Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Julie Nardone"'
Autor:
Thomas Clarke, Pan Du, Satyendra Kumar, Shinji L. Okitsu, Mark Schuette, Qi An, Jinyang Zhang, Evgeni Tzvetkov, Mark A. Jensen, Timothy B. Niewold, Elise M. N. Ferre, Julie Nardone, Michail S. Lionakis, Jaromir Vlach, Julie DeMartino, Andrew T. Bender
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Autoimmune diseases vary in the magnitude and diversity of autoantibody profiles, and these differences may be a consequence of different types of breaks in tolerance. Here, we compared the disparate autoimmune diseases autoimmune polyendocrinopathy
Externí odkaz:
https://doaj.org/article/e823a778e94642ba916ed495ae37f622
Autor:
Ting-lei Gu, Julie Nardone, Yi Wang, Marc Loriaux, Judit Villén, Sean Beausoleil, Meghan Tucker, Jon Kornhauser, Jianmin Ren, Joan MacNeill, Steven P Gygi, Brian J Druker, Michael C Heinrich, John Rush, Roberto D Polakiewicz
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e19169 (2011)
Activating mutations of FMS-like tyrosine kinase-3 (FLT3) are found in approximately 30% of patients with acute myeloid leukemia (AML). FLT3 is therefore an attractive drug target. However, the molecular mechanisms by which FLT3 mutations lead to cel
Externí odkaz:
https://doaj.org/article/1023d0cf89bb45dc84d23254aa8bce3c
Autor:
Ting-Lei Gu, Xiaxing Deng, Feizhou Huang, Meghan Tucker, Katherine Crosby, Victoria Rimkunas, Yi Wang, Gang Deng, Lei Zhu, Zhiping Tan, Yerong Hu, Chunlin Wu, Julie Nardone, Joan MacNeill, Jianmin Ren, Cynthia Reeves, Gregory Innocenti, Brett Norris, Jin Yuan, Jian Yu, Herbert Haack, Baiyong Shen, Chenghong Peng, Hongwei Li, Xinmin Zhou, Xunyang Liu, John Rush, Michael J Comb
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e15640 (2011)
Cholangiocarcinoma, also known as bile duct cancer, is the second most common primary hepatic carcinoma with a median survival of less than 2 years. The molecular mechanisms underlying the development of this disease are not clear. To survey activate
Externí odkaz:
https://doaj.org/article/4891caa438b14afea1b111e11dc6ac77
Autor:
Fred Saad, Philip Kantoff, Jonathan I. Epstein, Mathieu Latour, Cristina Magi-Galluzzi, Eric A. Klein, Massimo Loda, James Dunyak, Julie Nardone, Eldar Giladi, Hua Chang, Alex Kaprelyants, Aeron Hurley, Christina Ernst, Louis Coupal, Teresa Capela, Sibgat Choudhury, Clayton Small, Thomas P. Nifong, Mathew Putzi, Michail Shipitsin, David L. Rimm, David M. Berman, Peter Blume-Jensen
Purpose: Prostate cancer aggressiveness and appropriate therapy are routinely determined following biopsy sampling. Current clinical and pathologic parameters are insufficient for accurate risk prediction leading primarily to overtreatment and also m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8a1d5ad71950008144484ceac754a37
https://doi.org/10.1158/1078-0432.c.6524298
https://doi.org/10.1158/1078-0432.c.6524298
Autor:
Fred Saad, Philip Kantoff, Jonathan I. Epstein, Mathieu Latour, Cristina Magi-Galluzzi, Eric A. Klein, Massimo Loda, James Dunyak, Julie Nardone, Eldar Giladi, Hua Chang, Alex Kaprelyants, Aeron Hurley, Christina Ernst, Louis Coupal, Teresa Capela, Sibgat Choudhury, Clayton Small, Thomas P. Nifong, Mathew Putzi, Michail Shipitsin, David L. Rimm, David M. Berman, Peter Blume-Jensen
