Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Julie Quoyer"'
Autor:
Stéphane Dalle, Elodie M. Varin, Christine Longuet, Gyslaine Bertrand, Safia Costes, Joël Bockaert, Nathalie Linck, Julie Quoyer, Christophe Broca
Publikováno v:
Journal of Biological Chemistry. 285:1989-2002
Strategies based on activating GLP-1 receptor (GLP-1R) are intensively developed for the treatment of type 2 diabetes. The exhaustive knowledge of the signaling pathways linked to activated GLP-1R within the beta-cells is of major importance. In beta
Publikováno v:
Recent Patents on Endocrine, Metabolic & Immune Drug Discovery. 1:180-192
Type 2 diabetes (T2D) is a heterogeneous disorder that is characterized by chronic hyperglycemia and its prevalence reaches epidemic proportions worldwide. T2D is characterized by a progressive loss of the first phase of insulin secretion in early st
Autor:
Reynold A. Panettieri, Michel Bouvier, Yang Du, Richard Carr, Jeffrey L. Benovic, Jay M. Janz, Brian K. Kobilka, Julie Quoyer
The β2-adrenergic receptor (β2AR) is a prototypical G protein-coupled receptor that mediates many hormonal responses, including cardiovascular and pulmonary function. β-Agonists used to combat hypercontractility in airway smooth muscle stimulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f69a50fbff14f3216ad84aba971a8d2
https://europepmc.org/articles/PMC4276837/
https://europepmc.org/articles/PMC4276837/
Autor:
Julie Quoyer, Arhamatoulaye Maiga, Yann Percherancier, Michel Bouvier, Nikolaus Heveker, Viktorya Lukashova, Laurent Prézeau, Jean-Philippe Pin, Sylvain Armando
Publikováno v:
FASEB Journal
FASEB Journal, Federation of American Society of Experimental Biology, 2014, 28 (10), pp.4509--23. ⟨10.1096/fj.13-242446⟩
FASEB Journal, Federation of American Society of Experimental Biology, 2014, 28 (10), pp.4509--23. ⟨10.1096/fj.13-242446⟩
International audience; G-protein-coupled receptors have been shown to assemble at least as dimers early in the biosynthetic path, but some evidence suggests that they can also form larger oligomeric complexes. Using the human chemokine receptors CXC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3f12935e16beec9236378f950a688c5
https://hal.umontpellier.fr/hal-01950128
https://hal.umontpellier.fr/hal-01950128
Autor:
Kenneth E. Carlson, Jay M. Janz, Sylvain Armando, Viktoria Lukashova, Michel Bouvier, Julie Quoyer, Yong Ren, Jiansong Luo, Jeffrey L. Benovic, Stephen W. Hunt
Short lipidated peptide sequences derived from various intracellular loop regions of G protein-coupled receptors (GPCRs) are named pepducins and act as allosteric modulators of a number of GPCRs. Recently, a pepducin selectively targeting the C-X-C c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::208ecb7b980de57e1f930cd2fc88e52d
https://europepmc.org/articles/PMC3876208/
https://europepmc.org/articles/PMC3876208/
Publikováno v:
Current molecular pharmacology. 4(3)
The preservation of a functional pancreatic β-cell mass has become a major point of research in type 2 diabetes (T2D) and the future therapies of T2D notably aim at protecting the β-cell from dysfunction and apoptotic death. β-cell proliferation,
Autor:
Annie Varrault, Christophe Broca, Stéphane Dalle, Julie Quoyer, Nathalie Linck, Joël Bockaert, Pierre-Marie Deffayet, Safia Costes, Gyslaine Bertrand
Publikováno v:
The Journal of biological chemistry. 284(7)
In pancreatic beta-cells, the pituitary adenylate cyclase-activating polypeptide (PACAP) exerts a potent insulin secretory effect via PAC(1) and VPAC receptors (Rs) through the Galpha(s)/cAMP/protein kinase A pathway. Here, we investigated the mechan
Autor:
Béatrice Duthey, Jean-Philippe Pin, Claire Vol, Laurent Prézeau, Virginie Binet, Jennifer Lecaillon, Gilles Labesse, Julie Quoyer
Publikováno v:
Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2007, 282 (16), pp.12154-63. ⟨10.1074/jbc.M611071200⟩
Journal of Biological Chemistry, 2007, 282 (16), pp.12154-63. ⟨10.1074/jbc.M611071200⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2007, 282 (16), pp.12154-63. ⟨10.1074/jbc.M611071200⟩
Journal of Biological Chemistry, 2007, 282 (16), pp.12154-63. ⟨10.1074/jbc.M611071200⟩
International audience; G protein-coupled receptors (GPCRs) are key players in cell communication. Several classes of such receptors have been identified. Although all GPCRs possess a heptahelical domain directly activating G proteins, important stru
Autor:
Armando, Sylvain, Quoyer, Julie, Lukashova, Viktorya, Maiga, Arhamatoulaye, Percherancier, Yann, Heveker, Nikolaus, Pin, Jean-Philippe, Prézeau, Laurent, Bouvier, Michel
Publikováno v:
FASEB Journal; Oct2014, Vol. 28 Issue 10, p4509-4523, 15p