Výsledky vyhledávání - "Julie Stepanek"

Association of tissue-specific changes in translation elongation after cyclosporin with changes in elongation factor 2 phosphorylation

Autor: Susan A. Queen, Julie Stepanek, William C. Buss

Publikováno v: Biochemical Pharmacology. 48:1459-1469

In studies of cyclosporin (CsA) toxicity in Sprague-Dawley rats, CsA administered in vivo produced tissue-specific, dose-dependent changes in microsomal translation throughout the bodies of the animals. The most pronounced translation inhibition was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d7d0f430f52e2daafed8a71034926d4
https://doi.org/10.1016/0006-2952(94)90571-1

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Lamb: International Marketing

Autor: Julie Stepanek Shiflett

Publikováno v: Encyclopedia of Animal Science ISBN: 9780429178061

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e75a58cdd3c8a727f61e08905b34b793
https://doi.org/10.1081/e-eas2-120023834

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Tissue specificity of translation inhibition in Sprague-Dawley rats following in vivo cyclosporin A

Autor: Julie Stepanek, William C. Buss

Publikováno v: International journal of immunopharmacology. 15(6)

We have shown that following the in vivo administration of cyclosporin A (CsA) to either male or female Sprague-Dawley rats, there is a time- and dose-dependent inhibition of translation elongation in renal microsomes. Experiments reported in this pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5b7dc6b531d9f6e0970fa6c2adaf01f
https://pubmed.ncbi.nlm.nih.gov/8407058

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Characterization of the inhibition of renal translation in the Sprague-Dawley rat following in vivo cyclosporin A

Autor: Julie Stepanek, William C. Buss

Publikováno v: International journal of immunopharmacology. 15(1)

“Run-off” translation assays in microsomes isolated from Sprague-Dawley rats were used to examine the capacity of cyclosporin A (CsA) to alter translation elongation. CsA added in vitro in concentrations of up to 100 μg/ml did not reduce “run-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fb449527ec27bc0ad0af4ceb1aa5505
https://pubmed.ncbi.nlm.nih.gov/8432624

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A new proposal for the mechanism of cyclosporine a nephrotoxicity. Inhibition of renal microsomal protein chain elongation following in vivo cyclosporine a

Autor: William C. Buss, Julie Stepanek, William M. Bennett

Publikováno v: Biochemical Pharmacology. 38:4085-4093

In this paper, we report experiments examining the effect of cyclosporine A on “run-off” translation in microsomes isolated from tissues of Sprague-Dawley rats. In microsomes isolated from rat brain, kidney and thymus, cyclosporine A added in vit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a952793223797c11ad23cb5fccc406f1
https://doi.org/10.1016/0006-2952(89)90690-4

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Studies on the mechanism of glucocorticoid hormone induced alterations in rat thymic transcription—II. Partial purification and characterization of RNA polymerases II from hydrocortisone and control vehicle treated animals

Autor: Piatt Mk, William C. Buss, Julie Stepanek, Kenneth Stalter

Publikováno v: Journal of Steroid Biochemistry. 28:129-138

In experiments designed to study the mechanism of glucocorticoid hormone induced reductions in rat thymic transcription, adrenalectomized rats were injected with hydrocortisone (50 mg/kg) or control vehicle 12 h prior to sacrifice. Thymic nuclei were

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2920b23f1f5eb70222631af93e226f3b
https://doi.org/10.1016/0022-4731(87)90368-2

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Effect of calcium channel antagonists on calcium uptake and release by isolated rat cardiac mitochondria

Autor: Linda J. McGuffee, William C. Buss, Julie Stepanek, Daniel D. Savage, Sally A. Little

Publikováno v: European Journal of Pharmacology. 152:247-253

The effects of calcium channel antagonists on Ca2+ uptake and Na+-induced Ca2+ release were studied in isolated rat cardiac mitochondria. Diltiazem, nitrendipine and nimodipine were more effective inhibitors of Na+-induced Ca2+ release (IC50 = 19-100

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5a503c375153527337566e726978fd2
https://doi.org/10.1016/0014-2999(88)90719-4

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Studies on the mechanism of glucocorticoid hormone induced alterations in rat thymic transcription—I. Evidence from reconstituted cross-over transcription assays that sequential increases and decreases in transcription are due to changes in the activity of rna polymerase ii rather than in the activity of chromatin template

Autor: Kenneth Stalter, Keith Piatt, Julie Stepanek, Thomas D. Barela, William C. Buss

Publikováno v: Journal of Steroid Biochemistry. 19:1695-1703

In experiments to determine the mechanism of glucocorticoid induced decreases in thymic transcription, adrenalectomized rats were injected with hydrocortisone (50 mg/kg) or vehicle. Thymic nuclei were used to prepare chromatins and soluble nuclear ex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d658caca527b8319ea525436f7b1fb03
https://doi.org/10.1016/0022-4731(83)90346-1

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