaGen, 1 centered on the physico-chemical coupling of cell mechanics with gene expression and molecular signaling. This project aims t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be0dcff0932d270d3eacaab05c3646f1
https://doi.org/10.1016/b978-0-12-405926-9.00016-2
https://doi.org/10.1016/b978-0-12-405926-9.00016-2
Publikováno v:
FASEB Journal
Experimental Biology Meeting 2011
Experimental Biology Meeting 2011, Amer Assoc Anatomists (AAA); Amer Physiolog Soc (APS); Amer Soc Biochem & Mol Biol (ASBMB); Amer Soc Investigat Pathol (ASIP); Amer Soc Nutrit (ASN); Amer Soc Pharmacol & Expt Therapeut (ASPET), Apr 2011, Washington, United States. Meeting Abstarcts supplement 9.4
Experimental Biology Meeting 2011
Experimental Biology Meeting 2011, Amer Assoc Anatomists (AAA); Amer Physiolog Soc (APS); Amer Soc Biochem & Mol Biol (ASBMB); Amer Soc Investigat Pathol (ASIP); Amer Soc Nutrit (ASN); Amer Soc Pharmacol & Expt Therapeut (ASPET), Apr 2011, Washington, United States. Meeting Abstarcts supplement 9.4
International audience; We present a theoretical model of animal morphogenesis construed as a self-organized phenomenon emerging from a complex system made of a myriad of individual cell behaviors. It is implemented in an agent-based simulation cente
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e48ccd2fa66f377303573155a6781868
https://hal.archives-ouvertes.fr/hal-01179864
https://hal.archives-ouvertes.fr/hal-01179864