Supplementary Methods, Table S1, Figures S1-7. Methods for quantitative multiplex proteomics imaging (QMPI) Clinical studies: Statistical plan Table S1. Clinical Validation Study. Comparison of Predictive Value of the 8-Biomarker Assay for Favorable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a775876007c847964815ceef0082305
https://doi.org/10.1158/1078-0432.22459749
https://doi.org/10.1158/1078-0432.22459749
Autor:
Sibgat Choudhury, J. Dunyak, David M. Berman, Aeron D. Hurley, Eric A. Klein, Julie Nardone, Louis Coupal, Thomas P. Nifong, Fred Saad, Peter Blume-Jensen, David L. Rimm, Teresa Capela, Massimo Loda, Philip W. Kantoff, Hua Chang, Mathieu Latour, Christina Ernst, Cristina Magi-Galluzzi, Mathew Putzi, Clayton Small, Alex Kaprelyants, Michail Shipitsin, Jonathan I. Epstein, Eldar Giladi
Publikováno v:
Clinical Cancer Research. 21:2591-2600
Purpose: Prostate cancer aggressiveness and appropriate therapy are routinely determined following biopsy sampling. Current clinical and pathologic parameters are insufficient for accurate risk prediction leading primarily to overtreatment and also m
Autor:
Julie Nardone, Peter Blume-Jensen, Massimo Loda, Christina Ernst, Shaun A. Hussain, Thomas P. Nifong, David L. Rimm, S Friedlander, Sibgat Choudhury, Y E Huang, Michail Shipitsin, Catherine B. Small, David M. Berman, H. Chang, Aeron D. Hurley, J. Dunyak, Eldar Giladi
Publikováno v:
British Journal of Cancer
Background: Key challenges of biopsy-based determination of prostate cancer aggressiveness include tumour heterogeneity, biopsy-sampling error, and variations in biopsy interpretation. The resulting uncertainty in risk assessment leads to significant
Autor:
Ludovica Riera, Michael J. Comb, Claudia Voena, Giorgio Inghirami, Francesco Boccalatte, Amalia Bosia, Ole N. Jensen, Roberto D. Polakiewicz, John Rush, Julie Nardone, Valerie Goss, Bruce Ruggeri, Mangeng Cheng, Kimberly Lee, Roberto Chiarle, Chiara Riganti, Lucia D'Amico
Publikováno v:
Boccalatte, F E, Voena, C, Riganti, C, Bosia, A, D'Amico, L, Riera, L, Cheng, M, Ruggeri, B, Jensen, O N, Goss, V L, Lee, K, Nardone, J, Rush, J, Polakiewicz, R D, Comb, M J, Chiarle, R & Inghirami, G 2009, ' The enzymatic activity of 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (ATIC) is enhanced by NPM-ALK : new insights in ALK-mediated pathogenesis and the treatment of ALCL ', Blood, vol. 8, no. 3, pp. 2776-2790 . https://doi.org/10.1182/blood-2008-06-161018
Anaplastic large cell lymphoma represents a subset of neoplasms caused by translocations that juxtapose the anaplastic lymphoma kinase (ALK) to dimerization partners. The constitutive activation of ALK fusion proteins leads to cellular transformation
Autor:
Matthew P. Stokes, Anthony Possemato, Randall K. Wetzel, Jeffrey Mitchell, Michael J. Comb, Julie Nardone, Kimberly Lee, Judit Villén, Joan MacNeill, Roberto D. Polakiewicz, Jon M. Kornhauser, Gregory Innocenti, John Rush, Ailan Guo, Klarisa Rikova, Yi Wang, Steven P. Gygi
Publikováno v:
Proceedings of the National Academy of Sciences. 105:692-697
A major question regarding the sensitivity of solid tumors to targeted kinase inhibitors is why some tumors respond and others do not. The observation that many tumors express EGF receptor (EGFR), yet only a small subset with EGFR-activating mutation
Autor:
Roberto D. Polakiewicz, Cynthia Reeves, John Rush, Lana Popova, Stephen D. Nimer, Ting-Lei Gu, Julie Nardone, Joan MacNeill
Publikováno v:
Leukemia. 21:563-566
Phosphoproteomic analysis identifies the M0-91 cell line as a cellular model for the study of TEL-TRKC fusion-associated leukemia