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pro vyhledávání: '"Julie R. Escamilla-Powers"'
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 2, Iss C (2013)
Optimization of small interfering RNAs (siRNAs) is important in RNA interference (RNAi)-based therapeutic development. Some specific chemical modifications can control which siRNA strand is selected by the RNA-induced silencing complex (RISC) for gen
Externí odkaz:
https://doaj.org/article/9fffe1b46cce41db8118cdfea9f1e9bf
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 2, Iss C (2013)
Molecular Therapy. Nucleic Acids
Molecular Therapy. Nucleic Acids
Optimization of small interfering RNAs (siRNAs) is important in RNA interference (RNAi)-based therapeutic development. Some specific chemical modifications can control which siRNA strand is selected by the RNA-induced silencing complex (RISC) for gen
Autor:
Joel Jessee, Julie R. Escamilla-Powers, Brea Midthune, Anton P. McCaffrey, Alexandre Lebedev, Dongwon Shin, Richard I. Hogrefe, Hiroko Yokoe, Krist T. Azizian
Publikováno v:
Molecular Therapy. 23:S259
Recently, there has been significant interest in the use of messenger RNA (mRNA) based expression systems for gene therapy applications. Several groups have shown that mRNA is an attractive vehicle for therapeutic gene expression in mammals (Kormann