Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Julie S. Martin"'
Publikováno v:
BioTechniques, Vol 36, Iss 5, Pp 778-782 (2004)
Externí odkaz:
https://doaj.org/article/1707fcdf01cb4959abf4bb9b9fb8ac71
Autor:
Nigel J O'Neil, Julie S Martin, Jillian L Youds, Jordan D Ward, Mark I R Petalcorin, Anne M Rose, Simon J Boulton
Publikováno v:
PLoS Genetics, Vol 9, Iss 7, p e1003582 (2013)
The generation and resolution of joint molecule recombination intermediates is required to ensure bipolar chromosome segregation during meiosis. During wild type meiosis in Caenorhabditis elegans, SPO-11-generated double stranded breaks are resolved
Externí odkaz:
https://doaj.org/article/370aa933cc4c4013a58fa02ba8b07e8c
Autor:
Andrés Aguilera, Tatiana García-Muse, María L. García-Rubio, Jolanta Polanowska, Nicola O’Reilly, Simon J. Boulton, Ulises Galindo-Diaz, Julie S. Martin
Publikováno v:
Cell Reports
idUS. Depósito de Investigación de la Universidad de Sevilla
instname
Digital.CSIC. Repositorio Institucional del CSIC
idUS. Depósito de Investigación de la Universidad de Sevilla
instname
Digital.CSIC. Repositorio Institucional del CSIC
Summary Accurate meiotic chromosome segregation critically depends on the formation of inter-homolog crossovers initiated by double-strand breaks (DSBs). Inaccuracies in this process can drive aneuploidy and developmental defects, but how meiotic cel
Autor:
Jillian L. Youds, Ann M. Rose, Julie S. Martin, Jordan D. Ward, Simon J. Boulton, Barbara J Meyer, Nigel J. O'Neil, Michael J. McIlwraith, David G. Mets, Stephen C. West
Publikováno v:
Science. 327:1254-1258
Managing Crossovers In all sexual eukaryotes a special type of cell division called meiosis produces gametes or spores. For chromosomes to segregate properly to the daughter cells during meiosis, DNA crossovers must occur between every pair of homolo
Publikováno v:
HAND. 5:318-321
Cutaneous fungal infections are a rare but significant complication associated with immunocompromised states. Lesions allowed to progress to disseminated fungemia are associated with a near 80% mortality rate. Treatment guidelines aimed at local cont
Autor:
Federica Marini, Jordan D. Ward, Julie S. Martin, D.M. Muzzini, G. Cassata, Mark I.R. Petalcorin, Enrique Martinez-Perez, Paolo Plevani, Simon J. Boulton
Publikováno v:
Molecular Cell. 37:259-272
Homologous recombination (HR) is essential for repair of meiotic DNA double-strand breaks (DSBs). Although the mechanisms of RAD-51-DNA filament assembly and strand exchange are well characterized, the subsequent steps of HR are less well defined. He
Autor:
Jillian L. Youds, Spencer J. Collis, Michael J. McIlwraith, Simon J. Boulton, Jordan D. Ward, Melissa M. Auclair, Mark I.R. Petalcorin, Nigel J. O'Neil, Heidi A. Tissenbaum, Stephen C. West, Louise J. Barber, Sharon B. Cantor, Ann M. Rose, Julie S. Martin
Publikováno v:
Cell. 135:261-271
SummaryHomologous recombination (HR) is an important conserved process for DNA repair and ensures maintenance of genome integrity. Inappropriate HR causes gross chromosomal rearrangements and tumorigenesis in mammals. In yeast, the Srs2 helicase elim
Autor:
Zebulin Kessler, Judith L. Yanowitz, George Chung, Simon J. Boulton, Ann M. Rose, Julie S. Martin, Luis Sanchez-Pulido, Mark I.R. Petalcorin, Chris P. Ponting
The Caenorhabditis elegans gene rec-1 was the first genetic locus identified in metazoa to affect the distribution of meiotic crossovers along the chromosome. We report that rec-1 encodes a distant paralog of HIM-5, which was discovered by whole-geno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5804c5ff1a89f3b73641c6a79b69e1e
https://europepmc.org/articles/PMC4579353/
https://europepmc.org/articles/PMC4579353/
Publikováno v:
DNA Repair. 5:1398-1406
One of the least well understood DNA repair processes in cells is the repair of DNA interstrand cross-links (ICLs) which present a major obstacle to DNA replication and must be repaired or bypassed to allow fork progression. Fanconi anemia (FA) is an
Autor:
Simon J. Boulton, Julie S. Martin, Mark I.R. Petalcorin, Tatiana García-Muse, Jolanta Polanowska
Publikováno v:
The EMBO Journal. 25:2178-2188
The BRCA1 tumour suppressor and its heterodimeric partner BARD1 constitute an E3-ubiquitin (Ub) ligase and function in DNA repair by unknown mechanisms. We show here that the Caenorhabditis elegans BRCA1/BARD1 (CeBCD) complex possesses an E3-Ub ligas