Výsledky vyhledávání - "Julie P. Saiki"

Treatment-refractory ulcerative colitis responsive to indigo naturalis

Autor: Julie P Saiki, Johan OL Andreasson, Kevin V Grimes, Lyn R Frumkin, Elvi Sanjines, Matthew G Davidson, KT Park, Berkeley Limketkai

Publikováno v: BMJ open gastroenterology, vol 8, iss 1
BMJ Open Gastroenterology

BackgroundIndigo naturalis (IN) is an herbal medicine that has been used for ulcerative colitis with an unclear mechanism of action. Indigo and indirubin, its main constituents, are ligands of the aryl hydrocarbon receptor (AhR). We assessed the safe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7753654a8b57f273e181fa1f207ce22
https://escholarship.org/uc/item/86h208qv

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Aldehyde dehydrogenase 3A1 activation prevents radiation-induced xerostomia by protecting salivary stem cells from toxic aldehydes

Autor: Hongbin Cao, Aaron J Mattingly, Joshua Bloomstein, Hyun Shin Park, Eric T. Kool, Sarah M. Knox, Matthew C. Stevens, Dadi Jiang, Che-Hong Chen, Amanda Simmons, Julie P. Saiki, Lauren D. Van Wassenhove, Vignesh Viswanathan, Davud Sirjani, Daria Mochly-Rosen, Dhanya Nambiar, Rie von Eyben, Quynh-Thu Le

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, vol 115, iss 24

Xerostomia (dry mouth) is the most common side effect of radiation therapy in patients with head and neck cancer and causes difficulty speaking and swallowing. Since aldehyde dehydrogenase 3A1 (ALDH3A1) is highly expressed in mouse salivary stem/prog

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::719790fbc68ee74f46674dc57cbee166
https://pubmed.ncbi.nlm.nih.gov/29794221

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