Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Julie Wangsa"'
Autor:
Laishun Chen, Parviz Ghahramani, Antonia Periclou, Nayra Gad, William M. Greenberg, Julie Wangsa, Ramesh Boinpally
Publikováno v:
Clinical Drug Investigation. 35:601-612
Levomilnacipran is a serotonin and norepinephrine reuptake inhibitor with balanced potency for the reuptake inhibition of norepinephrine and serotonin, approved in the USA for the treatment of major depressive disorder (MDD) in adults. We conducted s
Autor:
Partha Roy, Stefano Persiani, Abhijeet Jakate, Massimo D'Amato, Ram Kapil, Julie Wangsa, Lucio C. Rovati
Publikováno v:
Clinical Pharmacokinetics. 45:1177-1188
Dexloxiglumide is a potent and selective cholecystokinin type 1 (CCK1) receptor antagonist currently under development in a variety of diseases affecting the gastrointestinal tract such as gastro-oesophageal reflux disease, irritable bowel syndrome (
Autor:
Julie Wangsa, Stefano Persiani, Alpita Patel, Partha Roy, Ram Kapil, Abhijeet Jakate, Wattanaporn Abramowitz
Publikováno v:
British Journal of Clinical Pharmacology. 60:498-507
Aims Dexloxiglumide is a new CCK1 receptor antagonist under investigation for treatment of functional gastrointestinal disorders and is metabolized by CYP3A4 and CYP2C9. The objectives of these two separate randomized, two-period, two-treatment cross
Autor:
Alpita Patel, Julie Wangsa, Abhijeet Jakate, Ram Kapil, Partha Roy, Wattanaporn Abramowitz, Stefano Persiani
Publikováno v:
The Journal of Clinical Pharmacology. 45:329-336
This study was undertaken to evaluate the effect of dexloxiglumide, a selective cholecystokinin receptor antagonist, on the pharmacokinetics of a combination oral contraceptive (OC). A single-blind, placebo-controlled, 2-period crossover study was co
Autor:
William M. Greenberg, Antonia Periclou, Ramesh Boinpally, Laishun Chen, Parviz Ghahramani, Julie Wangsa
Publikováno v:
Clinical drug investigation. 34(5)
Levomilnacipran is a serotonin and norepinephrine reuptake inhibitor with greater potency for the reuptake inhibition of norepinephrine than of serotonin, approved in the USA for the treatment of major depressive disorder (MDD) in adults. A single-do
Autor:
Jun Wang, Giulio Maria Pasinetti, Henry Li, Julie Wangsa, Karishma Habbu, Anastasiya Dzhuan, Lindsay Knable, Harold M. Wright, Prashant Vempati, Lap Ho
Publikováno v:
Journal of Alzheimer's disease : JAD. 33(4)
Nebivolol is a selective β1 adrenergic receptor antagonist with nitric oxide-mediated vasodilatory properties utilized in the treatment of hypertension. Previously, nebivolol was shown to modulate amyloid-β protein precursor processing in vitro. In
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 40(9)
The pharmacokinetics, excretion, and metabolism of milnacipran were evaluated after oral administration of a 100-mg dose of [¹⁴C]milnacipran hydrochloride to healthy male subjects. The peak plasma concentration of unchanged milnacipran (∼240 ng/
Publikováno v:
Analytical Chemistry. 64:583-589
Naphtalenedisulfonate-acetonitrile as a mobile phase alone with a cross-linked amine-fluorocarbon polymer sillica column has shown to be an effective combination for the separation of aliphatic anionic surfactants. Indirect conductivity and photometr
Autor:
Neil D. Danielson, Julie Wangsa
Publikováno v:
Electroanalysis. 3:625-630
Surface passivation during oxidation of NADH at a fluorocarbon polymer-carbon paste electrode (CPE) was about 25% less than that of the glassy carbon or Nujol-oil CPE. After repeated injections of 1.5 mM NADH for 12 h, the Kel-F wax CPE maintained ab
Publikováno v:
Journal of Chromatography A. 544:187-199
The use of both fluoropolymers and their derivatives as well as fluorinated bonded phases on silica as high-performance liquid chromatography column packings is reviewed. In general, retention of small molecules is less on fluorocarbon phases as comp