Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Julien Camperi"'
Autor:
Haoqian Liang, Qiang Wu, Xinzheng Victor Guo, Linda Chan, Tin Mao, Cinzia Stella, Axel Guilbaud, Julien Camperi
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12889 (2023)
Phagocytosis is one of the key functions of retinal pigment epithelium (RPE) cells, which maintain photoreceptor health by removing photoreceptor outer segments (POSs) that are regularly shed. A deficiency in RPE function to phagocytose POSs may lead
Externí odkaz:
https://doaj.org/article/24c99336ab5547f5a76f201d6bbb5079
Autor:
Y. Diana Liu, Lance Cadang, Karenna Bol, Xiao Pan, Katherine Tschudi, Mansour Jazayri, Julien Camperi, David Michels, John Stults, Reed J. Harris, Feng Yang
Publikováno v:
Bioengineering, Vol 9, Iss 11, p 641 (2022)
Heterogeneity of therapeutic Monoclonal antibody (mAb) drugs are due to protein variants generated during the manufacturing process. These protein variants can be critical quality attributes (CQAs) depending on their potential impact on drug safety a
Externí odkaz:
https://doaj.org/article/d370de7b03fd43aeb9925b08521855a3
Autor:
Bingchuan Wei, Xuan Gao, Lance Cadang, Saeed Izadi, Peilu Liu, Hui-Min Zhang, Elizabeth Hecht, Jeongsup Shim, Gordon Magill, Juan Rincon Pabon, Lu Dai, Wilson Phung, Elaine Lin, Christopher Wang, Kevin Whang, Sean Sanchez, Jose Oropeza Jr, Julien Camperi, Jennifer Zhang, Wendy Sandoval, Yonghua Taylor Zhang, Guoying Jiang
Publikováno v:
mAbs, Vol 13, Iss 1 (2021)
Fc galactosylation is a critical quality attribute for anti-tumor recombinant immunoglobulin G (IgG)-based monoclonal antibody (mAb) therapeutics with complement-dependent cytotoxicity (CDC) as the mechanism of action. Although the correlation betwee
Externí odkaz:
https://doaj.org/article/bdd3b615610e438ebfe86ec19cb0df05
Autor:
Kilian Mayr, Thomas Weindl, Achim Gärtner, Julien Camperi, Thomas Maetzke, Markus Förster, Thomas Nachtigall, Frank Steiner, Annette Vogt, Fabian Hosp, Michael Mølhøj
Publikováno v:
Analytical Chemistry. 95:3629-3637
Autor:
Patricia Molina, Julien Camperi
Publikováno v:
LCGC North America. :11-15
Identification, monitoring, and, more importantly, linkage of critical quality attributes (CQAs) in processing parameters in a biopharmaceutical product is required to ensure the quality and manufacturing consistency of the product, but also its safe
Autor:
Julien Camperi
Publikováno v:
LCGC North America. :20-22,29
Online monitoring of critical quality attributes (CQAs) directly within the bioreactor can provide the basis for advanced processing of therapeutics production, including automated real-time monitoring, feedback control process intensification, smart
Publikováno v:
Analytical Chemistry. 94:1432-1440
Advances in gene-editing technology enable efficient, targeted
Publikováno v:
Journal of Immunological Methods. 517:113491
Autor:
Julien Camperi, Gary Console, Laura Zheng, Nicole Stephens, Mary Montti, Brian Roper, Minhua Zheng, Maryam Moshref, Yavuz Dagdas, Patrick Holder, Cinzia Stella
Publikováno v:
Talanta. 252
CRISPR (clustered regularly interspaced short palindromic repeats)-associated proteins (Cas) are powerful gene-editing tools used in therapeutic applications. Efforts to minimize off-target cleavage by CRISPR-Cas9 have motivated the development of en
Autor:
Julien Camperi, Audrey Combès, Nathalie Delaunay, Valérie Pichon, Thierry Fournier, Amira Al Matari
Publikováno v:
Analytical and Bioanalytical Chemistry
Analytical and Bioanalytical Chemistry, Springer Verlag, 2020, 412 (23), pp.5729-5741. ⟨10.1007/s00216-020-02794-3⟩
Analytical and Bioanalytical Chemistry, 2020, 412 (23), pp.5729-5741. ⟨10.1007/s00216-020-02794-3⟩
Analytical and Bioanalytical Chemistry, Springer Verlag, 2020, 412 (23), pp.5729-5741. ⟨10.1007/s00216-020-02794-3⟩
Analytical and Bioanalytical Chemistry, 2020, 412 (23), pp.5729-5741. ⟨10.1007/s00216-020-02794-3⟩
International audience; Human chorionic gonadotropin (hCG) and follicle-stimulating hormone (FSH) belong to the family of glycoprotein polypeptide hormones called gonadotropins. They are heterodimers sharing the α-subunit structure that has 2 N-glyc