Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Julie R. Field"'
Autor:
Robert Michael Cronin, Julie R Field, Yuki eBradford, Christian M Shaffer, Robert J Carroll, Jonathan D Mosley, Lisa eBastarache, Todd L Edwards, Scott J Hebbring, Simon eLin, Lucia A Hindorff, Paul K Crane, Sarah ePendergrass, Marylyn D Ritchie, Dana C Crawford, Jyotishman ePathak, Suzette eBielinski, David S Carrell, David R Crosslin, David H Ledbetter, David J Carey, Gerard eTromp, Marc S Williams, Eric B Larson, Gail P Jarvik, Peggy L Peissig, Murray H Brilliant, Catherine Anne McCarty, Christopher G Chute, Iftikhar J Kullo, Erwin eBottinger, Rex eChisholm, Maureen E Smith, Dan M Roden, Joshua C Denny
Publikováno v:
Frontiers in Genetics, Vol 5 (2014)
Phenome-wide association studies (PheWAS) have demonstrated utility in validating genetic associations derived from traditional genetic studies as well as identifying novel genetic associations. Here we used an electronic health record (EHR)-based Ph
Externí odkaz:
https://doaj.org/article/0ab6e1db8b1b479ea15406e8958cb57a
Autor:
Liewei Wang, Jill M. Pulley, Mark J. Ratain, Julie A. Johnson, Wolfgang Sadee, Rhonda M. Cooper-DeHoff, Teri E. Klein, Ruth E. Pakyz, Julie R. Field, Alan R. Shuldiner, Russ B. Altman, Mary V. Relling, Peter H. O'Donnell, Josh F. Peterson, Samuel K. Handelman, Peter J. Embi, Jasmine A. Luzum, Larisa H. Cavallari, Naveen L. Pereira, Cyrine E. Haidar, Kathleen Palmer, Michelle Whirl-Carrillo, Dan M. Roden, Kristin Weitzel, Robert R. Freimuth, Jonathan S. Schildcrout, Marc Beller, Amanda R. Elsey, Richard M. Weinshilboum
Publikováno v:
Clinical Pharmacology & Therapeutics. 102:502-510
Numerous pharmacogenetic clinical guidelines and recommendations have been published, but barriers have hindered the clinical implementation of pharmacogenetics. The Translational Pharmacogenetics Program (TPP) of the National Institutes of Health (N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58319e545ef623329af5cbe37b00ba2f
https://doi.org/10.1002/cpt.630
https://doi.org/10.1002/cpt.630
Autor:
William M. Gregg, Joshua C. Denny, Melissa A. Basford, Frank E. Harrell, Jonathan S. Schildcrout, Ioana Danciu, James D. Cowan, Erica Bowton, Josh F. Peterson, Julie R. Field, Yaping Shi, Jill M. Pulley, Dan M. Roden
Publikováno v:
Journal of Clinical Epidemiology. 72:107-115
Objectives We describe the development, implementation, and evaluation of a model to pre-emptively select patients for genotyping based on medication exposure risk. Study Design and Setting Using deidentified electronic health records, we derived a p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25070514e511dc26885dcabcb5810516
https://doi.org/10.1016/j.jclinepi.2015.08.028
https://doi.org/10.1016/j.jclinepi.2015.08.028
Autor:
John A. McPherson, Kevin B. Johnson, Ioana Danciu, Jonathan S. Schildcrout, Daniel C. Johnson, Josh C. Denny, Dan M. Roden, Michael Laposata, Yaping Shi, Kim M. Unertl, Jill M. Pulley, John H. Cleator, Josh F. Peterson, Julie R. Field
Publikováno v:
Clinical Pharmacology & Therapeutics. 100:67-74
Physician responses to genomic information are vital to the success of precision medicine initiatives. We prospectively studied a pharmacogenomics implementation program for the propensity of clinicians to select antiplatelet therapy based on CYP2C19
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4df63eb7f499d0796548075cdf20598
https://doi.org/10.1002/cpt.331
https://doi.org/10.1002/cpt.331
Autor:
S L Van Driest, Joshua C. Denny, Ellen Wright Clayton, Jonathan S. Schildcrout, Yaping Shi, Julie R. Field, Josh F. Peterson, Jill M. Pulley, Dan M. Roden, Michael Laposata, Tracy L. McGregor, I. M. Lubin
Publikováno v:
The pharmacogenomics journal
