Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Julie S. Lau"'
Autor:
Shefaa AlAsfoor, Cheryl E. Bernard, Erik Jessen, Vernadette A. Simon, Fariborz Rakhshan, Gianluca Cipriani, Linda C. Hsi, Jack A. Patraw, Kari J. Carothers, Julie S. Lau, Samantha J. McDonough, Surendra Dasari, Gianrico Farrugia, Madhusudan Grover
Publikováno v:
STAR Protocols, Vol 5, Iss 3, Pp 103258- (2024)
Summary: Understanding the diversity of gastrointestinal (GI) immune cells, especially in the muscularis propria, is crucial for understanding their role in the maintenance of enteric neurons and smooth muscle and their contribution to GI motility. H
Externí odkaz:
https://doaj.org/article/c451e2ad6c914ccba7a3b09314efade5
Autor:
Matthew Scotch, Kimberly Lauer, Eric D. Wieben, Yesesri Cherukuri, Julie M. Cunningham, Eric W. Klee, Jonathan J. Harrington, Julie S. Lau, Samantha J. McDonough, Mark Mutawe, John C. O'Horo, Chad E. Rentmeester, Nicole R. Schlicher, Valerie T. White, Susan K. Schneider, Peter T. Vedell, Xiong Wang, Joseph D. Yao, Bobbi S. Pritt, Andrew P. Norgan
Publikováno v:
mSphere, Vol 8, Iss 6 (2023)
ABSTRACTSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has had an unprecedented impact on human health and highlights the need for genomic epidemiology studies to increase our understanding of virus evolution and spread and to inform po
Externí odkaz:
https://doaj.org/article/8777d24714df47e7ade07b71b5f5db3e
Autor:
Debabrata Mukhopadhyay, Suresh T. Chari, Randal J. Kaufman, Gloria M. Petersen, Mark Truty, Santanu Bhattacharya, Julie S. Lau, Thomas C. Smyrk, Shamit K. Dutta, Gunisha Sagar, Naureen Javeed
Supplementary Table 1. Pharmacological Inhibitors of Endocytic Pathways
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c94a7265494754653577ee73cfa65cd
https://doi.org/10.1158/1078-0432.22459881
https://doi.org/10.1158/1078-0432.22459881
Supplementary Fig. 5 from Pancreatic Cancer–Derived Exosomes Cause Paraneoplastic β-cell Dysfunction
Autor:
Debabrata Mukhopadhyay, Suresh T. Chari, Randal J. Kaufman, Gloria M. Petersen, Mark Truty, Santanu Bhattacharya, Julie S. Lau, Thomas C. Smyrk, Shamit K. Dutta, Gunisha Sagar, Naureen Javeed
Supplementary Fig. 5. Adrenomedullin increases reactive oxygen species production. Reactive oxygen/nitrogen species (ROS/RNS) were detected in INS-1 cells pre-treated with either 1 or 20 pM adrenomedullin for 24 hours. The orange filter detects super
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23cc08de48cb896adf287dfbc6bbe60d
https://doi.org/10.1158/1078-0432.22459887
https://doi.org/10.1158/1078-0432.22459887
Supplementary Fig. 4 from Pancreatic Cancer–Derived Exosomes Cause Paraneoplastic β-cell Dysfunction
Autor:
Debabrata Mukhopadhyay, Suresh T. Chari, Randal J. Kaufman, Gloria M. Petersen, Mark Truty, Santanu Bhattacharya, Julie S. Lau, Thomas C. Smyrk, Shamit K. Dutta, Gunisha Sagar, Naureen Javeed
Supplementary Fig. 4. AM and PC-Exosomes modestly upregulate insulin gene expression. All studies were done using INS-1, a rat β-cell line. (A) Relative expression of insulin genes INS1 and INS2 in response to varying concentrations (1, 20, or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1164fd0a39a447912d41a5b97a1ce1be
