Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Julie R. Friend"'
Publikováno v:
Cell Transplantation, Vol 8 (1999)
Primary rat hepatocytes can self-assemble to form multicellular spheroids when plated onto Primaria petri dishes. Spheroids have been observed to exhibit enhanced liver-specific functions and differentiated ultrastructure compared to monolayer cultur
Externí odkaz:
https://doaj.org/article/5bd98762d82e43459274a7ea54e808e0
Autor:
Julie R. Friend, Florence J. Wu, Chang-Chun Hsiao, Wei Shou Hu, Linda K. Hansen, Gary A. Bridge, Rory P. Remmel, Frank B. Cerra
Publikováno v:
Tissue Engineering. 4:65-74
Hepatocytes can self-assemble into spheroids, which express enhanced differentiated function and may provide an important tool in tissue engineering. This study examines cell junction components as hepatocytes form either monolayer or spheroid, and c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75b9f85dac89a7fe5428ae08d6c7b9d2
https://doi.org/10.1089/ten.1998.4.65
https://doi.org/10.1089/ten.1998.4.65
Autor:
Frank B. Cerra, Madhusudan V. Peshwa, Timothy D. Sielaff, Florence J. Wu, Julie R. Friend, Wei Shou Hu, Scott L. Nyberg, Arye Lazar, Rory P. Remmel
Publikováno v:
Cytotechnology. 23:29-38
Liver failure is a major cause of mortality. A bioartificial liver (BAL) employing isolated hepatocytes can potentially provide temporary support for liver failure patients. We have developed a bioartificial liver by entrapping hepatocytes in collage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7045bc7dcf3654a1ac109d9ca7eb239a
https://doi.org/10.1023/a:1007906512616
https://doi.org/10.1023/a:1007906512616
Autor:
Rory P. Remmel, Florence J. Wu, Arye Lazar, Henry J. Mann, Julie R. Friend, Wei Shou Hu, Frank B. Cerra
Publikováno v:
Biotechnology and Bioengineering. 52:34-44
A xenogeneic hollow fiber bioreactor utilizing collagen-entrapped dispersed hepatocytes has been developed as an extracorporeal bioartificial liver (BAL) for potential treatment of acute human fulminant hepatitis. Prolonged viability, enhanced liver-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3fcae53394a54d19f4b6c0aa2534ece
https://doi.org/10.1002/(sici)1097-0290(19961005)52:1<34::aid-bit4>3.0.co
https://doi.org/10.1002/(sici)1097-0290(19961005)52:1<34::aid-bit4>3.0.co
Autor:
Frank B. Cerra, Florence J. Wu, Wen Je Ko, Julie R. Friend, Chang-Chun Hsiao, Wei Shou Hu, Michael J. Zilliox
Publikováno v:
Biotechnology and Bioengineering. 50:404-415
Freshly harvested primary rat hepatocytes cultivated as multicellular aggregates, or spheroids, have been observed to exhibit enhanced liver-specific function and differentiated morphology compared to cells cultured as monolayers. An efficient method
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41105eb19127bcef0e66911085d1f09d
https://doi.org/10.1002/(sici)1097-0290(19960520)50:4<404::aid-bit7>3.0.co
https://doi.org/10.1002/(sici)1097-0290(19960520)50:4<404::aid-bit7>3.0.co
Several investigators have demonstrated that freshly harvested hepatocytes self-assemble into three-dimensional, compacted, freely suspended aggregates known as spheroids (1-3). These aggregates have smooth, undulating surfaces and average approx 120
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94e131c1170ee5e59c0d1c96d0b5a693
https://doi.org/10.1385/0-89603-516-6:245
https://doi.org/10.1385/0-89603-516-6:245
Publikováno v:
Experimental cell research. 274(1)
Primary hepatocytes self-assemble into spheroids that possess tight junctions and microvilli-lined channels. We hypothesized that polarity develops gradually and that the channels structurally and functionally resemble bile canaliculi. Immunofluoresc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f49942fd60ca274108dbbcd05630ed0
https://pubmed.ncbi.nlm.nih.gov/11855857
https://pubmed.ncbi.nlm.nih.gov/11855857
Publikováno v:
Animal Cell Technology: Basic & Applied Aspects ISBN: 9789048159345
Rat hepatocytes, when cultured on moderately-adhesive substrates or in suspension, self-assemble into three dimensional, compacted, spherical aggregates called spheroids [1, 2]. In addition to maintaining higher liver-specific functions than monolaye
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b3a824e57053c7b5ccb1be11909f147
https://doi.org/10.1007/978-94-017-0728-2_43
https://doi.org/10.1007/978-94-017-0728-2_43
Publikováno v:
Cell Transplantation, Vol 8 (1999)
Primary rat hepatocytes can self-assemble to form multicellular spheroids when plated onto Primaria petri dishes. Spheroids have been observed to exhibit enhanced liver-specific functions and differentiated ultrastructure compared to monolayer cultur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76aeaa59f8ccb5a0f1eff7fabfa1777d
https://pubmed.ncbi.nlm.nih.gov/10442736
https://pubmed.ncbi.nlm.nih.gov/10442736
Publikováno v:
Tissue engineering. 5(3)
Primary rat hepatocytes can self-assemble to form multicellular spheroids when plated onto Primaria petri dishes or suspended in stirred vessels. These spheroids exhibit prolonged viability, enhanced liver-specific functions and differentiated ultras
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be8437ff6c0be30e2e3cac89a8425b1b
https://pubmed.ncbi.nlm.nih.gov/10434069
https://pubmed.ncbi.nlm.nih.gov/10434069