Zobrazeno 1 - 10
of 217
pro vyhledávání: '"Julie de Backer"'
Autor:
Maximilian A. Selbst, Colin R. Ward, Megan L. Svetgoff, Hector I. Michelena, Anna Sabate-Rotes, Julie De Backer, Laura Muiño Mosquera, Anji T. Yetman, Malenka M. Bissell, Maria Grazia Andreassi, Ilenia Foffa, Dawn S. Hui, Anthony Caffarelli, Yuli Y. Kim, Dongchuan Guo, Rodolfo Citro, Margot De Marco, Justin T. Tretter, Shaine A. Morris, Kim L. McBride, Simon C. Body, Siddharth K. Prakash
Publikováno v:
Hearts, Vol 5, Iss 3, Pp 253-258 (2024)
Bicuspid aortic valve (BAV) is the most common congenital heart malformation in adults, but it can also cause childhood-onset complications. The presentation and clinical course of young adults who present due to BAV complications are relatively unch
Externí odkaz:
https://doaj.org/article/5648bbbc963b4790a6094237ffd36854
Autor:
Kishan L. Asokan, Jennifer R. Landes, Wannes Renders, Laura Muiño Mosquera, Julie De Backer, David W. Jantzen, Anji T. Yetman, Gisela Teixido‐Tura, Arturo Evangelista, Richmond Jeremy, Edward G. Jones, Shaine Morris, Tam Doan, Maral Ouzonian, Alan Braverman, Guillaume Jondeau, Olivier Milleron, Dianna M. Milewicz, Siddharth K. Prakash
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 21 (2024)
Background Mitral annular disjunction (MAD), posterior displacement of the mitral valve leaflet hinge point, predisposes to arrhythmias or sudden cardiac death. We evaluated the burden of MAD, mitral valve prolapse (MVP), and mitral regurgitation (MR
Externí odkaz:
https://doaj.org/article/6412c93cdefe495f925a1a5d4ad6db2b
Autor:
Steven G Carlisle, Hasan Albasha, Hector I Michelena, Anna Sabate-Rotes, Lisa Bianco, Julie De Backer, Laura Muiño Mosquera, Anji T Yetman, Malenka M Bissell, Maria Grazia Andreassi, Ilenia Foffa, Dawn S Hui, Anthony Caffarelli, Yuli Y Kim, Dongchuan Guo, Rodolfo Citro, Margot De Marco, Justin T Tretter, Kim L McBride, Dianna M Milewicz, Simon C Body, Siddharth K Prakash, EBAV Investigators, BAVCon Investigators
Publikováno v:
PLoS ONE, Vol 19, Iss 9, p e0304514 (2024)
Bicuspid aortic valve (BAV), the most common congenital heart defect, is a major cause of aortic valve disease requiring valve interventions and thoracic aortic aneurysms predisposing to acute aortic dissections. The spectrum of BAV ranges from early
Externí odkaz:
https://doaj.org/article/242c32ad450e4d989ceb2ddbfe7c7ae9
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 10, Iss 12, p 492 (2023)
Over the past 50 years, there has been a major shift in age distribution of patients with congenital heart disease (CHD) thanks to significant advancements in medical and surgical treatment. Patients with CHD are, however, never cured and face unique
Externí odkaz:
https://doaj.org/article/15d79cf05cfa444f9e1c747c3662ab0e
Autor:
Jeffrey Aalders, Laurens Léger, Anthony Demolder, Laura Muiño Mosquera, Paul Coucke, Björn Menten, Julie De Backer, Jolanda van Hengel
Publikováno v:
Stem Cell Research, Vol 67, Iss , Pp 103036- (2023)
Marfan syndrome is an autosomal dominant genetic disorder resulting from pathogenic variants in FBN1 gene. FBN1 encodes for fibrillin-1, an important extracellular matrix protein. Impaired fibrillin-1 affects multiple organ systems, including the car
Externí odkaz:
https://doaj.org/article/8fb41cfcc7454bccb41cffab74b956df
Autor:
Andrea de la Fuente-Alonso, Marta Toral, Alvaro Alfayate, María Jesús Ruiz-Rodríguez, Elena Bonzón-Kulichenko, Gisela Teixido-Tura, Sara Martínez-Martínez, María José Méndez-Olivares, Dolores López-Maderuelo, Ileana González-Valdés, Eusebio Garcia-Izquierdo, Susana Mingo, Carlos E. Martín, Laura Muiño-Mosquera, Julie De Backer, J. Francisco Nistal, Alberto Forteza, Arturo Evangelista, Jesús Vázquez, Miguel R. Campanero, Juan Miguel Redondo
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Aortic aneurysm and dissection, the major problem linked to Marfan syndrome (MFS), lacks effective pharmacological treatment. Here, the authors show that the NO pathway is overactivated in MFS and that inhibition of guanylate cyclase and cGMP-depende
Externí odkaz:
https://doaj.org/article/439b8e5d5511412680725f97df82754a
Autor:
Laura Muiño-Mosquera, Hans De Wilde, Daniel Devos, Danilo Babin, Luc Jordaens, Anthony Demolder, Katya De Groote, Daniel De Wolf, Julie De Backer
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 15, Iss 1, Pp 1-11 (2020)
Abstract Background Aortic root dilatation and—dissection and mitral valve prolapse are established cardiovascular manifestations in Marfan syndrome (MFS). Heart failure and arrhythmic sudden cardiac death have emerged as additional causes of morbi
Externí odkaz:
https://doaj.org/article/44c42345486a4e2cb37838d67c6a8b5c
Autor:
Gerlinde Logghe, Bram Trachet, Patrick Segers, Julie De Backer, Joscha Mulorz, Philip Dueppers, Frank Vermassen, Hubert Schelzig, Isabelle Van Herzeele, Markus U. Wagenhäuser
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Objective: Thoracic endovascular aortic repair (TEVAR) for type B aortic dissection (TBAD) aims to induce false lumen (FL) thrombosis by sealing intimal tears between the true (TL) and the FL, and blocking the inflow into the FL. Incomplete thrombosi
Externí odkaz:
https://doaj.org/article/7e7c81ca2e6f4c5499fbded6f12344a6
Autor:
Laura Muiño-Mosquera, Julie De Backer
Publikováno v:
Frontiers in Pediatrics, Vol 9 (2021)
Genetic aortic diseases are a group of illnesses characterized by aortic aneurysms or dissection in the presence of an underlying genetic defect. They are part of the broader spectrum of heritable thoracic aortic disease, which also includes those ca
Externí odkaz:
https://doaj.org/article/bbfc3fe0769a42998b2c281966a99a09
Autor:
Ingrid M. B. H. van de Laar, Eloisa Arbustini, Bart Loeys, Erik Björck, Lise Murphy, Maarten Groenink, Marlies Kempers, Janneke Timmermans, Jolien Roos-Hesselink, Kalman Benke, Guglielmina Pepe, Barbara Mulder, Zoltan Szabolcs, Gisela Teixidó-Turà, Leema Robert, Yaso Emmanuel, Arturo Evangelista, Alessandro Pini, Yskert von Kodolitsch, Guillaume Jondeau, Julie De Backer
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 14, Iss 1, Pp 1-7 (2019)
Abstract The ACTA2 gene encodes for smooth muscle specific α-actin, a critical component of the contractile apparatus of the vascular smooth muscle cell. Pathogenic variants in the ACTA2 gene are the most frequently encountered genetic cause of non-
Externí odkaz:
https://doaj.org/article/28a3f413457f4d019b78d4411ab50cb3