Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Julien A. Boos"'
Autor:
Michael Beverly, Jeremy Baryza, Chandra Vargeese, Olivier Heudi, Thomas Faller, Jürg Hunziker, Julien A. Boos, Karine Litherland, Markus Stoeckli, Piet Swart, Keith Bowman, Francois Natt, Iwan Beuvink, Esther van de Kerkhof, Jesper Christensen, Joel Krauser
Publikováno v:
Drug Metabolism and Disposition. 42:431-440
Absorption, distribution, metabolism, and excretion properties of a small interfering RNA (siRNA) formulated in a lipid nanoparticle (LNP) vehicle were determined in male CD-1 mice following a single intravenous administration of LNP-formulated [(3)H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de4d9490ba4aec0852d6e9059a6ec750
https://doi.org/10.1124/dmd.113.055434
https://doi.org/10.1124/dmd.113.055434
Autor:
Julien A. Boos, Iwan Beuvink
Publikováno v:
Methods in Molecular Biology ISBN: 9781493931477
Characterizing the in vivo biodistribution pattern and relative expression levels of oligonucleotide-based molecules such as mRNA, miRNA, siRNA, and anti-miRNAs in animal models, could be a helpful first-step in the successful development of therapeu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd26f67e99acf74e69179299d98523f3
https://doi.org/10.1007/978-1-4939-3148-4_8
https://doi.org/10.1007/978-1-4939-3148-4_8
Autor:
Julien A, Boos, Iwan, Beuvink
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1372
Characterizing the in vivo biodistribution pattern and relative expression levels of oligonucleotide-based molecules such as mRNA, miRNA, siRNA, and anti-miRNAs in animal models, could be a helpful first-step in the successful development of therapeu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0d246ddb455287d1533a6d935f8df3b7
https://pubmed.ncbi.nlm.nih.gov/26530918
https://pubmed.ncbi.nlm.nih.gov/26530918
Autor:
Michael Beverly, Armin Beyerbach, Karine Litherland, David Morrissey, Julien A. Boos, Mari-Luz Piccolotto, Piet Swart, Juerg Hunziker, Andre Dattler, Werner Zuercher, Thomas Faller, Sandro Gfeller, David W. Kirk, Iwan Beuvink, Fabian Von Arx, Esther van de Kerkhof, Jesper Christensen, Philippe Neuner, William Leonard Wishart
Publikováno v:
Nucleic Acids Research
Efficient tissue-specific delivery is a crucial factor in the successful development of therapeutic oligonucleotides. Screening for novel delivery methods with unique tissue-homing properties requires a rapid, sensitive, flexible and unbiased techniq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19fbeae90599d659168cb139bc7414fc
https://doi.org/10.1093/nar/gkt515
https://doi.org/10.1093/nar/gkt515