Human Endogenous Retrovirus K Envelope in Spinal Fluid of Amyotrophic Lateral Sclerosis Is Toxic

Autor: Joseph P. Steiner, Muzna Bachani, Nasir Malik, Catherine DeMarino, Wenxue Li, Kevon Sampson, Myoung‐Hwa Lee, Jeffery Kowalak, Manju Bhaskar, Tara Doucet‐O'Hare, Marta Garcia‐Montojo, Maria Cowen, Bryan Smith, Lauren Bowen Reoma, Julie Medina, Joanna Brunel, Justine Pierquin, Benjamin Charvet, Hervé Perron, Avindra Nath

Publikováno v: Annals of neurology. 92(4)

Human endogenous retroviruses have been implicated in neurodegenerative diseases including amyotrophic lateral sclerosis (ALS). Expression of human endogenous retrovirus K (HERV-K) subtype HML-2 envelope (Env) in human neuronal cultures and in transg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec13f6ed1cd83ad1d2db93cf4185d74c
https://pubmed.ncbi.nlm.nih.gov/35801347

Hand Deformities in Hajdu-Cheney Syndrome: A Case Series of 3 Patients Across 3 Consecutive Generations

Autor: Julie Medina-Gontier, Jonathan Caballero, I. Jiménez, Jose Medina

Publikováno v: The Journal of Hand Surgery. 46:73.e1-73.e5

Hajdu-Cheney syndrome is a rare condition characterized by acro-osteolysis, osteoporosis, and multiple craniofacial anomalies. The goal of treatment is to reduce the associated symptoms and to prevent osteoporotic fractures. This is a report of 3 pat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::11a7e940731782eb1858e1db8c73094e
https://doi.org/10.1016/j.jhsa.2020.02.012

Optimization of influenza A vaccine virus by reverse genetic using chimeric HA and NA genes with an extended PR8 backbone

Autor: Houda Boukhebza, Amélie De Saint Jean, Régis Sodoyer, Julie Medina, Isabelle Legastelois, Catherine Moste

Publikováno v: Vaccine. 33:4221-4227

The yield of influenza antigen production may significantly vary between vaccine strains; for example the A/California/07/09 (H1N1)-X179A vaccine virus, prepared during 2009 influenza pandemic, presented a low antigen yield in eggs compared to other

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d4ddb4acbe2a4c47e9663d822aaf336
https://doi.org/10.1016/j.vaccine.2015.06.112

Des séquences rétrovirales endogènes dans le génome humain peuvent jouer un rôle physiologique ou pathologique

Autor: Pascal Leblanc, Hervé Perron, Julie Medina, Patrice N. Marche, Branka Horvat, Benjamin Charvet, Raphaële Germi

Publikováno v: médecine/sciences
médecine/sciences, EDP Sciences, 2017, 33 (4), pp.397-403. ⟨10.1051/medsci/20173304009⟩
médecine/sciences, 2017, 33 (4), pp.397-403. ⟨10.1051/medsci/20173304009⟩

Human endogenous retroviruses (HERV) represent a large part of our genome and the few elements that have retained a potential of expression still remain "dormant" in physiological conditions. In some instances, they can be awakened by environmental f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b70dcdedd4ef8b1f47681c980269cce
https://www.hal.inserm.fr/inserm-02333322/document

Vero/CHOK1, a novel mixture of cell lines that is optimal for the rescue of influenza A vaccine seeds

Autor: Emmanuelle Totain, Julie Medina, Catherine Moste, Vincent Guillot, Isabelle Legastelois, Régis Sodoyer, Marie Rouleau

Publikováno v: Journal of Virological Methods. 196:25-31

Seasonal and pandemic influenza vaccine manufacturing is challenged with a tight production schedule. Reverse genetics constitutes a rapid method for creating viruses. Vero and CHOK1 cells were found to be an appropriate cell mixture for the generati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5291761c8a34addcb80adb537801d6d
https://doi.org/10.1016/j.jviromet.2013.09.007