Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Julie Pannequin"'
Autor:
Gabriel Therizols, Zeina Bash-Imam, Baptiste Panthu, Christelle Machon, Anne Vincent, Julie Ripoll, Sophie Nait-Slimane, Mounira Chalabi-Dchar, Angéline Gaucherot, Maxime Garcia, Florian Laforêts, Virginie Marcel, Jihane Boubaker-Vitre, Marie-Ambre Monet, Céline Bouclier, Christophe Vanbelle, Guillaume Souahlia, Elise Berthel, Marie Alexandra Albaret, Hichem C. Mertani, Michel Prudhomme, Martin Bertrand, Alexandre David, Jean-Christophe Saurin, Philippe Bouvet, Eric Rivals, Théophile Ohlmann, Jérôme Guitton, Nicole Dalla Venezia, Julie Pannequin, Frédéric Catez, Jean-Jacques Diaz
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Different mechanisms have been reported to explain resistance to chemotherapy in cancer. Here, the authors show that the chemotherapeutic drug 5-fluorouracil alters the function of ribosomes to promote pro-survival gene translation leading to chemoth
Externí odkaz:
https://doaj.org/article/8864c0c71ca844a0835d6a8c1a22dd59
Autor:
Louciné Mitoyan, Véronique Chevrier, Hector Hernandez-Vargas, Alexane Ollivier, Zeinab Homayed, Julie Pannequin, Flora Poizat, Cécile De Biasi-Cador, Emmanuelle Charafe-Jauffret, Christophe Ginestier, Géraldine Guasch
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Transition zones connect distinct epithelia, contain cells expressing stem cell markers, and contribute to cancer development. Here, the authors examine the mouse anorectal junction, identifying a population of Krt17-positive basal cells that contrib
Externí odkaz:
https://doaj.org/article/296e414aa37a402286028e30347ff680
Paracrine signalling between intestinal epithelial and tumour cells induces a regenerative programme
Autor:
Guillaume Jacquemin, Annabelle Wurmser, Mathilde Huyghe, Wenjie Sun, Zeinab Homayed, Candice Merle, Meghan Perkins, Fairouz Qasrawi, Sophie Richon, Florent Dingli, Guillaume Arras, Damarys Loew, Danijela Vignjevic, Julie Pannequin, Silvia Fre
Publikováno v:
eLife, Vol 11 (2022)
Tumours are complex ecosystems composed of different types of cells that communicate and influence each other. While the critical role of stromal cells in affecting tumour growth is well established, the impact of mutant cancer cells on healthy surro
Externí odkaz:
https://doaj.org/article/e9e065c131b145b4a69e685a41442aaa
Autor:
Sébastien Relier, Julie Ripoll, Hélène Guillorit, Amandine Amalric, Cyrinne Achour, Florence Boissière, Jérôme Vialaret, Aurore Attina, Françoise Debart, Armelle Choquet, Françoise Macari, Virginie Marchand, Yuri Motorin, Emmanuelle Samalin, Jean-Jacques Vasseur, Julie Pannequin, Francesca Aguilo, Evelyne Lopez-Crapez, Christophe Hirtz, Eric Rivals, Amandine Bastide, Alexandre David
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
The demethylase FTO was shown to remove on N6-methyladenosine (m6A) and N6, 2’-O-dimethyladenosine (m6Am) modifications on RNAs. Here the authors show that FTO impedes cancer stem cell-like abilities in colorectal cancer cells through its m6Am deme
Externí odkaz:
https://doaj.org/article/9446244d632a4b05a389d98461a70dd7
Autor:
Céline Hervieu, Mireille Verdier, Elodie Barthout, Gaëlle Bégaud, Niki Christou, Magali Sage, Julie Pannequin, Serge Battu, Muriel Mathonnet
Publikováno v:
Cells, Vol 11, Iss 15, p 2264 (2022)
