Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Julien Bruban"'
Autor:
Julien Bruban, Agathe Maoui, Naïma Chalour, Na An, Laurent Jonet, Charles Feumi, Jacques Tréton, Florian Sennlaub, Francine Behar-Cohen, Frédéric Mascarelli, Virginie Dinet
Publikováno v:
Neurobiology of Disease, Vol 42, Iss 1, Pp 55-72 (2011)
Age-related macular degeneration is characterized by the formation of drusen containing amyloid-β (Aβ) and the degeneration of photoreceptors. To explore the largely unknown role of Aβ in the retina, we investigated the effects on photoreceptors o
Externí odkaz:
https://doaj.org/article/d34290eefbef407a85c4d59ec386f792
Autor:
Anastasios Georgakopoulos, Nikolaos K. Robakis, Jindong Xu, Zhao Xuan, Julien Bruban, Junichi Shioi, Gael Barthet
Publikováno v:
Journal of Biological Chemistry. 288:30495-30501
Abnormally high concentrations of extracellular glutamate in the brain may cause neuronal damage via excitotoxicity. Thus, tight regulation of glutamate release is critical to neuronal function and survival. Excitotoxicity is caused mainly by overact
Autor:
Christophe Klein, Agathe Maoui, Virginie Dinet, Julien Bruban, Na An, Naima Chalour, Francine Behar-Cohen, Laurent Jonet, Alain Buret, Jacques Tréton, Frédéric Mascarelli
Publikováno v:
Aging Cell. 11:683-693
Summary In normal retinas, amyloid-β (Aβ) accumulates in the subretinal space, at the interface of the retinal pigment epithelium, and the photoreceptor outer segments. However, the molecular and cellular effects of subretinal Aβ remain inadequate
Autor:
Francine Behar-Cohen, Julien Bruban, Agathe Maoui, Naima Chalour, Florian Sennlaub, Na An, Jacques Tréton, Virginie Dinet, Laurent Jonet, Charles Feumi, Frédéric Mascarelli
Publikováno v:
Neurobiology of Disease, Vol 42, Iss 1, Pp 55-72 (2011)
Age-related macular degeneration is characterized by the formation of drusen containing amyloid-β (Aβ) and the degeneration of photoreceptors. To explore the largely unknown role of Aβ in the retina, we investigated the effects on photoreceptors o
Autor:
Julien Bruban, Laurent Jonet, Frédéric Mascarelli, Na An, Anne-Lise Glotin, Naima Chalour, Virginie Dinet, Anne Marie Faussat, Florian Sennlaub
Publikováno v:
Aging Cell. 8:162-177
Age-related macular degeneration (AMD) is characterized by the formation of drusen, extracellular deposits associated with atrophy of the retinal pigmented epithelium (RPE), disturbance of the transepithelial barrier and photoreceptor death. Amyloid-
Autor:
Zhiping Shao, Anastasios Georgakopoulos, Yuji Kajiwara, Junichi Shioi, Yonejung Yoon, Qian Huang, Georgios Voloudakis, Julien Bruban, Nikolaos K. Robakis, Miguel A. Gama Sosa, Al Rahim
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 29(9)
Epidermal growth factor receptor (EGFR) plays pivotal roles in cell proliferation, differentiation, and tissue development, while EGFs protect neurons from toxic insults by binding EGFR and stimulating survival signaling. Furthermore, recent evidence
Publikováno v:
Alzheimer's & Dementia. 9
Autor:
Virginie, Dinet, Julien, Bruban, Naima, Chalour, Agathe, Maoui, Na, An, Laurent, Jonet, Alain, Buret, Francine, Behar-Cohen, Christophe, Klein, Jacques, Tréton, Frédéric, Mascarelli
Publikováno v:
Aging cell. 11(4)
In normal retinas, amyloid-β (Aβ) accumulates in the subretinal space, at the interface of the retinal pigment epithelium, and the photoreceptor outer segments. However, the molecular and cellular effects of subretinal Aβ remain inadequately eluci
Autor:
Zhiping Shao, Nikolaos K. Robakis, Julien Bruban, Jindong Xu, Junichi Shioi, Julie Dunys, Anastasios Georgakopoulos, Gweltas Mauger, Yimin Ren, Gael Barthet, Zhao Xuan, Nicolas Arbez
Publikováno v:
Neurobiology of aging. 34(2)
Activation of EphB receptors by ephrinB (efnB) ligands on neuronal cell surface regulates important functions, including neurite outgrowth, axonal guidance, and synaptic plasticity. Here, we show that efnB rescues primary cortical neuronal cultures f
Publikováno v:
Advances in experimental medicine and biology. 723