Clinician attitudes toward multiplexed genomic testing may be vital to the success of translational programs. We surveyed clinicians at an academic medical center about their views on a large pharmacogenomics implementation, the PREDICT (Pharmacogeno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67fb0d8913dcfe17e4b4ce975e27449a
http://europepmc.org/articles/PMC4751074
http://europepmc.org/articles/PMC4751074
Publikováno v:
Personalized Medicine. 12:339-347
Aim: To describe the knowledge and attitudes of clinicians participating in a large pharmacogenomics implementation program. Materials & methods: Semi-structured interviews with 15 physicians and nurse practitioners were conducted. Results: Three cat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee3a89e16f8885f5a7853cbec37bc96f
https://doi.org/10.2217/pme.15.10
https://doi.org/10.2217/pme.15.10
Autor:
Zixiu Xiang, Corey R. Hopkins, Craig W. Lindsley, Michael R. Wood, Emily Days, Sean R. Bollinger, Karen J. Gregory, Francine Acher, L. Michelle Lewis, Darren W. Engers, P. Jeffrey Conn, Julie R. Field, Colleen M. Niswender, Margrith E. Mattmann, Bruce J. Melancon, C. David Weaver, Adam G. Walker, Rocio Zamorano, Rebecca Klar, Miguel A. Hurtado, Nidhi Jalan-Sakrikar, Thomas J. Utley, Delphine Rigault
Publikováno v:
ACS Chemical Neuroscience
Metabotropic glutamate receptor 7 (mGlu7) is a member of the group III mGlu receptors (mGlus), encompassed by mGlu4, mGlu6, mGlu7, and mGlu8. mGlu7 is highly expressed in the presynaptic active zones of both excitatory and inhibitory synapses, and ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53054405fa5493f60e9af66a15e0439b
https://doi.org/10.1021/cn500153z
https://doi.org/10.1021/cn500153z
Autor:
Barbara A. Koenig, Carol R. Horowitz, Catherine A. McCarty, Stephanie M. Fullerton, Saskia C. Sanderson, Luke V. Rasmussen, Susan Brown Trinidad, Marc S. Williams, Ellen Wright Clayton, Jennifer B. McCormick, William A. Faucett, Kadija Ferryman, Julie R. Field, James D. Ralston, Andrea L. Hartzler, Murray H. Brilliant, Maureen E. Smith, Erica Bowton
Publikováno v:
Genetics in Medicine. 15:792-801
Integrating genomic information into clinical care and the electronic health record can facilitate personalized medicine through genetically guided clinical decision support. Stakeholder involvement is critical to the success of these implementation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6f7a5e0c04c7e43495208b71718e72b
https://doi.org/10.1038/gim.2013.127
https://doi.org/10.1038/gim.2013.127
Autor:
Mia A. Levy, Carol R. Horowitz, Diane Hauser, David A. Flockhart, Kristin Weitzel, Julie A. Johnson, Madeline Alexander, David J. Carey, Ebony B. Madden, Barbara A. Bernhardt, Phillip A. Levin, Erwin P. Bottinger, Joshua C. Denny, Lori A. Orlando, Toni I. Pollin, Alan R. Shuldiner, Kenneth D. Levy, Teri A. Manolio, R. Ryanne Wu, Julie R. Field, Heather Junkins, Larisa H. Cavallari, Neil Calman, Stephen E. Kimmel, Geoffrey S. Ginsburg, Jacqueline A. Odgis, Reed E. Pyeritz, Paul R. Dexter
Publikováno v:
BMC Medical Genomics
Patients, clinicians, researchers and payers are seeking to understand the value of using genomic information (as reflected by genotyping, sequencing, family history or other data) to inform clinical decision-making. However, challenges exist to wide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b5e1231f54a6559363c9e350ef3526d
https://doi.org/10.1186/s12920-015-0162-5
https://doi.org/10.1186/s12920-015-0162-5
Publikováno v:
Trends in Molecular Medicine. 17:689-698
Although early clinical observations implicated dopamine dysfunction in the neuropathology of schizophrenia, accumulating evidence suggests that multiple neurotransmitter pathways are dysregulated. The psychotomimetic actions of NMDA receptor antagon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1de0d03a20975c8b729bcba5a6dbb167
https://doi.org/10.1016/j.molmed.2011.08.004
https://doi.org/10.1016/j.molmed.2011.08.004