Cancer stem cells play a crucial role in tumor initiation, metastasis, and resistance to treatment. Cellular heterogeneity and plasticity complicate the isolation of cancer stem cells. The impact of intra-tumor cellular heterogeneity using a label-fr
Externí odkaz:
https://doaj.org/article/04bb957d97ab4d3b96028f90f2d27d44
Autor:
Guillaume Belthier, Zeinab Homayed, Fanny Grillet, Christophe Duperray, Julie Vendrell, Ilona Krol, Sophie Bravo, Jean-Christophe Boyer, Olivia Villeronce, Jihane Vitre-Boubaker, Diana Heaug-Wane, Françoise Macari-Fine, Jai Smith, Matthieu Merlot, Gérald Lossaint, Thibault Mazard, Fabienne Portales, Jérôme Solassol, Marc Ychou, Nicola Aceto, Emilie Mamessier, François Bertucci, Jean Marc Pascussi, Emmanuelle Samalin, Frédéric Hollande, Julie Pannequin
Publikováno v:
Cancers, Vol 13, Iss 19, p 4966 (2021)
Circulating tumor cells (CTCs) are promising diagnostic and prognostic tools for clinical use. In several cancers, including colorectal and breast, the CTC load has been associated with a therapeutic response as well as progression-free and overall s
Externí odkaz:
https://doaj.org/article/2879e232f7414747a84f5af15b30ff47
Autor:
Maya Jeitany, Cédric Leroy, Priscillia Tosti, Marie Lafitte, Jordy Le Guet, Valérie Simon, Debora Bonenfant, Bruno Robert, Fanny Grillet, Caroline Mollevi, Safia El Messaoudi, Amaëlle Otandault, Lucile Canterel‐Thouennon, Muriel Busson, Alain R Thierry, Pierre Martineau, Julie Pannequin, Serge Roche, Audrey Sirvent
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 4, Pp n/a-n/a (2018)
Abstract The clinical management of metastatic colorectal cancer (mCRC) faces major challenges. Here, we show that nilotinib, a clinically approved drug for chronic myeloid leukaemia, strongly inhibits human CRC cell invasion in vitro and reduces the
Externí odkaz:
https://doaj.org/article/c79f020dc047450c9db38f20c405e854
Autor:
Sebastian Müller, Antoine Versini, Fabien Sindikubwabo, Guillaume Belthier, Supaporn Niyomchon, Julie Pannequin, Laurence Grimaud, Tatiana Cañeque, Raphaël Rodriguez
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0206764 (2018)
The clinically approved drug metformin has been shown to selectively kill persister cancer cells through mechanisms that are not fully understood. To provide further mechanistic insights, we developed a drug surrogate that phenocopies metformin and c
Externí odkaz:
https://doaj.org/article/47bef2b6b7f24f2197700a699b68b920
Autor:
Sebastian Müller, Antoine Versini, Fabien Sindikubwabo, Guillaume Belthier, Supaporn Niyomchon, Julie Pannequin, Laurence Grimaud, Tatiana Cañeque, Raphaël Rodriguez
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0208213 (2018)
[This corrects the article DOI: 10.1371/journal.pone.0206764.].
Externí odkaz:
https://doaj.org/article/c2a410ad3266423b950ada03666940d9
Autor:
Nikola Arsic, Gilles Gadea, E. Louise Lagerqvist, Muriel Busson, Nathalie Cahuzac, Carsten Brock, Frederic Hollande, Veronique Gire, Julie Pannequin, Pierre Roux
Publikováno v:
Stem Cell Reports, Vol 4, Iss 4, Pp 531-540 (2015)
Cancer stem cells (CSC) are responsible for cancer chemoresistance and metastasis formation. Here we report that Δ133p53β, a TP53 splice variant, enhanced cancer cell stemness in MCF-7 breast cancer cells, while its depletion reduced it. Δ133p53β
Externí odkaz:
https://doaj.org/article/0aaaf0b4f7714d188e636c971deda2ea