Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Julien, Gibon"'
Autor:
Stephen D. Glasgow, Teddy A.J. Fisher, Edwin W. Wong, Kevin Lançon, Kira M. Feighan, Ian V. Beamish, Julien Gibon, Philippe Séguéla, Edward S. Ruthazer, Timothy E. Kennedy
Publikováno v:
Cell Reports, Vol 43, Iss 2, Pp 113812- (2024)
Summary: The ability of the mammalian brain to maintain spatial representations of external or internal information for short periods of time has been associated with sustained neuronal spiking and reverberatory neural network activity in the medial
Externí odkaz:
https://doaj.org/article/174874b08ee846af9d11921e5d716470
Autor:
Dylan E Da Silva, Christy M Richards, Seamus A McRae, Ishvin Riar, Sijie Shirley Yang, Noah E Zurfluh, Julien Gibon, Andis Klegeris
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0298748 (2024)
Although histone proteins are widely known for their intranuclear functions where they organize DNA, all five histone types can also be released into the extracellular space from damaged cells. Extracellular histones can interact with pattern recogni
Externí odkaz:
https://doaj.org/article/86f6608f38eb4fdabdbc208c7d13b267
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Axons that are physically separated from their soma activate a series of signaling events that results in axonal self-destruction. A critical element of this signaling pathway is an intra-axonal calcium rise that occurs just prior to axonal fragmenta
Externí odkaz:
https://doaj.org/article/8cbc0899b67144349baef6a42e2ad8ed
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 16 (2022)
The p75 neurotrophin receptor (p75NTR) is implicated in various biological functions during development and adulthood. Several animal models have been developed to identify the roles of p75NTR in vivo and in vitro. P75NTRExonIII knock-out mice are wi
Externí odkaz:
https://doaj.org/article/eb9dcbeeeb72419eb0be9d14720a530c
Autor:
Taryn E. Murray, Tyler J. Wenzel, Svetlana Simtchouk, Bridget K. Greuel, Julien Gibon, Andis Klegeris
Publikováno v:
Mediators of Inflammation, Vol 2022 (2022)
Alzheimer’s disease (AD) is characterized by chronic neuroinflammation, which is partially mediated by dysregulated functions of glial cells. Cardiolipin (CL) is a phospholipid normally confined to the inner mitochondrial membrane; however, it has
Externí odkaz:
https://doaj.org/article/c72ce61d88be4583ab88add5cde3e38e
Publikováno v:
J Neurosci
The activation of self-destructive cellular programs helps sculpt the nervous system during development, but the molecular mechanisms used are not fully understood. Prior studies have investigated the role of the APP in the developmental degeneration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3463a4ac007dafe9282566d85fa23a5
https://doi.org/10.1523/jneurosci.0162-22.2022
https://doi.org/10.1523/jneurosci.0162-22.2022
Autor:
Stephen D. Glasgow, Simon Labrecque, Ian V. Beamish, Sarah Aufmkolk, Julien Gibon, Dong Han, Stephanie N. Harris, Paul Dufresne, Paul W. Wiseman, R. Anne McKinney, Philippe Séguéla, Paul De Koninck, Edward S. Ruthazer, Timothy E. Kennedy
Publikováno v:
Cell Reports, Vol 25, Iss 1, Pp 168-182.e6 (2018)
Summary: Dynamic trafficking of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid glutamate receptors (AMPARs) to synapses is critical for activity-dependent synaptic plasticity underlying learning and memory, but the identity of key molecular ef
Externí odkaz:
https://doaj.org/article/4819f5451c2f41fbaa1a2aa9e81065b0
Autor:
Aaron D Johnstone, Robin M Hallett, Andrés de Léon, Bruno Carturan, Julien Gibon, Philip A Barker
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0199570 (2018)
Axons normally degenerate during development of the mammalian nervous system, but dysregulation of the same genetically-encoded destructive cellular machinery can destroy crucial structures during adult neurodegenerative diseases. Nerve growth factor
Externí odkaz:
https://doaj.org/article/6268038ca52446609ffc32b01461f43d
Autor:
Tyler J. Wenzel, Taryn E. Murray, Benjamin Noyovitz, Kamal Narayana, Taylor E. Gray, Jennifer Le, Jim He, Svetlana Simtchouk, Julien Gibon, Jane Alcorn, Darrell D. Mousseau, Wesley F. Zandberg, Andis Klegeris
Publikováno v:
Molecular and cellular neurosciences.
Cardiolipin is a mitochondrial phospholipid that is also detected in serum inferring its extracellular release; however, this process has not been directly demonstrated for any of the brain cell types. Nevertheless, extracellular cardiolipin has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6fc8435e26f7337d3caa6b6f7fccd7f
https://pubmed.ncbi.nlm.nih.gov/36592800
https://pubmed.ncbi.nlm.nih.gov/36592800
Publikováno v:
Brain Research. 1807:148315
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::666d0c5d2f7a97db4bc4bbd177325444
https://doi.org/10.1016/j.brainres.2023.148315
https://doi.org/10.1016/j.brainres.2023.148315