Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Julie Usala"'
Autor:
Sara K. Blaine, Lishu Zhang, Kristie A. Diamond, Vijay A. Ramchandani, Markus Heilig, Primavera A. Spagnolo, Monte J. Phillips, Melanie L. Schwandt, Reza Momenan, David T. George, Julie Usala
Publikováno v:
Alcoholism: Clinical and Experimental Research. 38:3024-3032
Positively reinforcing properties of alcohol are in part mediated by activation of the ventral striatum (VS). Alcohol-induced release of endogenous opioids is thought to contribute to this response. Preclinical studies show that the opioid antagonist
Autor:
David T. George, Erick Singley, Julie Usala, John C. Umhau, Christopher B. Geyer, Melanie L. Schwandt, Markus Heilig
Publikováno v:
Neuropsychopharmacology. 36:1178-1186
Modulation of alcohol craving induced by challenge stimuli may predict the efficacy of new pharmacotherapies for alcoholism. We evaluated two pharmacological challenges, the α(2)-adrenergic antagonist yohimbine, which reinstates alcohol seeking in r