Zobrazeno 1 - 10
of 589
pro vyhledávání: '"Julie Williams"'
Autor:
Thomas Lancaster, Byron Creese, Valentina Escott-Price, Ian Driver, Georgina Menzies, Zunera Khan, Anne Corbett, Clive Ballard, Julie Williams, Kevin Murphy, Hannah Chandler
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-10 (2023)
Abstract Background Genome-wide association studies demonstrate that Alzheimer’s disease (AD) has a highly polygenic architecture, where thousands of independent genetic variants explain risk with high classification accuracy. This AD polygenic ris
Externí odkaz:
https://doaj.org/article/887ce6f7032e423d92295e136af11d6b
Autor:
Dipen Patel, Yamiko Joseph Msosa, Tao Wang, Julie Williams, Omar G Mustafa, Siobhan Gee, Barbara Arroyo, Damian Larkin, Trevor Tiedt, Angus Roberts, Richard J B Dobson, Fiona Gaughran
Publikováno v:
JMIR Research Protocols, Vol 13, p e49548 (2024)
BackgroundSevere mental illnesses (SMIs), including schizophrenia, bipolar affective disorder, and major depressive disorder, are associated with an increased risk of physical health comorbidities and premature mortality from conditions including car
Externí odkaz:
https://doaj.org/article/4aff4ca5e138444fa868a63ccff6a617
Autor:
Aurora Veteleanu, Joshua Stevenson-Hoare, Samuel Keat, Nikoleta Daskoulidou, Henrik Zetterberg, Amanda Heslegrave, Valentina Escott-Price, Julie Williams, Rebecca Sims, Wioleta M. Zelek, Sarah M. Carpanini, Bryan Paul Morgan
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-18 (2023)
Abstract Background Alzheimer’s disease (AD) has been associated with immune dysregulation in biomarker and genome-wide association studies (GWAS). GWAS hits include the genes encoding complement regulators clusterin (CLU) and complement receptor 1
Externí odkaz:
https://doaj.org/article/59f3ff05f56e42c9a86a2a9c929c0db9
Autor:
Emma Shu Min Lim, Julie Williams, Philip Vlaskovsky, Demelza J. Ireland, Donna T. Geddes, Sharon L. Perrella
Publikováno v:
Children, Vol 11, Iss 6, p 655 (2024)
The effects of preterm birth, neonatal morbidities and environmental influences on infant sleep development is an important yet under-researched topic, with little known about normative sleep for infants born sick or preterm. The aim of this prospect
Externí odkaz:
https://doaj.org/article/190466333042400396677ad445d1137d
Autor:
Ramin Pajoumshariati, Lorna Ewart, Ville Kujala, Raymond Luc, Samantha Peel, Adam Corrigan, Heather Weber, Bramasta Nugraha, Pernille B. L. Hansen, Julie Williams
Publikováno v:
Advanced Science, Vol 10, Iss 33, Pp n/a-n/a (2023)
Abstract The function of the glomerulus depends on the complex cell–cell/matrix interactions and replication of this in vitro would aid biological understanding in both health and disease. Previous models do not fully reflect all cell types and int
Externí odkaz:
https://doaj.org/article/40d07dfc9c4243bab8676a40760b5937
Autor:
Emma Shu Min Lim, Julie Williams, Philip Vlaskovsky, Demelza J. Ireland, Donna Tracy Geddes, Sharon Lisa Perrella
Publikováno v:
Proceedings, Vol 93, Iss 1, p 13 (2023)
Infants born sick or preterm and admitted to the neonatal intensive care unit (NICU) face challenges to their sleep and the establishment of breastfeeding. The reported sleep patterns of NICU graduates are conflicting, and there is evidence of bi-dir
Externí odkaz:
https://doaj.org/article/6990393a57514db78b8ef7129d04418e
Autor:
Jiahui Hou, Jonathan L. Hess, Nicola Armstrong, Joshua C. Bis, Benjamin Grenier-Boley, Ida K. Karlsson, Ganna Leonenko, Katya Numbers, Eleanor K. O’Brien, Alexey Shadrin, Anbupalam Thalamuthu, Qiong Yang, Ole A. Andreassen, Henry Brodaty, Margaret Gatz, Nicole A. Kochan, Jean-Charles Lambert, Simon M. Laws, Colin L. Masters, Karen A. Mather, Nancy L. Pedersen, Danielle Posthuma, Perminder S. Sachdev, Julie Williams, the Alzheimer’s Disease Neuroimaging Initiative, Chun Chieh Fan, Stephen V. Faraone, Christine Fennema-Notestine, Shu-Ju Lin, Valentina Escott-Price, Peter Holmans, Sudha Seshadri, Ming T. Tsuang, William S. Kremen, Stephen J. Glatt
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Polygenic risk scores (PRSs) can boost risk prediction in late-onset Alzheimer’s disease (LOAD) beyond apolipoprotein E (APOE) but have not been leveraged to identify genetic resilience factors. Here, we sought to identify resilience-confe
Externí odkaz:
https://doaj.org/article/05a0a605763842d88fd8cbd81b52d67b
Autor:
Alexis Hofherr, Julie Williams, Li-Ming Gan, Magnus Söderberg, Pernille B. L. Hansen, Kevin J. Woollard
Publikováno v:
BMC Nephrology, Vol 23, Iss 1, Pp 1-17 (2022)
Abstract Diabetic kidney disease (DKD) is the leading cause of kidney failure worldwide. Mortality and morbidity associated with DKD are increasing with the global prevalence of type 2 diabetes. Chronic, sub-clinical, non-resolving inflammation contr
Externí odkaz:
https://doaj.org/article/441494f4155e41ac8b207d9608db287a
Autor:
Dipen Patel, Yamiko J Msosa, Tao Wang, Omar G Mustafa, Siobhan Gee, Julie Williams, Angus Roberts, Richard JB Dobson, Fiona Gaughran
Publikováno v:
BMC Medical Informatics and Decision Making, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract Background Improvements to the primary prevention of physical health illnesses like diabetes in the general population have not been mirrored to the same extent in people with serious mental illness (SMI). This work evaluates the technical f
Externí odkaz:
https://doaj.org/article/87df2320c7de4e18b3515ef6a729036c
Autor:
Ebenezer Oloyede, Bethany Mantell, Julie Williams, Serena Lai, Sameer Jauhar, David Taylor, James H. MacCabe, Robert Harland, Philip McGuire, Graham Blackman
Publikováno v:
Therapeutic Advances in Psychopharmacology, Vol 12 (2022)
Background: Clozapine is the only medication licenced for patients with psychosis that is resistant to conventional antipsychotic treatment. However, despite its effectiveness, it remains widely underutilised. One contributory factor for this may be
Externí odkaz:
https://doaj.org/article/3672b4c84fae4d33960b9e480d6baf3b