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pro vyhledávání: '"Julie McMullen"'
Autor:
Nicola M. Sergienko, Helen Kiriazis, Daniel Donner, Aya Matsumoto, Jieting Luo, Jeffrey Molendijk, Ben L. Parker, Julie McMullen, Kate Weeks
Publikováno v:
Journal of Molecular and Cellular Cardiology. 173:104-105
Publikováno v:
Circulation Research. 117
The immediate downstream effector of Galpahq is the early signaling enzyme phospholipase Cbeta1b (PLCbeta1b), which is selectively elevated in failing human myocardium. When delivered to the adult mouse heart, expression of PLCbeta1b causes rapid con