Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Julie Rumi"'
Autor:
Gaël Barthet, Tomàs Jordà-Siquier, Julie Rumi-Masante, Fanny Bernadou, Ulrike Müller, Christophe Mulle
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Mutations in presenilin, which cleaves amyloid precursor protein, cause familial Alzheimer’s Disease. Here, the authors show that loss of presenilin leads to loss of synaptotagmin 7, leading to impaired presynaptic release.
Externí odkaz:
https://doaj.org/article/9141dd69adf04d1c8a0ace613a53f522
Autor:
Céline Boileau, Severine Deforges, Angélique Peret, Didier Scavarda, Fabrice Bartolomei, April Giles, Nicolas Partouche, Justine Gautron, Julio Viotti, Haley Janowitz, Guillaume Penchet, Cécile Marchal, Stanislas Lagarde, Agnès Trebuchon, Nathalie Villeneuve, Julie Rumi, Thomas Marissal, Roustem Khazipov, Ilgam Khalilov, Fanny Martineau, Marine Maréchal, Anne Lepine, Mathieu Milh, Dominique Figarella-Branger, Etienne Dougy, Soutsakhone Tong, Romain Appay, Stéphane Baudouin, Andrew Mercer, Jared B. Smith, Olivier Danos, Richard Porter, Christophe Mulle, Valérie Crépel
ObjectiveTemporal lobe epilepsy (TLE) is characterized by recurrent seizures generated in the limbic system, particularly in the hippocampus. In TLE, recurrent mossy fiber sprouting from dentate gyrus granule cells (DGCs) creates an aberrant epilepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b20ee85ea08d21a538c10980cc0764cf
https://doi.org/10.1101/2023.04.13.536748
https://doi.org/10.1101/2023.04.13.536748
Autor:
Tori B. Dunlap, Terrence E. Lester, Emily Holbrook, Trevor P. Creamer, Christopher L. Colbert, Julie Rumi-Masante, Erik C. Cook, Hou Fu Guo, Craig W. Vander Kooi
Publikováno v:
Biochemistry. 53:5779-5790
Calcineurin is an essential serine/threonine phosphatase that plays vital roles in neuronal development and function, heart growth, and immune system activation. Calcineurin is unique in that it is the only phosphatase known to be activated by calmod
Autor:
Terrence E. Lester, Erik C. Cook, Julie Rumi-Masante, Trevor P. Creamer, Tori B. Dunlap, Hannah G. Arvin
Publikováno v:
Biochemistry. 52:8643-8651
Calcineurin (CaN) is a calmodulin-activated, serine/threonine phosphatase that is necessary for cardiac, vasculature, and nervous system development, as well as learning and memory, skeletal muscle growth, and immune system activation. CaN is activat
Autor:
Julie Rumi, Juliette Bitard, Cyril Masante, Thérèse Astier-Gin, Kathleen Mahias, Michel Ventura, Gaëlle Chognard, Estelle Dumas
Publikováno v:
Antiviral Research. 87:9-15
The current treatments used against RNA viruses have a limited efficacy and are often hampered by the induction of side-effects. The specific delivery of antiviral proteins in infected cells should increase their efficiency and reduce their impact on
Autor:
Todd D. Williams, Trevor P. Creamer, A. Keith Dunker, Terrence E. Lester, Farai I. Rusinga, Julie Rumi-Masante, Tori B. Dunlap, David D. Weis
The highly conserved phosphatase calcineurin plays vital roles in numerous processes including T-cell activation, development and function of the central nervous system, and cardiac growth. It is activated by the calcium sensor calmodulin. Calmodulin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::132eb4ded2d043abe203a83254beb686
https://europepmc.org/articles/PMC3258384/
https://europepmc.org/articles/PMC3258384/
Autor:
Tori M. Dunlap, Trevor P. Creamer, Farai I. Rusinga, Terrence E. Lester, David D. Weis, A. Keith Dunker, Julie Rumi-Masante
Publikováno v:
Biophysical Journal. 100(3)
Calcineurin (CaN) is a highly-conserved, ubiquitous Ser/Thr phosphatase that plays vital roles in memory development and retention, cardiac growth, and immune system activation. Alterations in the regulation of CaN contributes to disorders such as Al
Autor:
Thérèse Astier-Gin, Julie Rumi, Laura Tarrago-Litvak, Michel Ventura, Marie-Line Andreola, Christian Cazenave, Pantxika Bellecave, Ophélie Cosnefroy, Cathy Staedel
Publikováno v:
Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2008, 52 (6), pp.2097-110. ⟨10.1128/AAC.01227-07⟩
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2008, 52 (6), pp.2097-110. ⟨10.1128/AAC.01227-07⟩
We describe here the further characterization of two DNA aptamers that specifically bind to hepatitis C virus (HCV) RNA polymerase (NS5B) and inhibit its polymerase activity in vitro. Although they were obtained from the same selection procedure and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d07c73fa02d7eb1ea5c11151c5d9396
https://hal.archives-ouvertes.fr/hal-00319130
https://hal.archives-ouvertes.fr/hal-00319130
Autor:
Cathy Staedel, Aude Pflieger, Sandrine Chabas, Julie Rumi, Jean-Jacques Toulmé, Sandrine Reigadas, Czeslaw Wychowski, Michel Ventura, Loic Jaffrelo
Publikováno v:
Nucleic Acids Research
We developed a functional selection system based on randomized genetic elements (GE) to identify potential regulators of hepatitis C virus (HCV) RNA translation, a process initiated by an internal ribosomal entry site (IRES). A retroviral HCV GE libr