https://doi.org/10.1158/1078-0432.22459890.v1
https://doi.org/10.1158/1078-0432.22459890.v1
Supplementary Fig. 1 from Pancreatic Cancer–Derived Exosomes Cause Paraneoplastic β-cell Dysfunction
Autor:
Debabrata Mukhopadhyay, Suresh T. Chari, Randal J. Kaufman, Gloria M. Petersen, Mark Truty, Santanu Bhattacharya, Julie S. Lau, Thomas C. Smyrk, Shamit K. Dutta, Gunisha Sagar, Naureen Javeed
Supplementary Fig. 1. NanoTracker results of PC-Exosome isolated from PC patient-derived cell lines and patient plasma. (A-B) PC-Exo isolated from a PC patient-derived cell line show the majority of microparticles are of exosomal size ([A] mode, 105{
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d93e9026b96a8e6a269abf546bfd90f
https://doi.org/10.1158/1078-0432.22459899.v1
https://doi.org/10.1158/1078-0432.22459899.v1
Autor:
Debabrata Mukhopadhyay, Suresh T. Chari, Randal J. Kaufman, Gloria M. Petersen, Mark Truty, Santanu Bhattacharya, Julie S. Lau, Thomas C. Smyrk, Shamit K. Dutta, Gunisha Sagar, Naureen Javeed
Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a69a1cebe5348c66a5011c3a9449ee8
https://doi.org/10.1158/1078-0432.22459884
https://doi.org/10.1158/1078-0432.22459884
Autor:
Debabrata Mukhopadhyay, Suresh T. Chari, Randal J. Kaufman, Gloria M. Petersen, Mark Truty, Santanu Bhattacharya, Julie S. Lau, Thomas C. Smyrk, Shamit K. Dutta, Gunisha Sagar, Naureen Javeed
Purpose: Pancreatic cancer frequently causes diabetes. We recently proposed adrenomedullin as a candidate mediator of pancreatic β-cell dysfunction in pancreatic cancer. How pancreatic cancer–derived adrenomedullin reaches β cells remote from the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a21e1a340d986e4365dc22beadb8d21e
https://doi.org/10.1158/1078-0432.c.6524331.v1
https://doi.org/10.1158/1078-0432.c.6524331.v1
Supplementary Fig. 2 from Pancreatic Cancer–Derived Exosomes Cause Paraneoplastic β-cell Dysfunction
Autor:
Debabrata Mukhopadhyay, Suresh T. Chari, Randal J. Kaufman, Gloria M. Petersen, Mark Truty, Santanu Bhattacharya, Julie S. Lau, Thomas C. Smyrk, Shamit K. Dutta, Gunisha Sagar, Naureen Javeed
Supplementary Fig. 2. PC-derived exosomes from additional PC cell lines and PC patient plasma can decrease insulin secretion. (A-B) PC-Exo isolated from 2 PC patient-derived cell lines decreased insulin secretion in INS-1 cells. (C-D) PC-Exo isolated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::842a1023148375992bd02ae7cfd2d3f7
https://doi.org/10.1158/1078-0432.22459896
https://doi.org/10.1158/1078-0432.22459896
Supplementary Fig. 3 from Pancreatic Cancer–Derived Exosomes Cause Paraneoplastic β-cell Dysfunction
Autor:
Debabrata Mukhopadhyay, Suresh T. Chari, Randal J. Kaufman, Gloria M. Petersen, Mark Truty, Santanu Bhattacharya, Julie S. Lau, Thomas C. Smyrk, Shamit K. Dutta, Gunisha Sagar, Naureen Javeed
Supplementary Fig. 3. Chlorpromazine and Nocodazole do not inhibit exosome internalization. INS-1 cells were treated with varying concentrations of chlorpromazine (A) or Nocodazole (C) for 30 minutes and 10 minutes, respectively. PKH67-dyed PANC-1 ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43d94288559b7a9341569f4b7732aed6
https://doi.org/10.1158/1078-0432.22459893
https://doi.org/10.1158/1078-0432.22459893