Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Julie V. Nguyen"'
Autor:
Xinyu Wu, Margareta Go, Julie V. Nguyen, Nathan W. Kuchel, Bernadine G. C. Lu, Kathleen Zeglinski, Kym N. Lowes, Dale J. Calleja, Jeffrey P. Mitchell, Guillaume Lessene, David Komander, Matthew E. Call, Melissa J. Call
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Papain-like protease (PLpro) is an attractive drug target for SARS-CoV-2 because it is essential for viral replication, cleaving viral poly-proteins pp1a and pp1ab, and has de-ubiquitylation and de-ISGylation activities, affecting innate imm
Externí odkaz:
https://doaj.org/article/f2aa5295a8ff4f9095605b082b38d19a
Autor:
Assaf Elazar, Nicholas J Chandler, Ashleigh S Davey, Jonathan Y Weinstein, Julie V Nguyen, Raphael Trenker, Ryan S Cross, Misty R Jenkins, Melissa J Call, Matthew E Call, Sarel J Fleishman
Publikováno v:
eLife, Vol 11 (2022)
De novo-designed receptor transmembrane domains (TMDs) present opportunities for precise control of cellular receptor functions. We developed a de novo design strategy for generating programmed membrane proteins (proMPs): single-pass α-helical TMDs
Externí odkaz:
https://doaj.org/article/4c88ae4a5ecb43b5a0ea6b73ec898c18
Autor:
Ashleigh S Davey, Nicholas J Chandler, Assaf Elazar, Jonathan Y Weinstein, Julie V Nguyen, Raphael Trenker, Ryan S Cross, Misty R Jenkins, Melissa J Call, Matthew E Call, Sarel J Fleishman
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4ce287f2a8adb7c8e69e1136e455ef0
https://doi.org/10.7554/elife.75660.sa2
https://doi.org/10.7554/elife.75660.sa2
Autor:
Ashleigh S Davey, Nicholas J Chandler, Assaf Elazar, Jonathan Y Weinstein, Julie V Nguyen, Raphael Trenker, Ryan S Cross, Misty R Jenkins, Melissa J Call, Matthew E Call, Sarel J Fleishman
De novo-designed receptor transmembrane domains (TMDs) present opportunities for precise control of cellular receptor functions. We developed a de novo design strategy for generating programmed membrane proteins (proMPs): single-pass α-helical TMDs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc1b36bd8e211471015945ed39077f69
Autor:
Ashleigh S Davey, Sarel J. Fleishman, Jonathan Weinstein, Melissa J. Call, Raphael Trenker, Ryan S. Cross, Nicholas J. Chandler, Matthew E. Call, Julie V. Nguyen, Misty R. Jenkins, Assaf Elazar
De novo designed receptor transmembrane domains (TMDs) present opportunities for precise control of cellular receptor functions. We developed a de novo design strategy for generating programmed membrane proteins (proMPs): single-pass α-helical TMDs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::278a787a184c7796fc8ea0565ae6ae5a
https://doi.org/10.1101/2020.07.26.221598
https://doi.org/10.1101/2020.07.26.221598
Autor:
Melissa J. Call, Alan F. Rubin, Xinyu Wu, Matthew E. Call, Julie V. Nguyen, Stephen Wilcox, Raphael Trenker
Publikováno v:
The Journal of Biological Chemistry
Immune-stimulatory ligands, such as major histocompatibility complex molecules and the T-cell costimulatory ligand CD86, are central to productive immunity. Endogenous mammalian membrane-associated RING-CHs (MARCH) act on these and other targets to r